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White Blood Cells What do they do? Play a large role in the immune system Fight disease and infection Creating antibodies Phagocytosis Doctors can use the amount of white blood cells to determine if our body is fighting an infection. Make a table Neutrophils Abundance Granules? Role Other Eosinophils Basophils Monocyte Lymphocyte 5 Types 2 main categories: Granulocytes = contain granules Neutrophils, Eosinophils, Basophils Agranulocytes = do not contain granules Monocytes, Lymphocytes Neutrophils Most abundant: 40-75% Kill off bacteria One of the first cells to travel to site of inflammation Main cell in “Pus” Eosinophils 1-6% of cells Kill off multicellular parasites Involved in control of allergies and asthma Presence in lungs, skin, and esophagus is a sign of disease Basophils Least common 0.01-0.3% Contain histamine and heparin (an anticoagulant). Help to bring blood to the site of injury to promote healing. May contribute to the severity of allergic reactions. Monocytes BIG! 2-10% Travel to site of infection where they differentiate into MACROPHAGES Elicit a immune response by presenting antigens Lymphocyte Immune system: T-cells and B-cells More on these later!! Ejection of debris by exocytosis https://www.youtube.com/watch?v=UKwwvIaR9aI https://www.youtube.com/watch?v=r4-g6tVyUAU https://www.youtube.com/watch?v=aWItglvTiLc