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Preoperative Cardiac Evaluation Prepared for KMRH residents in Anaesthesia July 2013 Kabul Preoperative Cardiac Evaluation I. II. III. IV. Risk assessment – Patient and Surgical Factors Pre-operative Interventions to modify risk Intra-operative Interventions to modify risk Post Operatively Surveillance Preoperative Cardiac Evaluation Risk assessment : Patient Factors I. Congestive Heart Failure II. MI within 30 days III. Severe Cardiac Arrhythmia including heart block IV. Severe Valvular disease V. Severe or Unstable angina • Other - Remote MI, Diabetes, Renal dysfunction, Poorly managed hypertension, Rhythm other than sinus, Previous or compensated CHF, stable angina treated hypertension, LVH or LBBB, advanced age Preoperative Cardiac Evaluation Patient Factors Congestive Heart Failure MI within 30 days Severe Cardiac Arrhythmia including heart block Severe Valvular disease Severe or Unstable angina These are severe clinical indicators and patients should be evaluated and optimized preoperatively Preoperative Cardiac Evaluation Patient Factors Other - Remote MI, Diabetes, Renal dysfunction, Poorly managed hypertension, Rhythm other than sinus, Previous or compensated CHF, stable angina These are intermediate clinical indicators that may or may not need further evaluation depending on their functional capacity and nature of surgery. Preoperative Cardiac Evaluation Patient Factors • Functional capacity – is the patient able to : Class I – Angina only during strenuous or prolonged physical activity 8-10 METS Class II – Slight limitation, with angina only during vigorous physical activity 6-8 METS Class III –Symptoms with everyday living activities, i.e., moderate limitation 4-6 METS Class IV – Inability to perform any activity without angina or angina at rest, i.e.,severe limitation < 4 METS Cardiac Risks of Noncardiac Surgery Surgical Factors Cardiac stress is inherent to surgery Anaesthetic technique, drugs, pain, and nature of the Surgery all effect : 1. The stress response and catecholamines – increase HR and BP 2. Fluctuations in HR, BP, intravascular volume, oxygenanation, and oxygen transport These factors will cause imbalance in myocardial O2 supply and demand Cardiac Risks of Non-cardiac Surgery Myocardial Oxygen Supply and Demand increased HR decreased HR increased Systolic BP increased wall tension increases chamber pressure adequate coronary circulation increased Diastoloic BP reduced wall tension decreased chamber pressure inadequate coronaries adequate hemoglobin Supply Supply Surgery-specific risks • High risk (>5% cardiac risk) – Emergency major operations • Especially in the elderly – Aortic or major vascular surgery – Extensive operations with large volume shifts or blood loss. Surgery-specific risks • Intermediate risk (<5% cardiac risk) – Intraperitoneal and intrathoracic – Carotid endarterectomy – Head and neck – Orthopedic – Prostate Surgery-specific risks • Low risk surgeries (<1% cardiac risk) – Endoscopic procedures – Superficial biopsies – Cataracts – Breast surgery Assessing the situation • Determine the urgency for surgery – Emergency Surgery – few options – do the best you can • Options to consider (as a team) – – – – – – Postpone or cancel Modify the surgical procedure Delay case (for further testing or patient optimization) Perioperative medical therapy Perioperative monitoring Modification of the location of care Pre-operative Interventions to Modify Risk Investigations • EKG – suitable for most patients over 40 with risk factors • CXR - if any concern from history or physical examination • Bloodwork – if significant co-morbidities or chance of significant blood loss • Consultation – changing nature of symptoms ( eg worsening angina ) or concern regarding valvular integrity or ventricular function – Testing may include echocardiography or cardiac stress testing – Medications may be adviseable – B blockers, statins, ASA, others – Invasive intervention should be based on symptoms, not surgery Intra-operative Interventions to Modify Risk • Consider : – – – – – Anaesthetic Technique Intra operative Monitoring Choice of Drugs Post operative analgesia Post operative care Intra-operative Interventions to Modify Risk: Anaesthetic Technique • Regional Anaesthesia – – Minimizes the hormonal stress response – Spinal/Epidural techniques require consideration of hemodynamic changes – Never been shown superior or safer to GA – Some benefit to graft patency for peripheral vascular surgery Intra-operative Interventions to Modify Risk: Choice of Drugs Optimization of myocardial O2 supply/demand is the goal !!! • B blockers pre or intra operatively may reduce incidence of adverse cardiac events , may increase risk of cerebrovascular events • All volatiles (except N2O) are vasodilators and reduce contractility – so they may reduce demand, but also reduce supply ! Some ( sevoflurane ) may have intrinsic cardio-protective effects • Vasopressors alpha agents ( neosynephrine ) may help increase coronary perfusion pressure and may be useful in conjunction with B blockers Intra-operative Interventions to Modify Risk Choice of Drugs • Ketamine increases HR and contractility but may minimize post induction hypotension – consider combining it with midazolam to reduce unwanted effects • NTG enhances coronary perfusion but reduces BP and filling pressure • ACE inhibitors and Angiotensin receptor blockers Beware as they may cause profound post induction hypotension unresponsive to sympathomimetics – may require small dose vasopressin (0.4 U) • Post op Analgesia will reduce the stress response if adequate. Consider multimodal approach including neuraxial opioids ( if appropriate monitoring available ) Intra-operative Interventions to Modify Risk: Monitoring • Invasive monitoring may assist in guiding fluid management, provide early warning to hemodynamic changes, and allow blood analysis • EKG additional leads ( 5 lead ) may allow detection of up to 70 % of ischemic events Post Operative Surveillance • Post operative cardiac events – peak at 48 hrs post op – Myocardial infarctions are often silent with 50% mortality – CHF as a result of remobilization of intra-operative fluids – Consider intermediate care area for high risk patients Preoperative Evaluation Algorithm Putting it all together Preoperative Evaluation Algorithm Putting it all together • For patients with major clinical predictors undergoing non-emergent noncardiac surgery, consider delaying the surgery. – Medical management – Medical Risk factor modification – Consider invasive/non-invasive testing Preoperative Evaluation Algorithm Putting it all together • For patients with intermediate clinical predictors, • • evaluate functional status. Moderate to good functional status (>4 mets) promps us to look at the procedure itself. Low functional status (<4 METs) may merit further testing. Preoperative Evaluation Algorithm Putting it all together • For patients without intermediate clinical predictors, moderate to good functional status indicates lowest cardiac risk for all procedures • Poor functional status should always prompt us to evaluate the surgical procedure and consider further testing Preoperative evaluation algorithm • Consider noninvasive testing if two or more are present: – Intermediate clinical predictors – Poor functional capacity – High surgical risk procedure Therapeutic Preoperative Interventions at KMRH • Invasive options available ? ( PCTA, stents, CABG ) for • • severe symptoms Medical optimization Stress testing, Echocardiography may direct you to modify your anaesthetic plans Thank You