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Reacts to airborne contaminants Major: ◦ ◦ ◦ ◦ ◦ Particulate matter Carbon monoxide (CO) Sulphur dioxide (SO2) Hydrocarbons smog Other air-borne contaminants: ◦ ◦ ◦ ◦ VOC’s Workplace chemicals Pesticides Pathogens Ionizing radiation ◦ Causes atoms to expel electrons and become ions Fly frequently, work in nuclear energy or with x-rays, lasers http://www.youtube.com/watch?v=i9dW0k4afCI&NR=1&feature=fvwp Healthbeat - Children & Air Pollution Reactions (Symptoms) Diseases Examples of Connants or Factors That May Cause Reactions — smoke and smoking, particulates, smog, CO, SO2, VOCs difficulty breathing, wheezing, asthma, chronic obstructive smoke and smoking, particulates, smog, SO2, VOCs, coughing, shortness of breath, pulmonary disease (chronic pathogens excessive mucus, anxiety, weakness bronchitis and emphysema) inflamed lungs, dry cough pneumonia, pneumonitis eyes, nose, & throat irritation; headache smoke and smoking, particulates, hydrocarbons, pathogens chronic cough, difficulty breathing, bloody mucus, chest pain lung cancer smoke and smoking, ionizing radiation, hydrocarbons, workplace chemicals, arsenic, asbestos Reacts to contaminants in foods and liquids Heat and stress may also affect it Many digestive system diseases cause by pathogens ◦ Example: 2008 Listeriosis outbreak across Canada Unclean meat processing plant equipment Reactions (Symptoms) Diseases Examples of Connants or Factors That May Cause Reactions feeling sick, vomiting nausea alcohol abuse, pathogens, stress, heat intestinal inflammation and pain, cholera, dysentery, giardia pathogens vomiting, cramps, watery diarrhea, bloody stools nausea, fatigue, weight loss, coma, kidney cirrhosis alcohol and drug abuse, workplace chemicals failure fever, rash, nausea, headache, exhaustion, listeriosis Listeria monocytogenes pathogen fever, chills, pain, shock, diarrhea septicemia Escherichia coli pathogen vomiting, diarrhea, difficulty breathing, heavy metal poisoning workplace chemicals, drugs difficulty swallowing (esophagus), cancer of the esophagus and alcohol abuse, smoking, workplace chemicals weakness, weight loss, back pain pancreas shock, collapse, circulatory failure headache, intestinal pain (pancreas), clay-coloured stools (pancreas) Workplace and household solvents can be absorbed and irritate skin ◦ Example: bleach = burns skin can be absorbed into blood stream and carried to rest of body Environmental factors ◦ Hot and cold ◦ UV Rays or ionizing radiation can cause Melanoma (skin cancer) ◦ Poison Ivy = skin rash Reactions (Symptoms) Diseases Examples of Connants or Factors That May Cause Reactions rashes, itching eczema, contact cleaning fluids, workplace chemicals, glues, dermatitis disinfectants, oils, heavy metals, pesticides hair loss alopecia ionizing radiation hives, itching urticaria drugs, stress, heat, cold, dust mites sunburn, tumours skin cancer UV rays, ionizing radiation, workplace chemicals severe adult acne chloracne workplace chemicals, PCBs, herbicides loss of pigment leukoderma workplace chemicals Lymphatic system (immune system): glands, nodes Leucocytes (white blood cell) protect against pathogens (not all) Single cell animals (protozoan's, parasites') often survive ◦ Malaria (protozoan) – infected mosquitoe bites Ionizing radiation and chemicals Lymphatic system filters out bacteria and wastes – through lymph nodes and spleen Lymphocytes (specialized WBC) also do this ~ ionizing radiation and chemicals can damage lymphocytes Reactions (Symptoms) Diseases Examples of Connants or Factors That May Cause Reactions fever, chills, confusion, sweating, malaria Plasmodium genus pathogens leukemia (blood cancer) ionizing radiation, VOCs weight loss, fever, night sweats, lymphoma (lymphatic UV and ionizing radiation, PCBs, pesticides enlarged lymph nodes, anemia, system cancer) extreme thirst fatigue, weight loss, fever, weakness, bone and joint pain, infections Brain, spinal cord, nerves Brain and spinal cord = central nervous system (CNS) Nerves and pathways = peripheral nervous system (PNS) Peripheral nervous system (PNS) sends impulses to CNS indicating feeling ◦ pleasure, touch, pain, hunger, thirst, sound, smell, sight, and other stimuli CNS responds by sending command back to muscles, glands, organs in how to respond ◦ Ie. Touch something hot = tells arm to pull away http://www.youtube.com/watch?v=62dVw7QQVJ8&NR=1 Lead Poisoning in Kids Reactions (Symptoms) Diseases Examples of Connants or Factors That May Cause Reactions irritability, numbness; speech, mercury poisoning fungicides, workplace chemicals, connated vision, hearing, thinking, and (Minamata disease) fish and seafood, antiseptics lead poisoning water from lead pipes, lead in paint, coordination problems; vomiting, abdominal pain, kidney failure, coma irritability, burning mouth, nervous system damage, pain, workplace fumes, leaded gasoline mental disturbances, paralysis, convulsions headache, fever, body aches, meningitis, virus nausea, vomiting, drowsiness, encephalitis confusion, weakness, paralysis, loss of consciousness pain, hearing loss deafness excessive noise System Parts Reaction Cause Affect (Disease) Nervous Brain, spinal cord, nerves (CNS, PNS) Irritability, vision, hearing, coordinatio n loss Mercury Minamata poisoning Disease (contaminated fish, seafood, workplace chemicals) Urinary: rid body of wastes ◦ Kidneys filter blood to remove wastes – excrete urine – bladder – emptied ◦ Both vulnerable to environmental contaminants Bladder infections/kidney infections Reactions (Symptoms) Diseases Examples of Connants or Factors That May Cause Reactions blood in urine, flank pain, kidney, bladder cancer fever, tumour smoke and smoking, hydrocarbons, workplace chemicals damaged sperm and eggs fertility problems PCBs, workplace chemicals sexual abnormalities hormone imbalance PCBs, workplace chemicals, non-stick coatings pain, tumours, discomfort, ovarian, breast cancers workplace chemicals, ionizing radiation, weight loss asbestos, talc difficult urination, blood in prostate, testicular urine, tumours, breast cancers enlargement pesticides, heavy metals, PCBs, bisphenol-A System Parts Reaction Cause Affect (Disease) Urinary Kidneys, Bladder Blood in urine, pain, fever Smoking, workplace chemicals, pathogens Kidney, bladder cancer, infection