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Download erythema nodosum - Dr. Raj Kumar Sharma
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Transcript
ERYTHEMA NODOSUM • DEFINITION-THIS IS A REACTVE DERMATOSIS THAT • • • OCCERS IN RESPONSE TO A MYRIAD OF CONDITION CHARACTERISED BY TENDER, ERYTHEMATOOUS SUB CUTANEOUS NODULES PRIMARILY AFFECTING THE LOWER EXTREMITIES MOST COMMEN TYPE OF PANNICULITIS AGE 20 TO 30 YEARS BUT ANY AGE GROUP MAY BE AFFECTED FEMALE:MALE 3-6 :1 ETIOLOGICAL AGENTS • BACTERIAL• STREPTOCOCCAL INFECTION, • • • • • • • TUBERCULOSIS,YERSINIOSIS,BRUCELLOSIS,SALMONELL A FUNGAL INFECTION – COCCIDIOIDOMYCOSIS,BLASTOMYCOSIS,HISTOPLASMO SIS, DERMATOPHTOSIS VIRAL INFECTION– INFECTIOUS MONONUCLEOSIS, ORF, HEPATITIS-B HERPES SIMPLEX PARASITIC INFESTATION - AMEBIASIS, GIARDIASIS, DRUGS – SULFONAMIDES,BROMIDES,IODIDES,ORAL CONTRACEPTIVE, MINOCYCLINE,SALISYLATES MALIGNANCIES – HODGKIN’S, NON HODGKIN;S LYMPHOMAS SARCOIDOSIS INFLAMMATORY BOWEL DISEASE,ULCERATIVE COLITIS,CRON’S DISEASE,BECET’S DISEASE CLINICAL PRESENTATON • • • • • • • • • • • • SUDDEN ONSET SYMMETRICAL PAINFUL ERYTHEMATOUS WARM NONULCERATED NODULES/PLAQUES KNEES, SHINS,FEET MAY BE AT THIGHS,ARMS, & FACE UNDERGO COLOUR CHANGES AS ADVANCE IN THE DURATION RESOLVE WITHOUT SCARRING OR ATROPHY ASSOCIATED WITH PYREXIA,MALAISE, HEADACHE ARTHRALGIAS RECURRENT EPISODES ARE KNOWN ERYTHEMA NODOSUM ERYTHEMA NODOSUM HISTOPATHOLOGY • SEPTAL PANICULITIS WITHOUT VASCULITIS TREATMENT • TREATMENT OF UNDERLYING DISEASE • SPONTANEOUSLY RESOLVES • NONSTEROIDAL ANTI-INFLAMMATORY AGENTS- ASPIRIN, INDOMETHACINE,NAPROXEN • ORAL POTASSIUM IODIDE 400 TO 800 MG/DAY • ORAL PREDNISONE
