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Transcript
Section Objectives: 18.1
• Identify the different kinds of viruses
and their structures.
• Compare and contrast the replication
cycles of viruses.
• You’ve probably had the flu—influenza—at
some time during your life.
• Nonliving particles called _______
cause influenza.
• Viruses are composed of _____ ______
enclosed in a ______ coat and are smaller
than the smallest bacterium.
• Most biologists consider viruses to be
_______ because they don’t exhibit all
the ______ for life.
• They don’t carry out respiration, grow, or
develop. All viruses can do is _______—make
copies of themselves—and they can’t even do
that without the help of living cells.
• A cell in which a virus replicates is
called the _____cell.
• Viruses, such as _____ viruses and _____
viruses, were named after the diseases they
cause.
• Other viruses were named for the _____ or
______ they infect.
• Today, most viruses are given a ______
name ending in the word “virus” and a
______ name.
• However, sometimes scientists use ____
numbers to distinguish among similar
viruses that infect the same ____.
• A virus that infects a bacterium is called
a __________ (bak TIHR ee uh fayj), or
phage for short.
Capsid
Nucleic
acid
• A virus has an
inner core of
nucleic acid,
either ___ or
___, and an outer
protein coat
called a ____.
Envelope
Capsid
• Some relatively
large viruses, such
as human ___
viruses, may have
Nucleic
an additional
acid
layer, called an
_______,
surrounding their
Envelope
capsids.
Capsid
Nucleic
acid
Envelope
• Envelopes are
composed
primarily of the
same materials
found in the
______
membranes of all
cells.
Nucleic acid
• ___ nucleic acid is either
DNA or RNA and
contains instructions for
making copies of the
virus.
• Some viruses have only
four _____, while
others have hundreds.
Capsid
Nucleic acid
• The _____ _____ virus
has a long, narrow
_______ shape.
Capsid
Capsid
Nucleic acid
• The arrangement of
_____ in the capsid
of a virus
determines the
virus’s _____.
• ________ viruses
resemble small
crystals.
Capsid
Nucleic acid
• The protein
arrangement also
plays a role in
determining what
cell can be
_______ and how
the virus infects
the cell.
• Before a virus can replicate, it must
____ a host cell.
• A virus recognizes and ______ to a
host cell when one of its ______
interlocks with a molecular shape that
is the ______ site on the host cell’s
plasma membrane.
Capsid
Nucleic
acid
Tail
Tail fiber
• A protein in the
___ fibers of the
bacteriophage __
recognizes and
attaches the T4 to
its bacterial host
cell.
Capsid
Nucleic
acid
Tail
Tail fiber
• In other viruses, the
attachment protein is
in the ____ or in the
envelope.
• Each virus has a ________ shaped
attachment protein. Therefore, each
virus can usually attach to only a few
kinds of cells.
• In general, viruses are species specific,
and some also are ____-type specific. For
example, polio viruses normally infect
only intestinal and nerve cells.
• The species specific characteristic of
viruses is significant for controlling
the spread of _____ diseases.
• Once attached to the plasma membrane
of the host cell, the virus _____ the cell
and takes over its ________.
• Only then can the virus ________.
• Viruses have ____ways of getting
into host cells.
• The virus may _____its nucleic acid
into the host cell like a syringe injects
a vaccine into your arm.
• The _____ of the virus stays attached
to the outside of the host cell.
• An ________ virus enters a host
cell in a different way.
• After attachment, the plasma membrane
of the host cell surrounds the virus and
produces a virus-filled vacuole inside
the host cell’s cytoplasm.
• Then, the virus bursts out of the
vacuole and releases its nucleic
acid into the cell.
• Once inside the host cell, a virus’s
genes are _________ and the
substances that are produced take over
the host cell’s genetic material.
• The ____ genes alter the host cell
to make new viruses.
Bacteriophage
Nucleic
acid
Bacterial DNA
Bacterial
host cell
A. Attachment
B. Entry
The bacteriophage
injects its nucleic acid
into the bacterial cell.
E. Lysis and Release
The host cell breaks open and
releases new virus particles.
D. Assembly
New virus particles
are assembled.
C. Replication
The host’s metabolic
machinery makes viral
nucleic acid and proteins.
• The host cell uses its own _______, raw
materials, and energy to make copies of
viral genes that along with viral proteins
are assembled into new viruses, which
_____ from the host cell, killing it.
• The new viruses can then infect and kill
other host cells. This process is called a
____ (LIH tik) _____.
• Not all viruses ____ the cells they infect.
• Some viruses go through a ________
cycle, a replication cycle in which the
virus’s nucleic acid is ________ into the
host cell’s chromosome.
• A ________ cycle begins in the same way
as a lytic cycle.
• However, in a lysogenic cycle, instead of
_________ taking over the host’s genetic
material, the viral DNA is integrated into
the host cell’s chromosome.
