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Circulatory System • Every single living cell in the body needs a supply of oxygen and nutrients for energy, growth, repair, and heat production. • Each organ has it’s own separate circuit of an artery and vein which branch into smaller vessels and are linked by capillaries. • This individual circuit ensures that every part of the body receives a rich supply of nutrients. • In this way not all of the blood goes to each organ in turn. If this were the case then the furthest organ from the heart would receive no fresh blood. • The only organ to receive all of the blood is the lungs so that all the blood is oxygenated. Circulatory System • The Heart: A muscular pump that pumps blood around the body through a system of vessels • Blood Vessels: These transport blood around the body that is Arteries, veins & capillaries • Blood: Carries important substances to and from the cells in the body through the blood vessels. That is plasma, white blood cells, red blood cells & platelets • Lymphatic system: this is the body’s secondary line of defense, stops the build up of toxins and excess fluid in the body COMPOSITION OF BLOOD RED BLOOD CELLS • Transport of gases – mainly oxygen WHITE BLOOD CELLS • Fight infection PLATELETS • Clotting PLASMA • Transport – mainly carbon dioxide, hormones, nutrients and waste products Circulatory System • The circulatory system is the body’s transport system • The system is made up of the heart, blood, blood vessels and lymphatic system • Blood carries important substances to the cells in the body • Blood carries waste products away from the cells to the excretory organs • Blood is transported in blood vessels called arteries, veins and capillaries • The heart is a muscular pump, which forces the blood around the body, through the blood vessels, in a constant circuit FUNCTIONS OF BLOOD TRANSPORT • • • Red blood cells contain haemoglobin which carries oxygen from the lungs to cells of the body Carbon dioxide is carried from cells to the lungs Plasma – liquid consisting mainly of water – carries nutrients (glucose, amino acids, vitamins, minerals), gases, waste products and hormones DEFENCE • White blood cells digest micro-organisms (which invade the body) and help fight infection CLOTTING • Platelets form a clot over damaged skin, which prevents further blood loss REGULATION • • Blood absorbs heat, which is produced by the muscles and liver and transports it around the body to maintain a constant internal temperature Blood helps regulate the body’s pH balance Blood Clotting The process that prevents blood from clotting in an undamaged vessel is a complex one. Once a vessel has been damaged, platelets adhere to the damaged area forming a plug the plasma protein fibrinogen is converted into fibrin that creates fibres to radiate from the platelets forming a network which traps red blood cells. This blood clot stops further blood loss and prevents entry of bacteria. Once the clot has dried it shrinks to form a scab, which protects the tissues underneath while healing takes place. Heparin is a protein normally present in the blood, which is formed in the liver and it’s function is to prevent blood clotting in the vessels – it is called an anti – coagulant. BLOOD VESSELS ARTERIES VEINS CAPILLARIES Direction Carry blood away from the heart Carry blood towards the heart Link arteries and veins Blood Type Carry oxygenated blood Carry deoxygenated blood Responsible for tissue fluid exchange in cells Structure Thick, muscular elastic walls Less thick walls, contain valves which prevent back flow of blood Walls are very thin - only one cell thick to allow the process of diffusion Pressure Blood is carried under high pressure Blood is carried under low pressure Blood pressure is higher at arterial side Location Generally deep seated – except pulse areas Generally superficial Form networks in tissues Divisions Divide into smaller vessels called arterioles which deliver blood to capillaries Divide into smaller vessels called venules which continue from capillaries Smallest blood vessels Tissue fluid Exchange Blood rich in oxygen and nutrients is transported around the body at high pressure via the arteries. The arteries divide into smaller and smaller vessels until they become capillary networks in the tissues. Fluid escapes thorough the thin walls of the capillaries, bathing the cells delivering nutrients and oxygen in exchange for waste products. Tissue fluid Exchange The tissue fluid passes back through the capillary walls into the venous side of the capillary network, where the pressure is lower. Any left over fluid and molecules too large to go Through the blood capillary, pass into the lymphatic capillary and now becomes lymph fluid. TISSUE FLUID EXCHANGE Capillary LYMPHATIC SYSTEM • The lymphatic system is the body’s secondary line of defence (immunity) • Prevents the build up of toxins and excess fluid in the body • Consists of lymph fluid, lymph nodes, lymph ducts and lymph vessels • The lymphatic system is part of the circulatory system • The lymph fluid contains waste products – this fluid is transported by lymph vessels (which also have valves) • The fluid is then filtered by the lymph nodes and then returned back to the venous system by the lymph ducts THE LYMPHATIC SYSTEM The lymphatic system is really part of the vascular system – the blood is contained in a closed system of vessels which is kept circulating by the heart, from the capillaries some fluid escapes called plasma, this is by diffusion and filtration. This fluid then bathes the tissues directly, when this fluid is collected into the lymph vessels it becomes lymph, which is later returned to the blood stream. Lymph vessels start as fine, blind ended lymph capillaries which then join to form lymphatics which are similar in general course and structure to that of veins. THE LYMPHATIC SYSTEM They are semilunar and numerous through and have many more finer (pocket) valves, this is because the lymph is not pumped by the heart. The composition of lymph is similar to blood plasma but has less protein, less food materials and more waste material – it has no erythrocytes but has More leukocytes. THE LYMPHATIC SYSTEM Lymph drainage is through lymph nodes – before the lymph can be returned to the blood stream it is filtered through one or more of the lymph nodes, which are bean shaped structures, situated at strategic points in the course of the lymph vessels. THE LYMPHATIC SYSTEM After passing through the nodes the lymph is then collected into the main lymph vessels – vessels – lymph from the right side of the head and thorax and right arm, drain into the right lymphatic duct, while lymph from the rest of the body drains into the thoracic duct. THE LYMPHATIC SYSTEM The lymphatic system acts as the body’s secondary line of defence against bacterial invasion, this is through the presence of leukocytes at the site of infection. BODY LYMPHATIC SYSTEM PAROTID Buccal Lymph Nodes SUBMANDIBULAR CERVICAL UPPER & LOWER Thoracic Lymph Nodes SUBMENTAL Axillary Lymph Nodes Abdominal Lymph Nodes Iliac Lymph Nodes Inguinal Lymph Nodes Papliteal Lymph Nodes THE HEART RATE – PULSE The left ventricle contracts so strongly that it can be felt as a pressure wave or ‘pulse’ at certain places along an artery where the artery is nearer the surface of the skin. Measuring your pulse: • The pulse can be felt strongly in two main places – the neck and the wrist. • To feel for your pulse you must use two fingers not your thumb as this has a pulse of it’s own. EXPERIMENT 1. Take a measurement of your resting heart rate timed over 30 seconds and then double to find your resting heart rate per minute. 2. To increase you heart rate do some vigorous exercise for 3 minutes or until you are out of breath. 3. After the exercise take you pulse again. 4. How long does it take to go back to your resting heart rate? A healthy adult has a resting pulse rate of 60–80 beats a minute. Someone who is unfit or who has a sedentary lifestyle may have a pulse of 120 beats a minute. A trained athlete or a very fit person may have a pulse of 35-40 beats a minute. THE HEART • • • • • • • • • • • Is a hollow muscular organ ‘pump’ Pumps blood around the body Comprises of 4 chambers Upper chambers = Atria Lower chambers = Ventricles Divided into 2 halves by the septum Left side deals with oxygenated blood Right side deals with de-oxygenated blood Situated in the thoracic cavity Between the lungs – slightly to the left Protected by the rib cage Deoxy, bld(from body) Lungs(oxy) VC PV RA LA LV RV Aorta PA body Aorta (Arch) Superior Vena cava Pulmonary Artery Pulmonary Vein Right Atrium Left Atrium Mitral Valve Tricuspid Valve Inferior Vena cava Right Ventricle Septum Left ventricle CIRCULATION OF BLOOD THROUGH THE HEART Humans and other mammals have a double circulatory system; the blood circulates around 2 separate pathways joined at the heart. The systemic Circulation Or the general circulation, carries oxygenated blood from the heart to parts of the body and back again- (not including the lungs) In both circuits, gases exchange places in the capillary vessels. The pulmonary Circulation Carries blood from the heart to the lungs be oxygenated and back to the heart. CIRCULATION OF BLOOD THROUGH THE HEART The pulmonary Circulation Deoxygented blood comes from the body and travels into the heart’s upper chamber, the right atrium, via the vena cava. The atrium contracts and blood is forced into the right ventricle. The right ventricle contracts and blood passes out of the heart into the Pulmonary artery. The pulmonary artery goes to the lungs where the blood picks up oxygen – this is now oxygenated blood. CIRCULATION OF BLOOD THROUGH THE HEART The systemic Circulation The oxygenated blood travels from the lungs via the pulmonary vein to the left atrium of the heart. The left atrium contracts and blood is forced into the left ventricle. The left ventricle contracts and blood passes out of the heart via the Aorta. The oxygenated