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Pediatric Board Review Mark Heller, MD Department of Emergency Medicine Mount Sinai School of Medicine Question 1 An 8 year old male is brought into the ED by his mother. Mom she has noticed that over the last month her son has been limping. When asked why he is limping, the boy states that he has a dull pain in his groin, L thigh, and L knee, that gets worse when he is outside playing. On physical exam there is limited abduction of hip & limited internal rotation in both flexion & extension. The following X-ray is obtained: Question 1 What is the most likely diagnosis? a) Toxic Tenosynovitis b) Turberculous arthritis c) Slipped Capital Femoral Epiphysis d) Legg-Calve-Perthes e) Tumor Q 1 Answer What is the most likely diagnosis? a) Toxic Tenosynovitis b) Turberculous arthritis c) Slipped Capital Femoral Epiphysis d) Legg-Calve-Perthes e) Tumor MLH Q1 Legg-Calve-Perthes’ Disease • Avascular necrosis of the proximal femoral head • Femoral head collapses with potential for subluxation • Onset between 4 to 9 • 5 to 1 male to female ratio • Presents with: – Limp – Chronic dull pain in groin, thigh, knee – Pain worsens with activity Legg-Calve-Perthes’ Disease • 4 Stages – – – – Widening of the cartilage space Subchondral stress fracture of the femoral head Increased femoral head opacification Deformity of the femoral head • Bone Scan and MRI are the best imaging studies • Ortho consult and admission for traction and surgery Question 2 Which of the following findings most strongly suggests that a patient has chickenpox and not smallpox? a) b) c) d) e) Absence of pustules the proximal arms Both crusts and papules are present on the right hand Characteristic lesions are noted in the oropharynx Greatest density of lesions is on the face and neck Patient has fever, myalgias, malaise, and headache Q 2 Answer Which of the following findings most strongly suggests that a patient has chickenpox and not smallpox? a) b) c) d) e) Absence of pustules the proximal arms Both crusts and papules are present on the right hand Characteristic lesions are noted in the oropharynx Greatest density of lesions is on the face and neck Patient has fever, myalgias, malaise, and headache PEER VII Q56 Chickenpox • Incidence of varicella declining secondary to Immunizations • More common in children <10 years old • Highly contagious from prodrome until all lesions are crusted over • Rash starts as red macules on scalp or trunk and within a day vesiculate • Rash spreads outward – Sparing palms and soles Chickenpox Chickenpox (continued) • Multiple states of rash on same body part • Low-grade fever, malaise, and headache • Treatment is symptomatic – Varicella-zoster immune globulin and acyclovir for immunocompromised children Smallpox • Natural cases eradicated • Virus only exist in two known laboratories in the world • Possible biological weapon • Rash involves Palms and Soles • Lesions appear in same stage • Vaccine given within 3 days of exposure is protective • Exposed person quarantined for 18 days • 30% mortality for unvaccinated persons Smallpox vs. Chickenpox Question 3 A 17 year old boy with Type I diabetes mellitus presents with diabetic ketoacidosis. A venous blood gas analysis is conducted, and the pH is 7.09. Treating this patient with bicarbonate could result in which of the following complications: a) b) c) d) e) CSF alkalosis Hypokalemia Hypotonicity Increased work of breathing Rightward shift of the oxyhemoglobin dissociation curve Q 3 Answer A 17 year old boy with Type I diabetes mellitus presents with diabetic ketoacidosis. A venous blood gas analysis is conducted, and the pH is 7.09. Treating this patient with bicarbonate could result in which of the following complications: a) b) c) d) e) CSF alkalosis Hypokalemia Hypotonicity Increased work of breathing Rightward shift of the oxyhemoglobin dissociation curve PEER VII Q57 Pediatric Diabetic Ketoacidosis • 27-40% of new-onset diabetics present in DKA • DKA Definition – Metabolic acidosis (pH < 7.25 or serum bicarb < 15 mEq/L) – hyperglycemia (glucose > 300 mg/dL) – Ketonemia • DKA Presentation – – – – – – Hyperventilation Fruity breath odor Abdominal Pain Lethargy Kussmaul’s respirations (Deep and Labored Breathing) Decreased level of consciousness or coma DKA (continued) • Treatment – Volume Replacement • Calculate Total Fluid Deficit • Normal Saline at 10 to 20 mL/kg over 1 to 2 hours • After initial bolus replace remaining fluid deficit over 24 to 48 hours using 0.45% NS. • At glucose 300 – 250 mg/dL switch to 5% dextrose in 0.45% NS – Insulin Therapy • Regular Insulin infusion of 