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9 How Nerve Signals Maintain Homeostasis 9.1 The Importance of the Nervous System 9.1: The Importance of the Nervous System • The nervous system is an elaborate communication system that has more than 100 billion nerve cells in the brain alone. • Memory, learning and language are all a part of the nervous system. • Has two divisions: the central nervous system (CNS) and the peripheral nervous system (PNS). Vertebrate Nervous System Central nervous System (CNS): • The nerves in the brain and spinal cord Peripheral Nervous System (PNS): • Nerves that carry info. Between the organs and the CNS • CNS is all the nerves of the brain and spinal cord and is the coordinating centre for incoming and outgoing information. • The PNS include the nerves that carry information between the organs of the body and the CNS – PNS can be divided further into the somatic and autonomic nerves. • Somatic: controls the skeletal muscle, bones and skin. • Autonomic: special motor nerves that control the internal organs of the body. – Autonomic can be subdivided into the sympathetic and the parasympathetic. Peripheral Nervous System Somatic Nerves: • Controls skeletal muscles, bones and skin • Brings information from the external environment to the CNS • Motor somatic nerves What do the somatic nerves control? Controls the skeletal muscles Peripheral Nervous System Autonomic Nerves: • Motor nerves that control organs Is this sensory, integrative, or motor input? SENSORY – monitor: • temperature, light, and sound, ETC. – Inside the body receptors detect variations in: • pressure, pH, carbon dioxide concentration, and the levels of various electrolytes. Is this sensory, integrative, or motor input? – signals are brought together to: • create sensations, to produce thoughts, or to add to memory. – Decisions are made based on the sensory input. This is integration. Integrative Is this sensory, integrative, or motor input? – nervous system responds by: • sending signals to muscles, causing them to contract, or to glands, causing them to produce secretions. – muscles and glands are called effectors • they cause an effect in response to directions from the nervous system. – This is the motor output or response motor input Anatomy of a Nerve Cell Glial Cells: • Structural support and metabolism of nerve cells • Non-conducting Neurons: • Sensory neurons • Interneurons • Motor Neurons Sensory Neurons • Afferent neurons • Sense and relay stimuli (information) from the environment to the CNS • Located in clusters outside of the spinal cord Interneurons/Association Neurons • Neurons that link together neurons in the body • Mainly in the spinal cord and brain • human brain contains ~100 billion (1011) interneurons averaging 1000 synapses on each or some 1014 connections Motor Neurons • Efferent Neurons • Relay information to the effectors – Muscles, organs and glands – The axons connecting your spinal cord to your foot can be as much as 1 m long (although only a few micrometers in diameter). What are the three parts of all neurons? 1. Dendrites 2. The cell body 3. The axon Neuron Structure Dendrites: • Receive information • Conduct nerve impulses toward the cell body Axon: • Sends nerve impulses from the cell body to other neurons (effectors) Myelin Sheath: • White coat of fatty protein that covers some axons Neuron Structure Schwann Cells: • Individual cells that compose the myelin sheath • Insulates the nerve cell Nodes of Ranvier: • Areas between the sections of myeline sheath ANIMATIONS • http://www.sumanasi nc.com/webcontent/ anisamples/neurobi ology/neurobiology.h tml The Speed of Nerve Impulses • Myelinated nerve fibres speed up nerve impulses • Nerve impulses jump from one node to another… speeding up nerve action Reflex Arcs • What are the 3 overlapping nervous system functions? –Sensory –Integrative –Motor • Does this describe the autonomic or somatic nervous system? – Control the internal organs of the body – operate without conscious control – constant interplay of balance between sympathetic and parasympathetic autonomic nerves http://itc.gsw.edu/faculty/gfisk/anim/a utonomicns.swf Does this describe the sympathetic nervous system or parasympathetic? – Prepares the body for stress: • increases heart rate, • increases the release of glucose, • dilates the pupils, • increases blood flow to the skin, • causes release of epinephrine • sympathetic nervous system parasympathetic nervous system –Restores normal balance: • decreases heart rate, • stores glucose, • constricts pupils, • decreases blood flow to the skin Neuron Repair Neurilemma: • Thin membrane that surrounds the axon • Promotes regeneration of damaged neurons • Not in all nerve cells White Matter: • Nerve cells in the brain that contain myelinated fibres and a neurilemma Grey Matter: • Nerve cells in the brain and spinal cord that lack a myelin sheath and neurilemma • Why are spinal and brain injuries often permanent? How to Fix “Irreparable” Damage to the CNS 1. Reattach two torn nerves Limited success 2. Grafts from the PNS More successful…CNS cells that are left alone however, had no regeneration Stem Cells • Cells that have not specialized into tissue cells • Experiments are being done on replacing damaged cells using stem cells • E.g. pp. 415…rats with reconnected spinal cords • Page 417 # 1-6