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AUTOIMMUNE DISORDERS ARTHRITIS OVERVIEW One of the most common, disabling diseases Three types: Osteoarthritis Gout Rheumatoid Arthritis OSTEOARTHRITIS Wear and Tear on joints Affects mostly older adults; men & women Joint pain, stiffness Relieved by pain relievers and lowimpact exercise GOUT Build up of uric acid in joints Affects mostly older males May be very painful RHEUMATOID ARTHRITIS Autoimmune disorder Causes inflamed tissue that destroys cartilage Affects young and middle-age adults; more females than males May be very painful ANKYLOSING SPONDYLITIS Another type of arthritis Affects the joints of the spine Likely genetic Symptoms / treatment FIBROMYALGIA “Waste basket diagnosis” Complex, chronic pain disorder Affects about 10 million Americans Mostly women FIBROMYALGIA CONTINUED Diagnosis include Detailed history Pain in at least 11 of 18 designated tender points. Other diseases need to be ruled out first Symptoms include: Widespread pain, fatigue, sleep disorders, fibro “fog”, headaches, anxiety, and/or depression CHRONIC FATIGUE SYNDROME (CFS) Another “Waste basket diagnosis” Diagnosis must meet 2 criteria: Patient must have unexplained, persistent fatigue for 6 months or more (other diseases ruled out) Four or more “approved” symptoms must be present for at least 6 months CFS “fog”, unrefreshing sleep, muscle pain, joint pain without swelling, headaches, flu-like symptoms, tender lymph nodes, recurring sore throat CFS CONTINUED May be very debilitating No medications; no cure Complementary & alternative medicines may help Cognitive Behavior Therapy (CBT) Graded Exercise Therapy (GET) SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) Immune system produces antibodies to body cells causing inflammation and tissue damage. One main characteristic: butterfly facial rash Other symptoms: Fatigue, joint pain, fever SLE CONTINUED Affects mostly young women May co-exist with other autoimmune conditions May affect any organ in the body Death usually occurs from organ failure Survival increasing