0.1 U/kg/hr • Increase to 0.2 U/kg/hr if no improvement after 2 hours • No need for bolus DKA (continued) • Treatment – Correction of Electrolyte Abnormalities • Potassium is critical • Add 30 to 40 mEq K to each litter of maintenance fluids • Bicarbonate Therapy – Not recommended – May lead to • • • • Hypokalemia Cerebral Edema Hypernatremia Worsening tissue hypoxia Question 4 A 20 year old woman presents with a painful right ear. She has no history of ear problems but swims several times a week. Examination reveals erythema of the external auditory canal with some purulent discharge and a perforation in the tympanic membrane. The treatment option most likely to damage her ear is: a) b) c) d) e) Ciprofloxacin otic and hydrocortisone otic suspension Hydrocortisone and acetic acid otic solution Neomycin/polymyxn/hydrocortisone otic suspension Ofloxacin otic solution Penicillinase-resistant penicillin Q 4 Answer A 16 year old female presents with a painful right ear. She has no history of ear problems but swims several times a week. Examination reveals erythema of the external auditory canal with some purulent discharge and a perforation in the tympanic membrane. The treatment option most likely to damage her ear is: a) b) c) d) e) Ciprofloxacin otic and hydrocortisone otic suspension Hydrocortisone and acetic acid otic solution Neomycin/polymyxn/hydrocortisone otic suspension Ofloxacin otic solution Penicillinase-resistant penicillin PEER VII Q59 Otitis Externa • Inflammatory process involving the auricle, external auditory canal, and surface of the TM • Caused by gram-negative eneric organisms, Staph aureus, Pseudonomas, or fungi • Peak age 9 to 19 years • Erythema, edema of EAC, white exudate on EAC and Tm • Pain with motion of tragus or auricle Otitis Externa (continued) • Treatment – Fluoroquinolone otic drops – Oral antibiotics if auricular cellulitis is present or TM is perforated (Quinolones, Cephalosporins, or penicillinase-resistant pcn) • Hydrocortisone and acetic acid otic solution have a pH 3.0 which can be toxic to the middle ear in perforations Otitis Externa Otitis Media • • • • • Infection of the middle ear Infants and Young Children (peaks at 6 to 18 months) 25 to 30 million office visits per year Strep pneumoniae most prevalent cause Symptoms include fever, poor feeding, irritability, vomiting, earache, otorrhea • Signs include dull, bulging, immobile TM – Light reflex is of no diagnostic value • Treatment – Amoxicillin 80 mg/kg/day PO divided q8 – q12 for 10 days (Highdose amox therapy) Otitis Media Otitis Media Name That Celebrity Name That Celebrity Britney Spears Name That Celebrity Name That Celebrity Drew Barrymore Name That Celebrity Name That Celebrity Eminem Question 5 A 2 year old girl is brought in by her parents for persistent fever for the past 5 days. On examination, she has bright red injected lips, pharyngeal erythema, cervical lymphadenopathy, conjunctivitis, and a scarlatiniform rash. Which of the following is an essential element in the therapy of this child’s disease? a) b) c) d) e) Amoxicillin-clavulanate Benzathine Penicillin Droplet isolation precautions Intravenous immune globulin Plasma Exchange Q 5 Answer A 2 year old girl is brought in by her parents for persistent fever for the past 5 days. On examination, she has bright red injected lips, pharyngeal erythema, cervical lymphadenopathy, conjunctivitis, and a scarlatiniform rash. Which of the following is an essential element in the therapy of this child’s disease? a) b) c) d) e) Amoxicillin-clavulanate Benzathine Penicillin Droplet isolation precautions Intravenous immune globulin Plasma Exchange PEER VII Q61 Kawasaki Disease • Clinical Findings – Fever for at least 5 days – Bilateral conjunctivitis – Changes of the oral mucosa (erythematous lips, strawberry tongue, erythematous oropharynx) – Changes of the hands and feet (erythema, edema, desquamation) – Rash (scarlatiniform or morbilliform exanthem on trunk) – Cervical Lymphadenopathy • Peak incidence at 1 to 2 years • Season distribution – winter/spring • No clear agent identified Kawasaki Disease • Immune response during KD leads to systemic vasculitis • Treatment – Single infusion of Intravenous Immune Globulin (2 g/kg IV over 8 to 12 hours) – Aspirin 80 to 100 mg/kg/day in four divided doses – ASA continued until afebrile, then reduced to 3 to 5 mg/kg daily for 6 to 8 weeks • Untreated KD will cause coronary artery aneurysm in 20 – 25% of patients • Risk of aneurysm reduced to 3 – 4% with treatment Question 6 A 4 year old boy presents after sticking a fork into a home electrical outlet with his right hand and getting