blood is transported around the body through arteries that branch from the main artery - aorta. BLOOD CIRCULATION Label the following on diagram (use the letters as key) A – a blood vessel rich in oxygen B- a blood vessel low in oxygen C- a blood vessel rich in carbon dioxide D- a blood vessel low in carbon dioxide E- a blood vessel under high pressure F- a blood vessel under low pressure G- a blood vessel that has valves C B G F D A E Subclavian Jugular Vena Cava Axillary Cephalic Brachial Basilic Median Great Saphenous Radial Femoral Popliteal Short Saphenouse Anterior Tibial Vein Posterior Tibial Vein Subclavian Carotid Axillary Aorta Brachial Radial Iliac ulnar Deep Palmer Arch Superficial Palmer Arch Femoral Digital Arch Popliteal Anterior Tibial Posterior Tibial Blood Groups There are four different blood groups, A, B, AB & O. Blood from one individual cannot always be safely mixed with that of another, this is due to the two types of protein that may be present on the red blood cells – A and B. These proteins are Antigens to individuals who lack them. Antigen – any substance that the body regards as foreign or potentially dangerous and against which it will produce an antibody. Antibodies - are found in the plasma and can cause the red cells of other groups to clump together and can be fatal as the clumps of red cells block the blood vessels and obstruct the circulation – this is called Agglutination – (can also cause kidney damage). The antibodies are called Agglutinins. *Agglutinated cells block the flow of blood disrupting circulation and the distribution of O2, gases and nutrients Blood Groups Blood group A B AB O Agglutinogen Agglutinin (Antigen on (antibody in RBC) plasma) A Anti - B B Anti - A A+B None None Anti A + Anti B Blood Groups Transfusion Considerations Doner / Recipient A A B B AB X X X X Universal Recipient AB O O X X X Universal Donor The Rhesus Factor In addition to ABO grouping there is another antigen present in the blood of about 85% of the population-it is known as the Rhesus Factor, (named after the group of monkeys it was discovered in). Those who have this factor are known as Rhesus + positive) – 85% Mother-fetus incompatibility Normally, anti-Rh+ antibodies do not exist in the first-time mother unless she has previously come in contact with Rh+ blood. Therefore, her antibodies are not likely to agglutinate the red blood cells of her Rh+ fetus. Rh (Rhesus) Factor • Up to 8 genes determine if a person is Rh positive. • The most common of these are the C, D & E genes which determine if a person has C, D and/or E antigens on the walls of the cells. • People who do not have Rh antigens on their cell membranes are Rh negative. BLOOD SUPPLY TO THE HEAD AND NECK VESSEL AREA SUPPLIED/DRAINED Internal carotid artery Supplies blood to brain and eyes External carotid artery Main vessel supplying book to upper part of neck/face – subdivides into branches supplying other areas: facial, occipital, temporal Facial artery Supplies upper/lower and facial muscles Superficial temporal artery Supplies the face by its transverse (across) facial branch Occipital artery Supplies upper part of the neck and back of scalp Internal jugular vein Brains blood from brain External jugular vein Main vessel draining blood from face/neck – blood is supplied to it by smaller veins which drain different area Facial vein Drains front of scalp and superficial structures of the face Retromandibular vein Drains face below jaw and back of scalp Blood Pressure The blood pressure is the amount of pressure exerted on an arterial wall due to the contraction of the left ventricle. The pressure in the arteries varies during each heartbeat. The maximum pressure of the heartbeat is known as the systolic Pressure and represents the pressure exerted on the arterial wall during active ventricular contraction. Systolic pressure can therefore be measured when the heart muscle contracts and pushes blood out into the body through the arteries. The minimum pressure, or diastolic pressure, represents the static pressure against the arterial wall during rest or pause between contractions. Therefore the minimum pressure is when the heart muscle relaxes and blood flows into the heart from the veins. Superficial Temporal Artery Occipital Artery & Vein Retromandibular vein Facial Artery Facial Vein Jugular Vein Carotid Artery PAROTID SUBMANDIBULAR SUBMENTAL CERVICAL UPPER & LOWER LYMPH SUPPLY TO THE HEAD AND NECK – ANSWER GUIDE NODES/DUCT/VESSEL AREA DRAINED Submental Nodes Drain lymph from chin Submandibular Nodes Drain lymph from middle of cheeks Parotid Nodes Drain lymph from sides of cheeks and forehead Thoracic Duct Main collecting duct – collects lymph from left side of head and neck, left arm, lower limbs and abdomen. Left Subclavian Vein Lymph from thoracic duct drains into this vein Right Lymphatic Duct Very short in length – collects lymph from right side of head and neck and right arm Right Subclavian Vein Lymph from right lymphatic duct drains into this vein