Download Anatomy of the Ear

Anatomy of the Ear
Perry C. Hanavan
Audiologist
Major Divisions of the Ear
Peripheral Mechanism
VIII
Outer Middle Inner
Cranial
Ear
Ear
Ear
Nerve
Central Mechanism
Brain
Question
• Why do we have an outer ear, pinna?
Outer Ear
Virtual Tour of the Ear
Pinna
Pinna
Preauricular Tags
Preauricular Pits
EAM
External
Auditory
Meatus
Cerumen
Q-tips
Function
Microtia
EAM resonance
Anotia
Atresia
Pinna
Function of Outer Ear
•
•
•
•
•
Collect sound
Localization
Resonator
Protection
Sensitive
(earlobe)
• Other?
Pinna
• The visible portion that is
commonly referred to as "the
ear"
• Helps localize sound sources
• Directs sound into the ear
• Each individual's pinna
creates a distinctive imprint
on the acoustic wave
traveling into the auditory
canal
External Auditory Meatus
• Extends from the pinna to the tympanic membrane
– About 26 millimeters (mm) in length and 7 mm in diameter in
adult ear.
– Size and shape vary among individuals.
• Protects the eardrum
• Resonator
– Provides about 10 decibels (dB) of gain to the eardrum at around
3,300 Hertz (Hz).
• The net effect of the head, pinna, and ear canal is that
sounds in the 2,000 to 4,000 Hz region are amplified by 10
to 15 dB.
– Sensitivity to sounds greatest in this frequency region
– Noises in this range are the most hazardous to hearing
Outer Ear Resonance
• Influence of pinna (p)
• Influence of ear canal
(c)
• Combine influence (t)
• At 3000 Hz, the final
amplification (t) is 20
dB
Cerumen
• The purpose of this natural wax:
– Repel water
– Trap dust, sand particles, micro-organisms, and
other debri
– Moisturize epithelium in ear canal
– Odor discourages insects
– Antibiotic, antifungal properties
– Cleanse ear canal
Embryological Development
• External Ear Development
Outer Ear Hearing Disorders
• Outer ear
• CHARGE
• Down Syndrome
– Ears small and low set
• Fetal Alcohol
Syndrome
– Deformed ears
• DiGeorge syndrome
– Low set ears
External Ear Care
Hazardous to health:
• Ear candling
• Swabs
• Foreign objects
Middle Ear
Virtual Tour of the Ear
Middle Ear Cavity
Tympanic Cavity
Tympanic Membrane
Ossicles
Middle Ear Muscles
Eustachian Tube
Mastoid
Ossicles
Middle Ear Muscles
Mastoid
Eustachian Tube
Function
Amplifier
Cholesteatoma
Temporal bone fractures
Otitis Media
PE tubes
Otosclerosis
Function of Middle Ear
• Conduction
– Conduct sound from the outer ear to the inner ear
• Protection
– Creates a barrier that protects the middle and inner areas from
foreign objects
– Middle ear muscles may provide protection from loud sounds
• Transducer
– Converts acoustic energy to mechanical energy
– Converts mechanical energy to hydraulic energy
• Amplifier
– Transformer action of the middle ear
– only about 1/1000 of the acoustic energy in air would be
transmitted to the inner-ear fluids (about 30 dB hearing loss)
Middle Ear
Tympanum
Timpani, or kettledrums, are
musical instruments in the
percussion family. A type of drum,
they consist of a skin called a head
stretched over a large bowl
commonly made of copper. They
are played by striking the head
with a special drum stick called a
timpani stick. Unlike most drums,
they produce a definite pitch when
struck. Timpani evolved from
military drums to become a staple
of the classical orchestra in the
17th century. Today, they are used
in many types of musical
ensembles including classical
orchestra
Tympanic Membrane
• The eardrum separates the outer ear
from the middle ear
• Creates a barrier that protects the
middle and inner areas from foreign
objects
• Cone-shaped in appearance
– about 17.5 mm in diameter
• The eardrum vibrates in response to
sound pressure waves.
• The membrane movement is
incredibly small
– as little as one-billionth of a centimeter
Eustachian Tube
• The eustachian tube connects the front wall of the
middle ear with the nasopharynx
• The eustachian tube also operates like a valve,
which opens during swallowing and yawning
– This equalizes the pressure on either side of the
eardrum, which is necessary for optimal hearing.
– Without this function, a difference between the static
pressure in the middle ear and the outside pressure may
develop, causing the eardrum to displace inward or
outward
• This reduces the efficiency of the middle ear and less acoustic
energy will be transmitted to the inner ear.
Ossicles
• Malleus
(hammer)
• Incus (anvil)
• Stapes
(stirrup)
smallest
bone of the
body
Transformer/Amplifier
• Transform the vibrating motion of the eardrum into motion of
the stapes.
• The middle ear enhances the transfer of acoustical energy in
two ways:
– The area of the eardrum is about 17 times larger than the oval window
• The effective pressure (force per unit area) is increased by this amount.
– The ossicles produce a lever action that further amplifies the pressure
• Without the transformer action of middle ear, about 1/1000 of
acoustic energy in air transmitted to inner-ear fluids (about 30
dB loss).