shocked. His right elbow was on the ground at the time. Although he cried initially, he has remained asymptomatic. Physical examination reveals two extremely small first-degree burns on his right hand and elbow, a 12-lead EKG is normal. The most appropriate disposition is: a) Admit to a monitored bed for 24 hours b) Admit to a non-monitored bed for serial peripheral vascular examinations c) Discharge home d) Observe in the emergency department for 6 hours, if no dysrhythmias occur, discharge home. e) Perform echocardiography in the emergency department Q 6 Answer A 4 year old boy presents after sticking a fork into a home electrical outlet with his right hand and getting shocked. His right elbow was on the ground at the time. Although he cried initially, he has remained asymptomatic. Physical examination reveals two extremely small first-degree burns on his right hand and elbow, a 12-lead EKG is normal. The most appropriate disposition is: a) Admit to a monitored bed for 24 hours b) Admit to a non-monitored bed for serial peripheral vascular examinations c) Discharge home d) Observe in the emergency department for 6 hours, if no dysrhythmias occur, discharge home. e) Perform echocardiography in the emergency department PEER VII Q96 Electric Shock • Three populations – Toddlers – household electrical sockets and cords – Teenagers – power lines – Adults – work with electricity • • • • Voltage gives idea of potential damage Admit any electrical injury over 600 V Household V ranges 110 to 220 V Asymptomatic on presentation and have normal EKG can be discharged home Question 7 For young children with sickle cell disease, which of the following tests is most useful in differentiating a splenic sequestration crisis from an aplastic crisis? a) b) c) d) e) Erythrocyte Sedimentation Rate Hemoglobin Level Peripheral WBC Count Platelet Count Reticulocyte Count Q 7 Answer For young children with sickle cell disease, which of the following tests is most useful in differentiating a splenic sequestration crisis from an aplastic crisis? a) b) c) d) e) Erythrocyte Sedimentation Rate Hemoglobin Level Peripheral WBC Count Platelet Count Reticulocyte Count PEER VII Q146 Sickle Cell Disease • Sickle Cell Emergencies – Vaso-oclusive Crisis – Hematologic Crisis – Infections • All SCD children with fever, pain, respiratory distress or change in neurological function require a thorough ED evaluation • 8% of AA population are carriers • 0.15% (1/500) are homozygous • 20-30% of all deaths from SCD occur before 5 Sickle Cell Disease Sickle Cell Disease (continued) • Vaso-Oclusive Crisis – Intravascular sickling – Tissue ischemia and infarction – ED Management • Aggressive hydration • Analgesics – Acute Chest Syndrome • • • • Pneumonia, Pulmonary Infarction, Pulmonary Emboli CXR, CBC, Retic Count, Blood Cultures IV hydration, Analgesic, Abx, Transfusion All warrant hospital admission Sickle Cell Disease (continued) • Hematological Crisis – Acute Sequestration Crisis • • • • • • • Spleen traps large portion of circulating blood Hypotension, shock and death Often preceded by viral infections (Parvovirus B19) CBC shows profound anemia Reticulocyte Counts are Elevated Transfuse PRBC Admission Sickle Cell Disease (continued) • Hematological Crisis – Aplastic Episode • Precipitated by Viral or Bacterial infections • Present with gradual onset of pallor, dyspnea, fatigue, and jaundice • CBC shows low hematocrit (10% or lower) • Reticulocyte Counts are Decreased • Transfuse PRBC • Admit Sickle Cell Disease (continued) • Infections – SCD children are functionally asplenic – Higher risk for bacterial infections, especially encapsulated organisms – Routine Haemophilus influenzae and pneumococcal vaccinations – Fevers are managed aggressively – Treat with antibiotics covering Strep pneumoniae and H. influenzae (eg, ceftriaxone) – Low threshold for admission Question 8 A 17 year old man presents with left eye irritation. He was walking in a park and accidentally ran into a tree branch. He believes the branch scratched his eye. Examination reveals a corneal abrasion. The best treatment option is: a) Erythromycin ophthalmic ointment, no patch. b) Erythromycin ophthalmic ointment, patch c) Homatropine, no patch d) Homatropine, patch e) Topical anesthetic Q 8 Answer A 17 year old man presents with left eye irritation. He was walking in a park and accidentally ran into a tree branch. He believes the branch scratched his eye. Examination reveals a corneal abrasion. The best treatment option is: a) Erythromycin ophthalmic ointment, no patch b) Erythromycin ophthalmic ointment, patch c) Homatropine, no patch d) Homatropine, patch