Download Translation: A homework problem asked: "Which one of the

Translation: A homework problem asked: "Which one of the
following steps in elongation is directly dependent on ATP or GTP
hydrolysis?" I picked polypeptide bond formation but the correct
answer is "attachment of charged tRNA to A site." I am confused,
doesn't attaching tRNA's just involve hydrogen bonding? Why is
peptide bond formation not the correct answer?
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(c) 2016 Brad Mehrtens <[email protected]>
URL: http://www.life.illinois.edu/mcb/150/private/faq/index.php?action=artikel&cat=10&id=1130&artlang=en
Translation: A homework problem asked: "Which one of the
following steps in elongation is directly dependent on ATP or GTP
hydrolysis?" I picked polypeptide bond formation but the correct
answer is "attachment of charged tRNA to A site." I am confused,
doesn't attaching tRNA's just involve hydrogen bonding? Why is
peptide bond formation not the correct answer?
Page 2/6
(c) 2016 Brad Mehrtens <[email protected]>
URL: http://www.life.illinois.edu/mcb/150/private/faq/index.php?action=artikel&cat=10&id=1130&artlang=en
Translation: A homework problem asked: "Which one of the
following steps in elongation is directly dependent on ATP or GTP
hydrolysis?" I picked polypeptide bond formation but the correct
answer is "attachment of charged tRNA to A site." I am confused,
doesn't attaching tRNA's just involve hydrogen bonding? Why is
peptide bond formation not the correct answer?
Page 3/6
(c) 2016 Brad Mehrtens <[email protected]>
URL: http://www.life.illinois.edu/mcb/150/private/faq/index.php?action=artikel&cat=10&id=1130&artlang=en
Translation: A homework problem asked: "Which one of the
following steps in elongation is directly dependent on ATP or GTP
hydrolysis?" I picked polypeptide bond formation but the correct
answer is "attachment of charged tRNA to A site." I am confused,
doesn't attaching tRNA's just involve hydrogen bonding? Why is
peptide bond formation not the correct answer?
Page 4/6
(c) 2016 Brad Mehrtens <[email protected]>
URL: http://www.life.illinois.edu/mcb/150/private/faq/index.php?action=artikel&cat=10&id=1130&artlang=en
Translation: A homework problem asked: "Which one of the
following steps in elongation is directly dependent on ATP or GTP
hydrolysis?" I picked polypeptide bond formation but the correct
answer is "attachment of charged tRNA to A site." I am confused,
doesn't attaching tRNA's just involve hydrogen bonding? Why is
peptide bond formation not the correct answer?
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(c) 2016 Brad Mehrtens <[email protected]>
URL: http://www.life.illinois.edu/mcb/150/private/faq/index.php?action=artikel&cat=10&id=1130&artlang=en
Translation: A homework problem asked: "Which one of the
following steps in elongation is directly dependent on ATP or GTP
hydrolysis?" I picked polypeptide bond formation but the correct
answer is "attachment of charged tRNA to A site." I am confused,
doesn't attaching tRNA's just involve hydrogen bonding? Why is
peptide bond formation not the correct answer?
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The tRNA is bound to an elongation factor (EF-Tu) which is bound
to GTP. If the anticodon matches the codon, then the ribosome deems it a
"good fit", the tRNA leans backwards and the ribosome with GTPase activity
hydrolyzes GTP and the tRNA changes conformation, dissociates from EF-Tu and
EF-Tu leaves. Peptide bond formation does not require a direct input of energy
because the bond between the amino acid and the tRNA in the P site is broken
which provides energy for the formation of a new bond. There is energy
"built in" since ATP was used to charge the tRNA and that energy is then
used when the bond between the tRNA and the amino acid is broken.
Unique solution ID: #2129
Author: Brad Mehrtens
Last update: 2013-08-25 18:07
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(c) 2016 Brad Mehrtens <[email protected]>
URL: http://www.life.illinois.edu/mcb/150/private/faq/index.php?action=artikel&cat=10&id=1130&artlang=en