• Many disease-causing ______ have
lysogenic cycles.
• Three examples of these viruses are
____ _____ I, herpes simplex II that
causes ______ herpes, and the _______
B virus that causes hepatitis B.
• Another lysogenic
virus is the one that
causes _____ ___.
• Having chicken pox, which usually
occurs before age ten, gives lifelong
protection from another infection by
the ___. However, some chicken pox
viruses may remain as _________ in
some of your body’s nerve cells.
• Later in your life, these proviruses
may enter a lytic cycle and cause a
disease called _______—a painful
infection of some nerve cells.
• Either lysis, the bursting of a cell, or
______, the active transport process by
which materials are expelled from a cell,
release new viruses from the host cell.
• In exocytosis, a newly produced virus
approaches the inner surface of the host
cell’s _______ membrane.
• The plasma membrane surrounds the virus,
enclosing it in a _____ that then fuses with
the host cell’s plasma membrane.
• Then, the ______are released
to the outside.
• Many viruses, such as the _____
_______________ ____(HIV) that causes
the disease AIDS, are RNA viruses—RNA
being their only nucleic acid.
HIV virus
• Once inside a
human host,
HIV infects
_____ blood
cells.
Normal white blood cells
• Newly made viruses are released
into the blood stream by ________
and infect other white blood cells.
• Infected host cells still function
normally because the viral genetic
material is a ______ that produces
only a small number of new viruses
at a time.
• Because the infected cells are still able to
function normally, an infected person may
not appear _____, but they can still ____
the virus in their body fluids.
• Most people with an HIV infection
eventually get ____ because, over
time, more white blood cells are
infected and produce new viruses.
• Because white blood cells are part of a
body’s ______-fighting system, their
destruction interferes with the body’s
ability to protect itself from organisms
that cause disease, a symptom of AIDS.
• Some viruses have been linked to certain
______ in humans and animals.
• These viruses disrupt the normal growth
and division of cells in a host, causing
abnormal growth and creating _______.
• Researchers have recently discovered some
particles that behave somewhat like viruses
and cause infectious diseases.
• Prions are composed of proteins but have no
nucleic acid to carry genetic information.
• Prions are thought to act by causing other
proteins to fold themselves incorrectly,
resulting in improper functioning.
• Prions are responsible for many animal
diseases, such as mad cow disease and its
human equivalent, Creutzfeldt-Jakob
disease.
• Viroids are composed of a single circular
strand of RNA with no protein coat.
• Viroids have been shown to cause
infectious diseases in several plants.
• The amount of viroid RNA is much
less than the amount found in viruses.
• The first virus to be identified was a
plant virus, called tobacco mosaic virus,
that causes disease in tobacco plants.
Tobacco mosaic virus
causes yellow spots
on tobacco leaves,
making them
unmarketable.
• Viruses cause as many as 1000 plant
diseases and are named according to
their host plant.
• Viruses can cause stunted growth
and yield losses in their host plants.
• Plant viruses require wounds or insect
bites to enter and infect a host, and do
not use surface recognition.
• They do not undergo lytic or
lysogenic phases.
• Not all viral plant diseases are fatal or
even harmful.
• Some mosaic viruses cause striking patterns
of color in the flowers of plants.
Rembrandt
tulips
• For replication, viruses need host cells;
therefore, scientists suggest that viruses
might have originated from their host cells.
• Some scientists suggest that viruses are
nucleic acids that break free from their
host cells while maintaining an ability to
replicate parasitically within the host cells.
Section Objectives 18.2
• Compare the types of prokaryotes.
• Explain the characteristics and adaptations
of bacteria.
• Evaluate the economic importance of
bacteria.
• Recall that prokaryotes are _________
organisms that do not have a nucleus or
membrane-bound organelles.
• They are classified in two kingdoms—
_________ and ________.
• Many _________ differences exist
between these two types of prokaryotes.
• Because they are so different, many
scientists propose that archaebacteria and
eubacteria arose from a _______ ancestor
several billion years ago.
• There are ____ types of archaebacteria that
live mainly in extreme habitats where there
is usually no free ______ available.
• One type of archaebacterium lives in
oxygen-free environments and produces
______ gas.
• These methane-producing archaebacteria live
in marshes, lake sediments, and the digestive
tracts of some ________, such as cows.
• They also are found at sewage disposal
plants, where they play a role in the
______ of sewage.
• A second type of archaebacterium lives only
in water with ____ concentrations of salt.
Dead Sea
• A third type lives in the hot, acidic
waters of ______ springs.
• This type of anaerobic
archaebacterium also thrives
near cracks deep in the ocean
floor, where it is the
_______ producer for a
unique animal community’s
food chain.
• ________, the other kingdom of prokaryotes,
includes those prokaryotes that live in places
more hospitable than archaebacteria inhabit
and that vary in nutritional needs.