e) Topical anesthetic PEER VII Q 160 Corneal Abrasions Corneal Abrasions • Very Painful • Fluorescein reveals dye update at abrasion site • Treatment – Topical Erythromycin, Tobramycin, or Bacitracin/Polymyxin – Tetanus updated – Patching does not facilitate abrasion healing – Topical anesthetics strictly contraindicated • Cause corneal breakdown and ulceration – Cycloplegic agents (homatropine) not recommended • Recent studies show no benefit (Carley and Carley 2001) Name That Celebrity Name That Celebrity Jennifer Lopez Name That Celebrity Name That Celebrity Leonardo DiCaprio Name That Celebrity Name That Celebrity Michael Jordan Question 9 A 13 year old boy presents with right hip discomfort that has been getting worse for the past 2 to 3 weeks. He denies trauma, fever, and recent illness. His mother says that ibuprofen “helps a little.” Physical examination reveals an obese adolescent boy. Active and passive motion of the left hip elicit pain. Radiographs are obtained. Question 9 Question 9 What is the most likely diagnosis? a) Femoral Neck Fracture b) Legg-Calve-Perthes disease c) Septic arthritis d) Slipped capital femoral epiphysis e) Transient synovitis Q 9 Answer A 13 year old boy presents with right hip discomfort that has been getting worse for the past 2 to 3 weeks. He denies trauma, fever, and recent illness. His mother says that ibuprofen “helps a little.” Physical examination reveals an obese adolescent boy. Active and passive motion of the left hip elicit pain. Radiographs are obtained. What is the most likely diagnosis? a) Femoral Neck Fracture b) Legg-Calve-Perthes disease c) Septic arthritis d) Slipped capital femoral epiphysis e) Transient synovitis Slipped Capital Femoral Epiphysis • • • • SCFE more common in boys Peak from 10 to 15 years old Present with pain in groin, thigh, or knee Hip should not be forced through full range of motions – may displace epiphysis further • X-rays – AP view shows medial slips – Frog-leg view shows posterior slips • Management is operative Slipped Capital Femoral Epiphysis Question 10 A 13 year old boy is brought in by his parents for sudden onset of groin pain. On examination, the patient’s right testis is swollen, tender, and slightly elevated in the scrotum. Which of the following statements regarding this condition is correct? a) b) c) d) CT of the affected area is the imaging study of choice Duplex utrasonography provides little data about testicular anatomy Positive cremasteric reflex confirms the diagnosis Relief of pain with elevation reliably differentiates this condition from epididymitis e) The “bell-clapper” deformity predisposes patients to this condition Question 10 A 13 year old boy is brought in by his parents for sudden onset of groin pain. On examination, the patient’s right testis is swollen, tender, and slightly elevated in the scrotum. Which of the following statements regarding this condition is correct? a) b) c) d) CT of the affected area is the imaging study of choice Duplex utrasonography provides little data about testicular anatomy Positive cremasteric reflex confirms the diagnosis Relief of pain with elevation reliably differentiates this condition from epididymitis e) The “bell-clapper” deformity predisposes patients to this condition PEER VII Q175 Testicular Torsion Testicular Torsion • Time is Testis • Peak incidence at 13 • Pt presents with sudden and severe pain: – Lower Abdomen – Inguinal canal – Testis • Affected testis is elevated • Cremasteric reflex is absent • No relief of pain with elevation of testis (think epididymitis) • 96% salvage rate if detorsed in less than 4 hours • 10% salvage rate if longer than 24 hours Testicular Torsion (continued) • Bell-Clapper Deformity – Testis not fixed in place to posterior scrotum – Freely mobile – Predisposes pt to testicular torsion Testicular Torsion (continued) • Treatment – Detorsion in ED – Lateral-to-medial rotation of affected testis – “Opening a Book” • Urologic referral mandated • Color Doppler to access blood flow • Possible surgical exploration Question 11 In the treatment of a 3 year old boy with a urinary tract infection, which of the following additional signs is the strongest indication for hospital admission? a) b) c) d) e) Localized myalgias Maculopapular rash Marked fever Mucoid diarrhea Persistent vomiting Q 11 Answer In the treatment of a 3 year old boy with a urinary tract infection, which of the following additional signs is the strongest indication for hospital admission? a) b) c) d) e) Localized myalgias Maculopapular rash Marked fever Mucoid diarrhea Persistent vomiting PEER VII Q215 Pediatric UTI • Clinic