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STATISTICS David Pieper, Ph.D. [email protected] Types of Variables Categorical Variables  Organized into category  No necessary order  No quantitative measure  Examples  male, female  race  marital status  treatment A and treatment B Types of Variables Continuous Variables  Have specific order  Examples:  weight  temperature  blood pressure  Age  Test  score May be converted to categorical or ordinal Descriptive Statistics  Measures of central tendency  mean  (average) Measures of variability  range  standard deviation Results of Memory Test Age Gender Age Group Student or Parent Total Score 17 M HS S 52 16 M HS S 49 30 F Adult P 50 16 M HS S 47 43 F Adult P 41 36 M Adult P 51 16 F HS S 43 43 F Adult P 41 36 F Adult P 33 Descriptive Statistics for Memory Test Age Total Score 196 196 Minimum 7 12 Maximum 72 54 24.9 37.4 16 8 Number of Cases Mean SD Research Hypothesis  Null hypothesis: relationship among phenomena does not exist  Example: Age does not have an influence on memory Probability and p Values  p < 0.05 1 in 20 or 5% chance groups are not different when we say groups are significantly different  p < 0.01 1  in 100 or 1% chance of error p < 0.001 1 in 1000 or .1% chance of error Type of Statistical Test to Use   Continuous variable as end point 2 groups: t-test 3 or more groups: ANOVA Relation between 2 categorical variables:  Chi-square  Fisher’s  test Exact test (2 x 2) Relation between 2 continuous variables:  Regression analysis or correlation T-test  When comparing 2 groups and endpoint variable is continuous  Purpose is determine if the difference between the 2 groups is unlikely due to chance T-test  Examples:  Blood pressure before and after exercise program  Would parents do better on a memory test than students Results of Memory Test Age Gender Age Group Student or Parent Total Score 17 M HS S 52 16 M HS S 49 30 F Adult P 50 16 M HS S 47 43 F Adult P 41 36 M Adult P 51 16 F HS S 43 43 F Adult P 41 36 F Adult P 33 T-test results comparing Parents and Students Total Score Number Mean SD Students 117 36.3 7.5 Parents 79 39.1 8.1 p < 0.02 Parents had higher scores than students Analysis of Variance (ANOVA)  When comparing 3 or more groups and end-point is continuous  Example: Compare score on memory test among:  Grade school students  Middle school students  High school students  Parents Total Score Analysis of Variance p < 0.03 High School Students and Adults scored better than Grade School or Middle School Students Chi-square Test  When comparing 2 or more groups and the end point is categorical Chi-square Gender and Parent vs Student Student Parent Total Female 65 48 113 Male 52 31 83 Total 117 79 139 p = 0.5 There was no significant gender difference between students and parents Correlation or Regression  When determining if there is a linear relationship between 2 continuous variables  Ranges from -1 to 1 Pearson’s Correlation Coefficient Diastolic BP (mm) Weight (kg) 90 82 140 114 68 56 110 62 100 83 95 110 Is Diastolic BP related to Weight? r = 0.805 p < 0.01 Correlation of Age and Score on Memory Test r = 0.6 No correlation of age and score on memory test Illustrations: Use Graphs p < 0.01 Figure 1: Patients that failed the exercise test had a higher mortality than patients that passed • Label axes • Include brief description Free Statistics Software Mystat: http://www.systat.com/MystatProducts.aspx List of Free Statistics Software: http://statpages.org/javasta2.html