* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Hypohydrotic ectoderma dysplasia
Survey
Document related concepts
Pharmacogenomics wikipedia , lookup
X-inactivation wikipedia , lookup
Epigenetics of neurodegenerative diseases wikipedia , lookup
Genetic engineering wikipedia , lookup
History of genetic engineering wikipedia , lookup
Biology and consumer behaviour wikipedia , lookup
Behavioural genetics wikipedia , lookup
Human genetic variation wikipedia , lookup
Heritability of IQ wikipedia , lookup
Quantitative trait locus wikipedia , lookup
Population genetics wikipedia , lookup
Genetic testing wikipedia , lookup
Designer baby wikipedia , lookup
Medical genetics wikipedia , lookup
Microevolution wikipedia , lookup
Transcript
PRESENTED BY: GUADALUPE COMPEAN, DENTAL HYGIENE STUDENT DIANA MARTINEZ, DENTAL HYGIENE STUDENT LAMAR INSTITUTE OF TECHNOLOGY DENTAL HYGIENE PROGRAM Abnormal development of ectodermal structures Rare condition Occurs in an estimated one per 100,000 live births Linked to the X-chromosome Caused by the mutations of different genes before birth EDA (Ectodysplacin) Gene-Most common EDAR (Ectodysplacin Receptor) Gene-Least common Genetic Inherited from one or both parents Diagnosed at or shortly after birth Men more affected than women Considered X-linked if the mutated gene is located on the X chromosome Missing teeth Thin hair Dry, scaly skin Poor sweat glands High fevers Inadequate development of fingernails Facial Abnormalities oProminent supra orbital ridges oSunken cheeks and eyes oFrontal bossing oThick lips oLarger chin oSaddle nose Malformed teeth oPegged or conical shaped oWidely spaced Full medical/dental history Ask additional questions Family history Perform a thorough head & neck exam Oral exam Radiographs Refer for genetic testing Identifying subtle signs from a carrier such as slightly sparse and thin hair, coneshaped teeth, hypodontia, and partial sweat dysfunction Identify appropriate treatment Determine if dentures are needed Maintain the alveolar ridge for implant placement Achieve a fully functional dentition Aesthetics Dentures Dental implants Orthodontics Genetic research is developing fast and making advances in understanding the genes known for tooth development. In the future, tooth development and stem cell research could indicate the possibility to create new teeth artificially. Clauss, F., Chassaing, N., Smahi A., Vincent, M. C.,Calvas, P., Molla, M., Lesot, H., Alembik,Y., HadjRabia, S., Bodemer, C., Maniere,M. C., & Schmittbuhl, M. (2010). X-linked and autosomal recessive hypohidrotic ectodermal dysplasia: Genotypic-dental phenotypic findings. Clinical Genetics, 78, 257-266. Deshpande, S. N., & Kumar, V. (2010). Ectodermal dysplasia maxillary and mandibular alveolar reconstruction with dental rehabilitation: A case report and review of the literature. Indian Journal of Plastic Surgery, 43(1), 92-96. Jayantilal, P. R., Rajesh, S., Naveen Y. G., &Nandini, P. (2010). Treatment considerations for a patient with ectodermal dysplasia: A case report. Journal of International Oral Health, 2(4), 73-78. Lukes, S., & Sherry, J. S. (2010). Hypohidrotic Ectodermal Dysplasia. RDH, 31(1), 92-96. Retrieved from http://www.rdhmag.com Manuja, N., Passi, S., Pandit, I. K., & Singh, N. (2011). Management of a Case of Ectodermal Dysplasia: A Multidisciplinary Approach. Journal of Dentistry of Children, 78(2), 107-110. Shah, K. N. (2010, January 24). Ectodermal Dysplasia Treatment & Management. Medscape Reference: Drugs, Diseases, & Procedures. Retrieved from http://emedicine.medscape.com/article/1111595-overview The Swedish Information Center for Rare Diseases. (2011). Hypohidrotic ectodermal dysplasia. Retrieved from http://socialstyrelsen.se/raredisease/hypohidroticectodermal dysplasia#anchor_14