features vary by age • Neonates – Septic-like appearance – Fever, Jaundice, Poor Feeding, Irritability , and Lethargy • Infants – Gastrointestinal complaints – Fever, Abdominal pain, Vomiting • Older Children – Urinary frequency, urgency, hesitancy, dysuria – Fever, chills, back pain, vomiting, dehydration Pediatric UTI (continued) • Urine Culture is Gold Standard • E. Coli accounts for vast majority • Urine dip – Leukocyte Esterase – Urinary Nitrites Pediatric UTI (continued) • Treatment Depend on Age • Infants < 3 months – Hospitalized – Intravenous antibiotics (ampicillin, cefotaxime, Ceftriaxone) • Older Infants and Children – Single dose of ceftriaxone in ED and out patient oral antibiotics (cephalexin, amoxicillin-clavulanate) • Older infants and children with fever and UTI complicated by vomiting, dehydration, sepsis, inability to take oral antibiotics need to be hospitalized for IV abx. Question 12 A 2 year old boy is brought to the emergency department by his parents immediately after he was discovered “eating a few of his grandmother’s pills.” The grandmother, who is visiting from out of town, keeps her pills in an unlabeled, multi-compartment plastic container that organizes her medications by the day of the week. The parents think the boy ingested 1 day’s worth of pills. He is asymptomatic. Which of the following is the best next step? a) Administer activated charcoal along with a flavoring agent b) Feed the child syrup of ipecac to induce emesis c) Have the child ingest sorbitol to induce osmotic catharsis d) Initiate whole-bowel irrigation with polyethylene-glycol e) Perform gastric lavage with room temperature isotonic saline Q 12 Answer A 2 year old boy is brought to the emergency department by his parents immediately after he was discovered “eating a few of his grandmother’s pills.” The grandmother, who is visiting from out of town, keeps her pills in an unlabeled, multi-compartment plastic container that organizes her medications by the day of the week. The parents think the boy ingested 1 day’s worth of pills. He is asymptomatic. Which of the following is the best next step? a) Administer activated charcoal along with a flavoring agent b) Feed the child syrup of ipecac to induce emesis c) Have the child ingest sorbitol to induce osmotic catharsis d) Initiate whole-bowel irrigation with polyethylene-glycol e) Perform gastric lavage with room temperature isotonic saline PEER VII Q236 Unknown Ingestion • Activated Charcoal reduces toxin absorption by as much as 75% when given within 1 hour • Another option is to contact grandmother’s pharmacy to identify medications and develop a management plan. Only effective if done rapidly. Name That Celebrity Name That Celebrity Paul McCartney Name That Celebrity Name That Celebrity Robert De Niro Name That Celebrity Name That Celebrity Tom Cruise Question 13 A 10 month old boy is brought in by his parents after he turned blue at home. The mother says he has been fussy recently, which she presumed to be caused by teething. She has been treating him with an over-the-counter topical teething gel. On examination, the boy has marked cyanosis, including the perioral area and nail beds. Vital signs reveal a mild degree of tachypnea and tachycardia. Room air oxygen saturation is 88% and does not improve on high-flow oxygen. His lungs are clear, work of breathing is normal, as are heart tones. Which of the following treatments is most likely to be successful in treating this child’s cyanosis? a) b) c) d) e) Botulinum antitoxin Deferoxamine Methylene blue Prostaglandin E1 Sodium Bicarbonate Question 13 A 10 month old boy is brought in by his parents after he turned blue at home. The mother says he has been fussy recently, which she presumed to be caused by teething. She has been treating him with an over-the-counter topical teething gel. On examination, the boy has marked cyanosis, including the perioral area and nail beds. Vital signs reveal a mild degree of tachypnea and tachycardia. Room air oxygen saturation is 88% and does not improve on high-flow oxygen. His lungs are clear, work of breathing is normal, as are heart tones. Which of the following treatments is most likely to be successful in treating this child’s cyanosis? a) b) c) d) e) Botulinum antitoxin Deferoxamine Methylene blue Prostaglandin E1 Sodium Bicarbonate PEER VII Q245 Methemoglobinemia • An oxidant stress from either a drug or chemical eliminates methemoglobin, altering the structure of hemoglobin, causing it to no longer carry oxygen • Medications – Phenazopyridine – Benzocaine (ingredient in common teething gels) – Dapsone (HIV abx therapy) • Clinical