Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Chromosomes and DNA replication Procaryotes: DNA is in the cytoplasm, circular Chromosome E. Coli Bacterium Bases on the Chromosomes Eucaryotes • DNA has 1000 X the base pairs as bacteria. • Located in the cell nucleus, on chromosomes • Folds into a space 1/1000th of its length by wrapping around the protein histone. – Eukaryotic Chromosome Structure Chromosome me DNA Coils Su Nucleosome: DNA wrapped around a histone DNA replication • DNA molecule separates • Each side acts as a template to make a complimentary new strand. • 1 molecule becomes 2 DNA replication cont’d • Enzymes “unzip” the molecule and it uncoils. • New N bases come in and bond to each side. • Polymerase joins them into a new molecule. • It also “proofreads” the new strands for errors. DNA Replication New Strand Original strand Nitrogen Bases Replication Fork Replication Fork DNA Polymerase Summary • One DNA strand becomes 2 identical strands, following the rules of base pairing. • Occurs at hundreds of sites along the chromosome at the same time.