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Cycle of Infection HST I Objectives / Rationale •Infection Control is an increasingly important aspect of health care for the client and the health care professional. • Upon completion of this lesson, the student will be able to: • Identify the cycle of the infectious process; • Investigate ways to protect themselves and patients from infection; and • Research common human pathogens. Infections and diseases are classified as: Endogenous – it originates within. Includes: metabolic disorders, congenital abnormalities, tumors, infections from microorganism within the body. Exogenous – originates outside the body; includes invading pathogens, radiation, chemical agents, trauma, electric shock, temperature extremes. • Nosocomial – is one that is acquired in a health care facility, which is transmitted by health care workers to the patient. • Opportunistic – those that occur when the body’s defenses are weak; i.e. weakened immune system. Infections are also: • Aerobic – the organism requires oxygen to live. • Anaerobic – the organism lives and reproduces in the absences of oxygen. Infection Cycle: • Infective Agent – pathogens include bacteria, viruses, funguses, rickettsiae, protozoa. • Reservoir – where causative agent can live. Includes the human body, animals, environment, and fomites or objects contaminated with infectious material that contains the pathogens. • Portal of exit – way for causative agent to escape from the reservoir. • Pathogens can leave the body through urine, feces, saliva, blood, tears, mucous discharge, sexual secretions, draining wounds. • Means of transmission – how it is transmitted to another host. • By: Direct Contact – person to person, physical contact, or contact with body secretions containing the pathogen. • Indirect Contact – from contaminated sources such as food, air, soil, equipment, etc. • Indirect contact can include touching contaminated equipment or surfaces, breathing in droplets carrying airborne pathogens, or receiving the bite of an insect carrying the pathogen. • Portal of entry – way to enter a new reservoir or host. • Breaks in the skin or mucous membrane; respiratory tract; digestive tract; genitourinary tract; circulatory system. • Susceptible host – individual who can contract the disease, unless: • Defense mechanisms are intact. • Immune system is functioning. The cycle of infection can be broken: • The infectious agent can be neutralized or destroyed by treatment. • The reservoir host must maintain personal hygiene. • The portal of exit is closed by the use of proper attire (gowns, gloves, etc), control of body secretions, proper handwashing. • The route of transmission is minimized through proper handwashing, disinfection, sterilization, and proper disposal of contaminated materials. • The portal of entry is blocked by asepsis, disinfection, and sterilization procedures. • Health and wellness of the individual is maintained. Microorganisms and Disease • Microorganism – an organism that is too small to be seen by the human eye. • Fungi – simple plants such as molds and yeasts • Protozoa – only group classified as an animal. • Virus – cannot be seen by ordinary microscope; not destroyed by antibiotics. • Bacteria – classification is determined by the shape of the bacteria and whether it grows with or without oxygen. Only a few, such as staphylococcus and streptococcus cause disease. • Cocci – round; includes staphylococci which is in clusters like grapes; causes boils, impetigo and osteomyelitis. • Cocci also includes streptococci, round bacteria arranged in chains; causes rheumatic fever, streptococcal pneumonia, and scarlet fever. • Cocci also includes diplococci, arranged in pairs – causes gonorrhea and meningitis. • Bacilla (i) – rod-shaped bacteria. • Spirilla – bacteria shaped like spirals. • Rickettsiae – smaller than bacteria; barely visible under microscope. Causes typhus, Rocky Mountain Spotted Fever. • Pathogen – the term for a diseasecausing microorganism. Vocabulary terms: • Sterile means “free from all organisms”, including spores and viruses. • Contaminated – organisms and pathogens are present. Asepsis – the absence of infection • Medical Asepsis – practices and techniques designed to protect individuals from the spread of disease. • Antiseptic – substances that inhibit the growth of bacteria. Some can be used on the skin. • Disinfectant – cannot be used on skin; includes chemicals and boiling. Sterile – absence of all microorganisms • Surgical asepsis – the use of sterile technique to handle equipment, maintain sterile fields, change dressings, and dispose of contaminated materials without introducing harmful microorganisms. Sterilizing with an Autoclave • The autoclave is the safest, most efficient sterilization method. • An autoclave is a piece of equipment that uses steam under pressure or gas to sterilize equipment and supplies. • It will destroy ALL microorganisms, both pathogenic and nonpathogenic, including spores and viruses. Using an autoclave • Items that are to remain sterile must be wrapped before they are Items are cleaned and prepared before being put in autoclave. • autoclaved. • Autoclave indicators are used to insure sterility of the item. Using chemicals for ‘disinfection’ • Since many chemicals do not kill spores and viruses, chemicals are not a method of sterilization. • Chemicals are used to disinfect instruments that do not penetrate body tissue. • Examples: 90% isopropyl alcohol, formaldehyde-alcohol; 10% bleach; Lysol, Cidex. Epidemiology • Tracing the occurrence of health related events in society. • Epidemiologist – a person who specializes in the study of outbreaks of diseases within a population group. • Endemic – the ongoing presence of a disease within a population, group or area. Example: the common cold. • Epidemic – a sudden and widespread outbreak of a disease within a population, group or area. Example: a widespread outbreak of measles or influenza. • Pandemic - an outbreak of a disease occurring over a large geographic area, possibly worldwide. Ex: AIDS, H1N1 flu.