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Chapter 4 Principles of Infection Control Objectives Define health careassociated infections and state how often they occur. Describe why infection control is important in respiratory care. Identify and describe the three elements that must be present for transmission of infection within a health care setting. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 2 Objectives (cont.) List the factors associated with an increased risk of a patient acquiring a nosocomial infection. State the three major routes for transmission of human sources of pathogens in the health care environment. Describe strategies to control the spread of infection in the hospital. Describe how to select and apply chemical disinfectants for processing respiratory care equipment. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 3 Objectives (cont.) Describe equipment handling procedures that help prevent the spread of pathogens. State when and to use general barrier measures during patient care. Describe surveillance with regard to infection control. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 4 Infection Control Introduction Hospital-acquired infections (HAIs) account for 2 million infections and 90,000 excess deaths annually. About 5% of all patients admitted develop an HAI. About 25% of mechanically ventilated patients develop pneumonia, and 30% (of those 25%) will die. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 5 Infection Control (cont.) Introduction (cont.) Infection control procedures aim to Eliminate the sources of infectious agents Create barriers to their transmission Monitor the effectiveness of control All health care workers must take responsibility and follow procedures carefully. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 6 Spread of Infection Three elements must be present for infection to spread: Source of pathogens Susceptible host Route of transmission Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 7 Spread of Infection (cont.) Sources of Infectious Agents Humans are the primary source. Inanimate objects (e.g., contaminated medical equipment) can spread infection. Individuals in the hospital capable of being the source include workers, visitors, and patients. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 8 Spread of Infection (cont.) Susceptible Hosts Resistance to infection varies greatly from one person to the next. Host factors that increase the chance of infection are Poorly controlled diabetes Increased age Chemotherapy Placement of tubes and catheters Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 9 Spread of Infection (cont.) Nosocomial Infections are those acquired in the hospital. Most nosocomial pneumonias occur in patients having chest or abdominal surgery. Those with a history of COPD, cigarette smoking, or obesity and with advanced age have the greatest risk for nosocomial pneumonia following major surgery. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 10 Modes of Transmission Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 11 Transmission Routes Contact Transmission – Direct – body susrface to body surface contact. • Touching a pt with your hands • Changing a dressing • Any procedure requiring contact Indirect Contact – occurs between a host and inanimate object such as: • Clothing • Dressings • Instruments • equipment Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 12 Transmission Routes Droplet Transmission – Large contaminated droplets released into the air by coughing, sneezing or talking Can travel 3 feet Influenza and rubella are spread this way Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 13 Transmission Routes Airborne Transmission – Pathogen can be spread through the air on dust. Fungal infections are commonly spread this way. Droplet nuclei are very small particles that remain suspended for long periods of time • Example: TB or measles Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 14 Transmission Routes Vehicle Transmission – Pathogens are transmitted by food or water Examples: Hep A and Salmonella Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 15 Transmission Routes Vector Borne Transmission – Transmission by insect Examples: • West Nile Virus • Malaria Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 16 Spread of Infection to Lungs 3 Ways: Aspiration of oral or gastric secretions Inhalation of infected materials Spread of infection to the lung by the blood (sepsis). Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 17 Infection Control Strategies 1. 2. 3. Decreasing host susceptibility Immunizations and chemoprophylaxis Eliminating the source of the pathogens Interrupting routes of transmission Special equipment handling Barrier/isolation precautions Disposable equipment Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 18 Decrease Host Susceptibility Focus on employee immunization Vaccines include: influenza, hepatitis, diphtheria, tetanus and sometimes TB Due to contact with body fluids, employees and students must be vaccinated against Hepatitis. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 19 Disinfection and Sterilization Cleaning Cleaning is the first step in all equipment processing. It involves removing dirt and organic material. Failure to clean equipment properly can render all subsequent processing efforts ineffective. Soaps and detergents need to be used. