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Other Types of Genetic Crosses And their Punnett Squares Multiple Alleles Wild Type Red Eyes Mutant Apricot Eyes Example: Fruit fly eye colour Mutant White Eyes Mutant Honey Eyes Multiple Alleles More than 2 alleles for a gene. Dominance hierarchy. (One will dominate over others.) Show this in solution using the first letter of the gene name, then a superscript to reflect how dominant it is (1 is most dominant) Multiple Alleles Example: Fruit Fly eye colour (memorize this for test) – 4 alleles: Red, Apricot, Honey, White – Each allele shows some dominance, except White (E4): Red (E1): Dominant to all (E1E1, E1E2, E1E3, E1E4) Apricot (E2): Dominant over honey & white (E2E2, E2E3, E2E4) Honey (E3): Dominant over white (E3E3, E3E4) Codominance Example: Coat colour in horses Codominance Both alleles show up in hybrid. – Example: Some hairs are brown, some are white. There is NO dominant allele. Show this in Punnett Squares using the first letter of the gene word, and Superscripts – the first letter of the trait word. Codominance Example: A chestnut (red) horse and a white horse are crossed. All the offspring are roan (both red and white hairs). Let CR = Red Red horse: CRCR CW = White White horse: CWCW CR CR CW CRCW CRCW CW CRCW CRCW Incomplete Dominance Example: Colour of flowers in snapdragons Incomplete Dominance The alleles blend to form a different heterozygous phenotype. – Example: Having a red allele and a white allele will make the flower pink. We show this in a Punnett Square the same way as with Codominance. Incomplete Dominance Example: Purebred red snapdragons crossed with purebred white snapdragons produced pink snapdragons. Let CR = Red Red snapdragon: CRCR CW = White White snapdragon: CWCW CR CR CW CRCW CRCW CW CRCW CRCW ABO Blood Groups Four possible blood types: A, B, AB, and O. Both multiple alleles and codominance. – “A” allele (IA) codes for galactosamine on blood cell membrane (allows your body to recognize it as its own) – “B” allele (IB) codes for galactose – “O” allele (i) codes for neither Both IA and IB are dominant over i, but neither is dominant over the other – IAIB: both galactosamine and galactose are expressed Phenotypes: Genotypes A blood type: IAIA, IAi B blood type: IBIB, IBi O blood type: ii AB blood type: IAIB Donating & Receiving Blood Giving blood: – – – – O gives to everyone A can give to A and AB B can give to B and AB AB can give to AB Getting blood: – – – – AB can get blood from anyone A can get blood from A or O B can get blood from B or O O can only get blood from O