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The Respiratory System Unit 12 Introduction Of all the substances that cells and therefore the body as a whole must have to survive, oxygen is by far the most crucial. The average person will live 4-6 minutes without it! Introduction The respiratory system ensures that the oxygen is supplied to and carbon dioxide is removed from the body’s cells. Introduction The respiratory system: -filters -warms -humidifies -influence speech/sound -make olfaction possible Respiratory System Organs of the Resp. System -nose -pharynx -larynx -trachea -bronchi -lungs Respiratory System Alveoli – millions of thinwalled air filled sacs that are covered by capillaries, facilitating gas exchange via diffusion Respiratory System Respiratory Mucosa – membrane that lines most of the air distribution tubes in the system – mucus (over 125 ml of respiratory mucus is produced daily) Respiratory System Respiratory Membrane – separates the air in the alveoli from the blood in surrounding capillaries The Nose One of the ways air enters the respiratory tract through the external nares or nostrils. It then flows into the left and right nasal cavities. The partition in the nose is called the nasal septum. Why you don’t run in the house with scissors…or forks. The Nose Nerve endings located in nasal mucosa send messages to the brain. The Nose Paranasal Sinuses: -Frontal -Maxillary -Sphenoidal -Ethmoidal Assist in production of sound and lighten skull Pharynx -The “throat.” -About 5 inches long -Divided into 3 portions Pharynx Pharynx Divided into 3 portions - Nasopharynx: uppermost part behind nasal cavity - Oropharynx: behind the mouth - Laryngopharynx: lowest section above the larynx Oropharynx Nasopharynx Laryngopharynx Larynx -”Voice Box” -located below the pharynx -made of cartilage -”Adams Apple” Larynx Larynx Vocal Cords: two short fibrous cords that stretch across the interior of the larynx. Muscles control pitch. Tense – high pitch Relaxed – low pitch Glottis – space between vocal cords Larynx Epiglottis – partially covers opening of the larynx, serves as trap door, closing larynx during swallowing and preventing food from entering trachea. Epiglottis Trachea -”Windpipe” -4.5 inches -extends from larynx to bronchi -open passageway to lungs Trachea Trachea -Made of 15-20 C-Shaped rings of cartilage placed on top of each other. -Lined with respiratory mucosa and cilia moves this mucus upward toward pharynx Trachea The trachea can sometimes become occluded despite its strong cartilage rings by a tumor, enlarged lymph node or foreign body obstruction. For the foreign body obstruction: Heimlich Maneuver Bronchi, Bronchioles, Alveoli The trachea is divided into the left and right bronchus at it’s inferior end, also known as the primary bronchi. Bronchi, Bronchioles, Alveoli The primary bronchi also branch out into secondary bronchi. These also branch out into smaller tubes known as bronchioles, which then become alveolar ducts, holding the alveoli. Bronchi, Bronchioles, Alveoli Surfactant – substance that covers the surface of the respiratory membrane which prevents the alveoli from collapsing as air moves in and out during respiration. Respiration Definition – the exchange of gasses (oxygen & carbon dioxide) between living organism and its environment. Respiration The lungs provide a place where air and circulating blood can come close enough to each other for gas exchange to occur. Respiration External Respiration – exchange of gases between air and lungs Internal Respiration – exchange of gasses between blood and body cells Mechanics of Breathing Inspiration – inhalation, moving air into the lungs; enlarges the chest cavity Expiration – exhalation, moving air out of the lungs Mechanics of Breathing Diaphragm – dome-shaped muscle separating the abdominal cavity from the thoracic cavity; most important muscle of inspiration Lungs Left Lung – 2 lobes Right Lung – 3 Lobes Exchange of Gases In the lungs – through external respiration – diffusion between blood and alveoli In the tissues – through internal respiration – diffusion between capillaries and body cells Volume of Air Exchange Spirometer – special device used to measure the amount of air exchanged during respiration Volume of Air Exchange Tidal Volume – we take about 500ml (about a pint) of air into our lungs with each normal inspiration. Volume of Air Exchange Vital Capacity – the largest amount of air that we can breath out in one expiration Regulation of Respiration Normal Respiratory Rate 12-24 Breaths/min (at rest) Regulation of Respiration Respiratory Control Centers Located in the pons and the medulla (Brain) Regulation of Respiration Respiratory Control Centers Two most important control centers are in the medulla: Inspiratory Center Expiratory Center Regulation of Respiration Cerebral Cortex Controls voluntary changes in respirations. (holding your breath) Types of Breathing Eupnea –Normal breathing Hyperventilation – rapid, deep respirations Hypoventilation – slow, shallow respirations Apnea – Absence of respirations Types of Breathing Cheyne-Stokes Breathing Alternating apnea and hyperventilation (usually associated with critical condition) Types of Breathing Respiratory Arrest Failure to resume breathing after a period of apnea Disorders of Respiratory Syst. Rhinitis – inflammation of the nasal mucosa and is often caused by nasal infections; irritants; allergies Disorders of Respiratory Syst. Pharyngitis – “sore throat”; inflammation or infection of the pharynx; pain, redness, difficulty swallowing; streptococcal infection Disorders of Respiratory Syst. Laryngitis – inflammation of the mucous lining of the larynx; edema of the vocal cords; hoarseness; loss of voice; overuse of voice, smoking Disorders of Respiratory Syst. Epistaxis – medical term for “nosebleed;” most common cause is trauma, but can also be caused by sustained increased blood pressure; rhinitis; brain injury Disorders of Respiratory Syst. Acute Bronchitis – acute inflammation of the bronchi usually caused by infection, can also be caused by irritant or allergy; nonproductive cough that progresses to deep cough – sputum. Disorders of Respiratory Syst. Pneumonia – acute inflammation of the lungs in which the alveoli and bronchi become plugged with thick fluid (exudate); high fever, chills, headache, cough and chest pain Disorders of Respiratory Syst. Aspiration Pneumonia – Pneumonia as a result aspiration. Disorders of Respiratory Syst. Tuberculosis – highly contagious; caused by the pathogen Mycobacterium Tuberculosis; transmitted through inhalation or swallowing of contaminated droplets. Disorders of Respiratory Syst. Tuberculosis – fatigue, chest pain, pleurisy, weight loss, fever Disorders of Respiratory Syst. Atelectasis – total or partial collapse of the alveoli of the lung. Disorders of Respiratory Syst. COPD – Chronic Obstructive Pulmonary Disease; irreversible obstruction of air flow Disorders of Respiratory Syst. COPD – Chronic Bronchitis; chronic inflammation of bronchi and bronchioles; edema and excessive mucus production; smoking is major cause Disorders of Respiratory Syst. COPD – Emphysema; progression of chronic bronchitis; walls of alveoli rupture and fuse together Disorders of Respiratory Syst. COPD – Asthma; recurring spasms of the smooth muscle in the walls of the bronchial air passages; inflammation excessive mucus; stress, exercise, infection, allergens, irritants. Disorders of Respiratory Syst. Lung Cancer – malignancy of pulmonary tissue; may spread (metastasis); 75% of lung cancer is associated with smoking Increased exposure to “second hand” smoke also increases chances of lung cancer. Disorders of Respiratory Syst. Lung Cancer – treatment; Lobectomy – surgical removal of one lobe of lung Pneumonectomy – surgical removal of entire lung. Respiratory System Pulmonologist Allergist Ear Nose & Throat (ENT) Respiratory Therapist End of Lecture