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Disparities in Cancer September 22, 2008 Introduction • Despite notable advances in cancer prevention, screening, and treatment, a disproportionate number of the uninsured, minorities, and other medically underserved populations are still not benefiting from such important progress. • Underlying causes of cancer disparities are interrelated and complex. – Causes of cancer disparities can be linked to social, behavioral, and economic factors such as • • • • persistent inequalities in access to care, language barriers unhealthy environments racial discrimination Unequal progress can also increase disparities. At the same time that exposure to environmental tobacco smoke decreased, disparities have increased. Age-adjusted percent with detectable serum cotinine, age 4 and older 100 90 1988-94 1999-2000 93.9 87.8 83.4 80 72.0 70 60 52.0 50 44.1 40 30 20 10 0 Mexican American Black, non-Hispanic I 95% confidence interval * Nonsmokers defined by serum cotinine levels < 11 ng/mL. **Detectable serum cotinine levels: > .05 ng/mL and < 10 ng/mL. Notes: Age adjusted to the 2000 standard population. Data for other Hispanics, American Indians,/Alaska Natives, Asians/Pacific Islanders are unreliable. Source: National Health and Nutrition Examination Survey (NHANES), NCHS, CDC. White, non-Hispanic 3 Having insurance makes a difference. Uninsured persons are less likely than privately insured persons to receive timely cancer screenings. Uninsured Percent 83% Medicaid Private 88% 75% 68% 56% 48% 40% 38% 19% Received recommended Pap Test in Past colorectal cancer screening in Three Years, 2005 past 10 years, 2005 Women, 18-64 Adults, 50-64 Mammogram in Past Two Years, 2005 Women, 40-64 SOURCES: Ward, Elizabeth, et al. "Association of Insurance with Cancer Care Utilization and Outcomes." CA: A Cancer Journal for Clinicians 58.1 (2008): 9-31. 4 Health care providers can make a difference. Racial and ethnic minorities are less likely to be advised to quit smoking. Likelihood Hispanic 1.00 0.69 0.70 Screened for tobacco use Black 1.00 0.64 White 1.00 0.72 Advised to quit smoking 0.59 0.60 Used tobacco cessation treatments in the past year 5 SOURCES: Vilma 2008 Costs of care impact persons of lower socioeconomic status more. Small copays for mammography are more likely to deter lower education women from receiving mammograms. Percent Percent decrease in mammography due to copays 6 SOURCES: ayanian 2008 African Americans are more than 50% more likely than whites to be diagnosed with prostate cancer… Prostate Cancer Incidence Rates, 2004 Per 100,000 population White, Non-Hispanic 161.4 140.8 Incidence Hispanic 255.5 African American, Non-Hispanic 96.5 Asian and Pacific Islander American Indian/Alaska Native 68.2 7 Note: Data are age adjusted to the 2000 standard population. SOURCE: National Cancer Institute, Surveillence, Epidemiology, and End Results (SEER) Program; National Vital Statistics System--Mortality, NCHS, CDC. But African Americans are twice as likely than whites to die of prostate cancer. Prostate Cancer Death Rates, 2005 Per 100,000 population White, Non-Hispanic 22.6 18.5 Deaths Hispanic 53.3 African American, Non-Hispanic Asian and Pacific Islander American Indian/Alaska Native 10.4 17.6 8 Note: Data are age adjusted to the 2000 standard population. SOURCE: National Cancer Institute, Surveillence, Epidemiology, and End Results (SEER) Program; National Vital Statistics System--Mortality, NCHS, CDC. Incidence rates of breast cancer are highest in white women….. Breast Cancer Incidence Rates, 2005 Incidence Per 100,000 population White, Non-Hispanic 132.5 89.3 Hispanic 118.3 African American, Non-Hispanic 89 Asian and Pacific Islander American Indian/Alaska Native 69.8 9 Note: Data are age adjusted to the 2000 standard population. SOURCE: National Cancer Institute, Surveillence, Epidemiology, and End Results (SEER) Program; National Vital Statistics System--Mortality, NCHS, CDC. ….but death rates from breast cancer are highest in African American women. Breast Cancer Death Rates, 2005 Per 100,000 population White, Non-Hispanic 23.4 15 Deaths Hispanic 32.8 African American, Non-Hispanic Asian and Pacific Islander American Indian/Alaska Native 12.2 15.2 10 Note: Data are age adjusted to the 2000 standard population. SOURCE: National Cancer Institute, Surveillence, Epidemiology, and End Results (SEER) Program; National Vital Statistics System--Mortality, NCHS, CDC. Cancer mortality disparities vary greatly by region. For example, Blacks are more likely to die of breast cancer in Chicago than in New York City. New York City US Chicago 2.20 2.16 2.00 Mortality Rate Ratio 1.80 1.68 1.66 1.60 1.62 1.53 1.47 1.40 1.39 1.36 1.39 1.36 1.36 1.31 1.20 1.21 1.13 1.03 1.01 1.04 1.08 1.00 2000 2001 2002 2003 2004 2005 Year 11 Despite progress in fighting cancer, racial disparities can grow. The difference in black and white colorectal cancer death rates is almost 50 times larger than in 1978. Colorectal Cancer Death Rates Per 100,000 population 35 30 White Black 25 20 15 1973 1978 1983 1988 1993 1998 2003 12 Note: Data are age adjusted to the 2000 standard population. SOURCE: National Vital Statistics System--Mortality, NCHS, CDC. Having health insurance matters. Uninsured, publicly insured women are three times more likely to be diagnosed with a later stage of breast cancer than privately insured women Likelihood of being diagnosed with Stage III/IV breast cancer vs. Stage I breast cancer Insurance Status Private 1.0 2.9 Uninsured 2.7 Medicaid Medicare, 65+ 1.2 13 Note: Model adjusted for insurance type, race/ethnicity, age at diagnosis, income, proportion without high school degree, US census region, year of diagnosis, and facility type. SOURCE: Halpern et al, 2007 Race and ethnicity affects access to high quality treatment. Compared to whites, blacks are 50% less likely to receive appropriate treatment for breast cancer. American Indians are 70% less likely. Odds ratio of receiving inappropriate treatment Race/Ethnicity White, Non-Hispanic 1.0 1.3 Mexican 1.5 Black, Non-Hispanic Asian and Pacific Islander 0.9 1.7 American Indian/Alaska Native 14 SOURCE: Li et al. 2003. Differences in Breast Cancer Stage, Treatment, and Survival by Race and Ethnicity. Archives of Internal Medicine. 163:49-56. As new treatment technology is used, disparities may grow. Disparities in the receipt of sentinel node lymph biopsy by insurance status have grown as the technology has become more popular. Me dicaid Me dicare , 65+ Me dicare , 18-64 Uninsure d 2001 2003 Private % Receiving SLNB 70% 60% 50% 40% 30% 20% 1998 1999 2000 2002 2004 2005 15 Chen et al., Journal of Clinical Oncology 2008 Blacks are less likely than whites to use hospice services prior to their deaths from cancer. Percent 100 White 80 All P<0.001 60 46 44 40 Black 36 45 38 43 37 48 38 36 20 0 All cancers Lung Colorectal Breast Prostate 16 Virnig et al, Med Care 2002 Conclusion • Eliminating disparities in cancer screening, diagnosis, treatment, and mortality is an essential step toward improved health outcomes for all Americans with cancer. • Reducing cancer disparities can be achieved by instituting cost-effective public health programs that promote overall wellness and save lives. Thank You!