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3.034 Materials Biology Nano Life at the interface Motivation for 3.034 Use principles of Materials Science and Engineering to solve bio-related problems Use Biochemistry and Biology to create new materials S P NH2 biosensors E GRGDSPC O S S C C C H2 H2 surface modification N H NH2 Toolbox of Materials Science and Biochemistry Synthetic polymers • polyesters Reactions • Nucleophilic substitution • Coupling chemistry • Protection chemistry Secondary interactions • polyamides • H-bonds • polycarbonates • hydrophobic interactions • polyurethane-ureas • electrostatic interactions • biodegradable polymers • π- π conjugation • conducting polymers Biomolecules • amino acids, peptides, proteins Nanomaterials • enzymes • Carbon nanotubes • antibodies • gold nanoparticles • DNA • semiconductor nanoparticles • lipids