Features – Pulse Ox 80-85% on and off supplemental oxygen – “Chocolate brown” blood noted on blood draw – Pt appears cyanotic Methemoglobinemia (continued) • Diagnosis – Cyanosis unresponsive to oxygen – ABG will have falsely normal oxygen saturation – Definitive identification relies on Co-Oximetry • Can differentiate oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, methemoglobin • Co-Oximetry can be run on a venous blood sample • Treatment – Methylene Blue – Effects seen within 20 minutes Question 14 A pediatrician calls the emergency department and leaves the following message with a nurse: “Private patient en route to ER from home by car. Mother says child (male) is jerking and feels hot. No meds, no PMHX. Suspect simple febrile seizure.” Assuming that the pediatrician’s suspicion is correct, which of the following most likely describes this patient and his emergency department encounter? a) b) c) d) e) 2 weeks old, afebrile and well appearing on arrival, had a generalized seizure at home that lasted 10 minutes 4 months old, febrile on arrival, had a generalized seizure at home that lasted 10 minutes, urinary tract infection diagnosed by emergency physician 19 months old, febrile and well appearing on arrival, had a generalized seizure at home that lasted 10 minutes 23 months old, well appearing on arrival, had two generalized seizures at home that lasted 5 minutes each 9 years old, febrile and having generalized seizure on arrival, had twitching of one hand at home that lasted 10 minutes. Q 14 Answer A pediatrician calls the emergency department and leaves the following message with a nurse: “Private patient en route to ER from home by car. Mother says child (male) is jerking and feels hot. No meds, no PMHX. Suspect simple febrile seizure.” Assuming that the pediatrician’s suspicion is correct, which of the following most likely describes this patient and his emergency department encounter? a) b) c) d) e) 2 weeks old, afebrile and well appearing on arrival, had a generalized seizure at home that lasted 10 minutes 4 months old, febrile on arrival, had a generalized seizure at home that lasted 10 minutes, urinary tract infection diagnosed by emergency physician 19 months old, febrile and well appearing on arrival, had a generalized seizure at home that lasted 10 minutes 23 months old, well appearing on arrival, had two generalized seizures at home that lasted 5 minutes each 9 years old, febrile and having generalized seizure on arrival, had twitching of one hand at home that lasted 10 minutes. PEER VII Q262 Febrile Seizure • Generalized seizure lasting less than 15 minutes • Children 6 months to 5 years old • Occurs once in a 24-hour period • No evidence of intracranial infection • No evidence of neurological abnormalities • Seizure caused by how fast the fever rises rather than the temperature of the fever Febrile Seizure • No need for LP in children over 12 months • No role for anti-seizure meds • Treat fever with acetaminophen, ibuprofen, and tepid water baths • A simple febrile seizure does not predispose the patient to epilepsy Question 15 Which of the following best describes the cough associated with pertussis in infants? a) b) c) d) e) Paroxysmal, staccato cough associated with posttussive emesis Productive cough associated with fever and respiratory failure Repetitive cough followed by a loud and distinct whooping sound Seal-like barking cough associated with inspiratory stridor at rest Weak cough with pooled secretions and very poor air exchange Q 15 Answer Which of the following best describes the cough associated with pertussis in infants? a) b) c) d) e) Paroxysmal, staccato cough associated with posttussive emesis Productive cough associated with fever and respiratory failure Repetitive cough followed by a loud and distinct whooping sound Seal-like barking cough associated with inspiratory stridor at rest Weak cough with pooled secretions and very poor air exchange PEER VII Q353 Pertussis “Whooping Cough” – – – – – – – – – – Caused by bacterium Bordetella pertussis Infants unable to make whooping noise DTaP vaccines One of the leading causes of vaccine-preventable deaths world-wide (300,000 deaths per year) Staccato cough Posttussive emesis Diagnose with a single high antibody titer Admission for infants Supportive care Antibiotics for adults Cough in Children • Pertussis – – – – – – – – – – Also known as “Whooping Cough” Infants unable to make whooping noise Caused by bacterium Bordetella pertussis DTaP vaccines Staccato cough Posttussive emesis Diagnose with a single high antibody titer Admission for infants Supportive care Antibiotics for adults