• The ____________ eubacteria live almost
everywhere and use organic molecules as
their food source.
• Some bacterial heterotrophs are
______, obtaining their nutrients
from living organisms.
• Others are _______—organisms
that feed on dead organisms or
organic wastes.
• A second type of eubacterium is
the ___________ autotroph.
• These eubacteria live in places with
________ because they need light to
make the organic molecules that are
their food.
• ___________ are photosynthetic autotrophs.
• Most cyanobacteria
are _______ and
some are red or
yellow in color.
Cyanobacteria
• Cyanobacteria commonly live in ponds,
streams, and moist areas of land.
• They are
composed of
chains of
independent cells.
Cyanobacteria
• A third type of eubacterium is the
_________ autotroph.
• Unlike the photosynthetic bacteria, the
chemosynthetic bacteria do not obtain
the energy they need to make food
from _______.
• Instead, they break down and release the
energy of inorganic compounds containing
sulfur and nitrogen in the process called
____________.
• A _________ consists of a very small cell.
• Although tiny, a bacterial cell has all the
________ necessary to carry out its life
functions.
• Prokaryotic cells have ribosomes, but
their ribosomes are smaller than those
of eukaryotes.
• They also have genes that are located for the
most part in a single circular chromosome,
rather than in paired chromosomes.
Ribosome
Cytoplasm
Chromosome
Flagellum
Cell
Gelatinlike
Cell Wall Membrane
capsule
• A typical bacterium, such as _____________
would have some or all of the structures shown
in this diagram of a bacterial cell.
Capsule
Cell Wall
Chromosome
Plasma
membrane
Flagellum
Pilus
Plasmid
• A bacterial cell remains intact as long
as its cell ____ is intact.
• If the cell wall is damaged, ____ will
enter the cell by osmosis, causing the
cell to burst.
• Scientists used a bacterium’s need for
an intact cell wall to develop a weapon
against bacteria that cause ________.
• In 1928, Sir Alexander Fleming
accidentally discovered _______,
the first antibiotic—a substance that
destroys bacteria—used in humans.
• Later, biologists discovered that penicillin
can _______ with the ability of some
bacteria to make cell walls.
• When such bacteria grow in penicillin, holes
develop in their cell walls, water enters their
cells, and they rupture and die.
• One trait that helps categorize bacteria
is how they react to _____ stain.
• Gram staining is a technique that
distinguishes ___ groups of bacteria
because the stain reflects a basic
difference in the composition of
bacterial cell walls.
• After staining, Gram-_______ bacteria are
_____ and Gram-_______ bacteria are _____.
Gram-positive bacteria
Gram-negative bacteria
• Gram-positive bacteria are affected by different
antibiotics than those that affect Gram-negative
bacteria.
Gram-positive bacteria
Gram-negative bacteria
• Bacterial cell walls also give bacteria
different _____.
• The three most common shapes are spheres,
called _____; rods, called _____; and spirals,
called ________.
• In addition to having one of these shapes,
bacterial cells often grow in characteristic
_______ that provide another way of
categorizing them.
• _____–is a prefix that refers to a paired
arrangement of cell growth.
• The prefix _______–describes an
arrangement of cells that resemble grapes.
• _______–is a prefix that refers to an
arrangement of chains of cells.
• Bacteria reproduce ______ by a
process known as ______ _______.
• To reproduce in this way, a bacterium
first copies its chromosome. Then the
original chromosome and the copy
become attached to the cell’s plasma
membrane for a while.
• The cell grows ____, and eventually the two
chromosomes separate and move to opposite
ends of the cell.
• Then, a _______ forms between the
chromosomes. This partition separates the
cell into ___ similar cells.
• Because each new cell has either the
original or the copy of the chromosome,
the resulting cells are genetically identical.
• Under ideal conditions, some bacteria can
reproduce every ___ minutes, producing
enormous numbers of bacteria quickly.
• But bacteria don’t always have ideal growing
conditions. They run out of nutrients and water,
they poison themselves with their own
______, and predators eat them.
• In addition to binary fission, some bacteria
have a form of sexual reproduction called
______________.
• During conjugation (kahn juh GAY shun),
one bacterium ______ all or part of its
chromosome to another cell through or on
a bridge-like structure called a ____ that
connects the two cells.
• Conjugation results in a bacterium with a
___ genetic composition.
• This bacterium can then undergo binary
fission, producing more cells with the same
genetic makeup.
• Based on fossil evidence, some scientists
propose that ______ bacteria were probably
among the first photosynthetic organisms,
producing not only their own food but also
oxygen.
• As the concentration of oxygen increased
in Earth’s atmosphere, some bacteria
probably _______ over time to use oxygen
for respiration.
