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Chromosomes and Mitosis Eukaryotic Chromosomes Made of DNA and protein When a cell is not dividing, chromosomes are long, thin strands of chromatin Function is to pass on traits Structure of chromosome: – Sister chromatids – copied DNA – Centromere – attaches each pair of chromatids Each organism has a characteristic # of chromosomes – Ex. Humans have 46 chromosomes Sexually reproducing organisms have 2 sets of homologous chromosomes w/ same genetic info Mitosis Division of nucleus Occurs in 4 stages: PMAT – Prophase – Metaphase – Anaphase – Telophase http://www.stolaf.edu/people/giannini/flash animat/celldivision/crome3.swf Phase 1: Prophase – Chromosomes become visible – Centrioles move to either side of cell – Spindle fibers form – Chromosomes attach to spindle at centromeres – Nuclear membrane and nucleolus disappear – KEY WORD: PAIR Phase 2: Metaphase – Chromosomes line up along the middle of the cell – KEY WORD: MIDDLE Phase 3: Anaphase – Sister chromatids separate into individual chromosomes – Chromosomes move to either end of the cell – KEY WORDS: APART & AWAY Phase 4: Telophase – Chromosomes uncoil – Nuclear membrane forms around each set of chromosomes – Nucleolus reappears – KEY WORD: TWO NUCLEI Mitosis is followed by cytokinesis – Cleavage furrow in animal cells – Cell plate in plant cells Summary: Results in 2 daughter cells which are identical to the parent cell Form of asexual reproduction Used for growth and repair of tissue Unicellular organisms use it to reproduce