Download Basic Facts on HIV/AIDS

Basic Facts on HIV/AIDS
By David Schulman
Learning objectives
By the end of this presentation you will be able
to:
• Discuss the difference between HIV and AIDS.
• Understand how HIV attacks the body’s
health.
• Describe the impact of HIV on the immune
system.
• Understand HIV risk
Understanding HIV and AIDS
HIV
• HIV is short for the HUMAN IMUNNO
DEFICIENCY VIRUS.
• HIV attacks the immune system – the
body’s defence against disease.
• HIV can live in our bodies for years
without obvious effects. HIV does not
usually cause immediate incapacity in
a person.
• Research shows that employees with
asymptomatic HIV (showing no
symptoms) are as productive, and
work as many hours, as other
employees. It is usually only when a
person develops AIDS – related illness,
that a person becomes noticeably and
seriously ill.
AIDS
• Acquired Immune Deficiency
Syndrome (AIDS) is the name
given to a group of serious
illnesses that are caused by our
body being unable to fight
infection.
• People with HIV or AIDS are more
likely to get some disease and
infections because their immune
system cannot fight them of.
• AIDS is caused by HIV.
HIV and the Immune system
The life cycle of HIV
1. Viral Attachment
2. Viral fusion
3. Uncoating
4. Integration
5. Viral latency
6. Final Assembly
7. Budding
8. HIV Life Cycle
Video.mpg
Immune Response
• Detection of the virus: helper T cells
• Messengers: send signals to B
cells(lymphocytes)
• Mounting an attack ;CD4 cells( helper T
cells)
• Fighting off an infection: B cells and T killer
cells
• Memory: memory cells. CD8 (suppressor
cells)
The effect of HIV on
an individual
Viral
Load
It is during
the clinical
latency
period that
we have the
best chance
to extend the
life of
employees
infected with
HIV.
CD4 Count
AIDS
ARV’s only help in the
final stages.
Progression of HIV Infection to AIDS
Primary
Infection
3-6 weeks Acute HIV
Syndrome
HIV specific immune
response (Serum Antibody
3 months detectable)
1 week-
(Window
1-2
weeks
Period)
Death from
AIDS
2 years
average
AIDS Defining
Illness
10 years
Median
Clinical Latency
HIV Risk
• What is your risk?
– Discussion