• Modern bacteria have diverse types of
______________.
• Many bacteria require ________ for
respiration. These bacteria are called ______
_________.
• There are other bacteria, called obligate
_________, that are killed by oxygen.
• There are still other bacteria that can live
either with or without oxygen, releasing the
energy in food _________ by cellular
respiration or anaerobically by _______.
• Some bacteria, when faced with unfavorable
environmental conditions, produce _______.
• An _________ is a tiny structure that contains
a bacterium’s ___ and a small amount of its
________, encased by a tough outer covering
that resists drying out, temperature extremes,
and harsh chemicals.
• As an ________, the bacterium rests
and does not _________.
• When environmental conditions improve,
the endospore ________, or produces a
cell that begins to grow and reproduce.
• __________ can survive a temperature of
100˚C, which is the boiling point of water.
• To kill endospores, items must be
________—heated under high pressure in
either a pressure cooker or an _______.
• Canned food must be sterilized and _______.
• This is because the endospores of the
bacterium called ________ ________
easily get into foods being canned.
• If the endospores of C. botulinum get
into improperly sterilized canned food,
they germinate.
• Bacteria grow in the ________ environment
of the can and produce a powerful deadly
poison, called a _____, as they grow.
• This deadly toxin saturates the food and, if
eaten, causes the disease called _______.
• A different bacterium, Bacillus _______,
lives in the soil.
• B. anthracis causes ______, a disease that
commonly infects cattle and sheep, but can
also infect humans.
• Most human anthrax infections are fairly
harmless and occur on the ___ as a result
of handling animals.
• The bacterial _________ can become
airborne, however, and if inhaled in large
amounts, can germinate in a person’s lungs,
causing an infection.
• This infection is more serious than a skin
infection and often _______.
• Disease-causing bacteria are few compared
with the number of harmless and beneficial
bacteria on Earth.
• Bacteria help to _______ fields, to recycle
nutrients on Earth, and to produce foods and
________.
• All organisms need ________ because the
element is a component of their proteins,
____, ____, and ___.
• Yet few organisms, including most plants,
can directly use _______ from the air.
• Several species of bacteria have enzymes that
convert __into ammonia (___) in a process
known as _______ _______.
• Other bacteria then convert the ammonia into
nitrite ____and nitrate ______which plants
can use.
• _______ are the only organisms that can
perform these chemical changes.
• Some nitrogenfixing bacteria live
________ within
the roots of some
trees and ______.
• Farmers grow legume crops after the
harvesting of crops such as _____,
which depletes the soil of nitrogen.
• ________ bacteria and also plants and algae,
which are at the bottom of the food chains, use
the nutrients in the food they make.
• This food is passed from one _________
to the next in food chains and webs.
• In the process of making food, many
autotrophs replenish the supply of
______ in the atmosphere.
• Some foods that you eat—mellow Swiss
cheese, crispy pickles, tangy yogurt—
would not _____ without bacteria.
• Specific bacteria are used to make different
foods, such as ______, cheeses, and
________.
• Bacteria also inhabit your _______ and
produce _______ and _______ that help
digest food.
• In addition to food, some bacteria produce
important ________ that destroy other types
of bacteria.
• ________, ________, bacitracin, and
neomycin are some of these antibiotics.
• Bacteria cause diseases in plants and
animals, causing crops and livestock
losses that impact humans indirectly.
• Bacteria also cause many human diseases.
• Disease-causing bacteria can enter
human bodies through openings,
such as the mouth.
• Bacterial diseases harm people in two ways.
• The growth of the bacteria can interfere
with the normal function of body _)___, or
it can release a _____ that directly attacks
the host.
Diseases Caused by Bacteria
Disease
Transmission Symptoms
Fever, sore throat,
Inhale or
Strep throat
ingest through swollen neck glands
(Streptococcus)
mouth
Inhale
Fatigue, fever, night
Tuberculosis
sweats, cough, weight
loss, chest pain
Puncture
Stiff jaw, muscle
Tetanus
wound
spasms, paralysis
Rash at site of bite,
Lyme disease
Bite of
infected tick chills, body aches,
joint swelling
Bacteria
Destruction of tooth
Dental
cavities (caries) in mouth
enamel, toothache
Sore throat, fever,
Inhale or
Diptheria
close contact heart or breathing
failure
Treatment
Antibiotic
Antibiotic
Open and clean wound,
antibiotic; give antitoxin
Antibiotic
Remove and fill the
destroyed area of tooth
Vaccination to
prevent, antibiotics
• In the past, bacterial illnesses had a
greater effect on human populations than
they do now.
• In the last 100 years, human life expectancy
has increased to about __ years.
• This increase is due to many factors,
including better public health systems,
improved ____ and sewage treatment,
better ________, and better medical care.
• These improvements, along with
_________, have reduced the death rates
from bacterial diseases to low levels.