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Overview – Brain • • • • Development Macroanatomy Microanatomy Plasticity Brain - Gross Anatomy 1/3 • Basic subdivisions – – – – Spinal Cord Brain Stem Cerebellum Cerebral Cortex • Conscious thought • Planning • Language Adult Brain - Gross Anatomy 2/3 • Inputs – Neurons with processes extending to the eyes, ears, nose, tongue and skin. • Output – Movement – arms, legs, tongue, lips etc. Adult Brain - Gross Anatomy 3/3 • Other areas of cerebral cortex – – – – Broca’s Wernicke’s Prefrontal Temporal lobe • Hippocampus Adult Brain - Microanatomy 1/2 • Neurons – Receiving - dendrites – Sending – axons • Can be very long • Can be covered with a fatty substance • Connections between neurons – Chemical released by one neuron – Same chemical is “sensed” by next neuron – Chemicals may vary depending on which neuron is sending the information. Adult Brain - Microanatomy 2/2 • Connections between neurons – Chemical released by one neuron – Same chemical is “sensed” by next neuron – Chemicals may vary depending on which neuron is sending the information. – Chemical process and result of chemical processes can be affected by subcortical activity. What?? So what. I want to know how the someone learns! 1/2 • Connections between areas are pretty much fixed • A particular neuron may be connected to 100s of neurons in another or the same region. How the brain learns! 2/2 • The connections of given sets of cells cause a group of cells to be active (network) and that particular network represents an idea, object, word. • Badly formed networks or randomly active cells can lead to problems in how a particular network is recognized. e.g. inability to identify or produce sounds, syllabi or sentences. • Previous network activation can influence which networks are subsequently activated (context). Now I know why someone doesn’t know something but how does one learn? • Connections between cells can be changed and therefore new networks can be established. (weights) • Changes are the result of repetition within a particular context. • The larger and more distinctive the context, the easier it is to learn. • Be wary of interference! Developing Brain and Language • During development gross connectivity can be affected by environment, genetics, or chemicals. • Connections in the developing brain are the result of physical cues and activity caused by the environment. • Fine tuning of connections can only occur after the major connections have been established. Delayed Plasticity • Behavioral level • Gross Anatomy level • Microanatomical level • Functional Plasticity • Continuum Extra References • http://www.bbsonline.org/documents/a/00/ 00/04/95/bbs0000049500/bbs.pulvermueller.html • Digital Anatomist: http://www9.biostr.washington.edu/cgibin/DA/imageform