• Malleus and incus vibrate together, transmitting the sound
waves from the eardrum to the footplate of the stapes (this
pushes the oval window in and out)(mechanical energy)
Transformer/Amplifier
• Area ratio
– Thumbtack
• Lever
– crowbar
Middle Ear Muscles
• Tensor tympani
– Attached to malleus
– Innervated by V, trigeminal nerve
• Stapedius
– Attached to stapes
– Innervated by VII, facial nerve
• Middle Ear Muscle Function:
– Help maintain ossicles in proper position
– Protect inner ear from excessive sound
levels
• When ear exposed to sound levels above
70 dB, the muscles contract, decreasing
amount of energy transferred to inner ear
– This protective reflex termed "acoustic
reflex"
Ligaments of Middle Ear
• Function
– restrict and confine
the effect of ossicles
to act as a lever
– restrict movements to
reduce the chance of
damage to the inner
ear
– prevents distortion to
sound
Mastoid
Development of Middle Ear
• Middle Ear Development
Middle Ear Disorders
• Middle Ear disorders
–
–
–
–
–
–
–
–
–
Acute otitis media
Otosclerosis
Disarticulation
Mastoiditis
Tympanosclerosis
OME
TM Perforation
TM Retraction
Cholesteatoma
• Down Syndrome
• Treacher Collins Syndrome
• BOR Syndrome
Inner Ear
Virtual Tour of the Ear
Vestibular
semicircular canals
Auditory
utricle and saccule
Cochlear
traveling wave
Vestibular
traveling wave
traveling wave
pathologies
Function of Inner Ear
• Convert mechanical sound
waves to neural impulses
that can be recognized by
the brain for:
– Hearing
– Balance
Balance
• Linear motion
• Rotary motion
Cochlea
• The cochlea resembles a
snail shell and spirals for
about 2 3/4 turns around
a bony column
• Within the cochlea are
three canals:
– Scala Vestibuli
– Scala Tympani
– Scala Media
Anatomy of the adult mammalian cochlea
Barald, K. F. et al. Development 2004;131:4119-4130
Organ of Corti
• End organ of
hearing
Organ of Corti
Organ of Corti
OHC vs. IHC Function
OHC Motility Models
Afferent Neural Innervations
Hair Cells
• Outer Hair
Cells
• Inner Hair
Cells
• OHC
movie
OCH Cilia Theory: Tip-links
<<<IHC
OHC >>>
OHC Cilia: Tip-links
OHC Somatic Motility
OHC—With and Without Prestin
• No other cells
except OHC
• Prestin is the
motor protein
of mammalian
OHCs.
• It is highly
expressed in
OHC, and is
not expressed
in nonmotile
IHC.
OHC—With and Without Prestin
About 55 dB
difference
OHC in Prestin
Knockout
Mouse
Traveling Waves
•
•
•
•
Traveling wave
Basilar membrane
Traveling Wave info
Cochlear Traveling Wave
Inner Ear Etiologies
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•
•
•
•
Genetic
Excessive Noise
Head Trauma
Metabolic
Ototoxic
Connexin 26
Noise Trauma
Developmental
• Inner Ear Embryological Development
VIII Cranial Nerve
Virtual Tour of the Ear
Auditory Branch
Auditory Branch
Vestibular Branch
Vestibular Branch
Spiral ganglion
Acoustic Tumors
Standard ABR
Cross-section of Internal Auditory
Canal
Sup. Vest Nerve
Facial Nerve
HIGHFREQUENCY
FIBERS
Acoustic Nerve
Large Tumor
Abnormal Standard ABR
TUMOR
The wave V latency used in the
standard ABR IT5 and I-V delay
measures is dominated by neural
activity from the high-frequency
regions of the cochlea. Thus, unless
the tumor affects these high-frequency
fibers sufficiently, standard ABR
latencies will be normal.
Inf. Vest Nerve
Small Tumor
Abnormal Standard
ABR
Small Tumor
Normal Standard ABR
Acoustic Neuroma
• Tumor
Spiral Ganglion
Acoustic Neuroma
Central Auditory Mechanism
Virtual Tour of the Ear
Auditory Path
Auditory Path
Central Auditory Path
Etiologies
Nonorganic Hearing Loss
• Sometimes referred to as functional,
feigning, etc.
• No physical evidence of hearing loss
• Conscious and unconscious
• Adults: medical/legal reasons
• Children: attention, psychological, reward,
etc.
Development of the otocyst
Barald, K. F. et al. Development 2004;131:4119-4130
Inductive interactions that regulate otocyst induction and ventral patterning
Barald, K. F. et al. Development 2004;131:4119-4130
Development of the cochlear duct and organ of Corti
Barald, K. F. et al. Development 2004;131:4119-4130
Effects of modulating gene expression on development of the organ of Corti (OC)
Barald, K. F. et al. Development 2004;131:4119-4130
Generation of stereociliary bundle orientation
Barald, K. F. et al. Development 2004;131:4119-4130
Six1 expression during inner ear development
Zheng, W. et al. Development 2003;130:3989-4000