Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Pancreatic14 gene list
Transcript
Hereditary Cancer Testing GENE LIST Panel: Pancreatic14 APC BRCA1 CDKN2A MLH1 MSH6 PMS2 TP53 ATM BRCA2 EPCAM MSH2 PALB2 STK11 VHL Approximately 5-10% of pancreatic cancer is hereditary.1 The average person’s risk to develop pancreatic cancer is about 1%, but there are multiple genes that are known to increase a person’s lifetime risk of pancreatic cancer.2 Pancreatic14 is a genetic test that looks for changes in 14 genes associated with a hereditary risk of pancreatic cancer.3-13 GENE APC SYNDROME Familial adenomatous polyposis (FAP) syndrome and attenuated FAP ASSOCIATED CANCERS AND FINDINGS colon, polyps of the colon and GI tract, brain tumors breast, pancreas ATM BRCA1 BRCA2 CDKN2A Hereditary breast and ovarian syndrome breast, ovarian, pancreas, male breast, prostate Cutaneous malignant melanoma syndrome pancreas, skin (melanoma) MLH1 MSH2 MSH6 PMS2 EPCAM PALB2 Lynch syndrome colon, uterine, ovary, stomach, pancreas, and others STK11 Peutz-Jeghers syndrome TP53 Li-Fraumeni syndrome VHL von Hippel-Lindau syndrome breast, pancreas breast, colon, small bowel, stomach, pancreas, ovarian, polyps, and characteristic skin findings breast, sarcoma, brain, adrenocortical, and others kidney, hemangioblastomas of (multiple organs), pheochromocytoma, central nervous system tumors References available on the Human Genetics Laboratory website: www.unmc.edu/mmi/geneticslab/resources/reference-articles.html UNMC Human Genetics Laboratory where excellence is dominant | 402-559-5070 | www.unmc.edu/geneticslab