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 20 Disinfection and Sterilization (cont.) Disinfection Disinfection destroys the vegetative form of all pathogens except bacterial spores. Disinfection can involve either chemical or physical methods. Pasteurization is the most common physical method. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 21 Disinfection and Sterilization (cont.) Chemical Disinfection Chemical disinfection involves the application of chemical solutions to contaminated equipment or surfaces. Equipment must be immersed in the solution for a set period of time. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 22 Disinfection and Sterilization (cont.) Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 23 Levels of Chemical Disinfection Low Level • 5% acetic acid (vinegar) in a 1:3 solution. • This is often used at home to disinfect equipment • Kills most bacteria (including P. aeruginosa) and viruses but not resistant bugs or spores. • Can also use “quats” – cationic detergents that kill everything except spores and TB. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 24 Levels of Chemical Disinfection (con’t) Intermediate Level Kill all bacteria and fungi but have variable effects on spores and some viruses. 70% ethyl and 90% isopropyl spray for electrical equipment, stethoscopes and skin preps. Iodopher (Providone or Betadyne) skin prep prior to blood draw or IV insertion. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 25 Levels of Chemical Disinfection (con’t) High Level Can destroy all microorganisms except spores. Most common is glutaraldehyde. • A cold chemical disinfectant that lasts for only 28 days • Use test strips to confirm strength of solution • Irritation of eyes and hands (always use goggles and gloves) • Won’t damage equipment • Soak equipment for 20 minutes, rinse well and aseptically dry. Household Bleach (Sodium Hypochlorite) • 1:50 dilution for 10 minutes kills everything. • CDC recommends a 1:10 solution for blood spills Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 26 Sterilization The complete destruction of all forms of microbial life. • Comparison of Methods (Table 3-4) on p.49 Incineration – object of no further use Dry Heat – 1-2 hours @ 160˙ to 180˙C Boiling – 30 minutes @ 100˙C Autoclave- steam under pressure (↑P = ↓T) Ionizing Radiation – x-ray and gamma ray Ethylene Oxide – hazardous but effective gas exposure Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 27 Sterilization Destroys all microorganisms Can be achieved with physical and chemical approaches Steam sterilization is most common and easiest. Low-temperature sterilization technologies include ethylene oxide, a colorless and toxic gas. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 28 Equipment Handling Procedures Nebulizers Large-volume nebulizers are often a problem. Small-volume nebulizers can also produce bacterial aerosols. Ventilators and Circuits Circuits pose the greatest risk for infection. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 29 Equipment Handling Procedures (cont.) Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 30 Equipment Handling Procedures (cont.) Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 31 Cleaning If you must clean equipment make sure: Clean in a “dirty” room and move to “clean” room to dry Wear gloves when disassembling and cleaning equipment If electrical, spray with 70% alcohol spray or bactericidal solution and wipe with paper towels Make sure your equipment properly dries to discourage bacterial growth Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 32 Equipment Handling Disposable Equipment An important alternative to continually reprocessing equipment Three major issues Cost Quality Reuse (raises significant safety concerns) Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 33 Preventing Transmission of Infectious Agents Standard Precautions―combines the major features of Universal Precautions and Body Substance Isolation Standard precautions apply to Blood All body fluids Nonintact skin Mucous membranes Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 34 Preventing Transmission of Infectious Agents Respiratory Hygiene 1. 2. 3. 4. 5. Education of patients and employees Posted signs Source control measures (covering your mouth) Hand hygiene Spatial separation (at least 3 feet of space) Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 35 Expanded Precautions 1. 2. 3. 4. Contact precautions Proper use of gowns and gloves Droplet precautions (see Box 4-11) Airborne infection isolation Use of N-95 respirator when in patient room Protective environment Used with allogeneic stem cell transplant patients Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 36 Expanded Precautions (cont.) Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 37 Personal Protective Equipment Gloves―protect both patients and health care workers from exposure to pathogens Mouth, nose, eye, and face protection―mucous membranes are vulnerable NIOSH-approved N-95 respirator―intended for diseases transmitted by airborne route Gowns and aprons―when contact with blood and body fluids is likely Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 38 Surveillance An ongoing process of monitoring patients and personnel for the acquisition of infection in the health care setting An infection control committee establishes surveillance policies and an infection control expert administers them. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 39 Most Important barrier against spread of infection…. http://www.youtube.com/watch?v=Rc6QRM9 F3IY Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 40