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vitamin Chief metabolic function Effects of deficiency Vitamin -A (retinol) 1913 Essential for normal growth and development; for normal function of epithelial cells and normal development of teeth and bones. Prevents night blindness. Retarded growth. Reduced resistance to infection . Abnormal function of gastrointestinal, genitourinary, and respiratory tracts due to altered epithelial membranes . Interferes with production of “night purple”. Vitamin D (Cholecalciferol) 1925 Regulates absorption of calcium & phosphorus from the intestinal tract. Affords antiachitic activity. Interfers with utilisation of calcium and phosphorus in bone and teeth formation.Development of bone disease, rickets , caries. vitamin Chief metabolic function Effects of deficiency Vitamin- D (Cholecalciferol) 1925 Regulates absorption of calcium and phosphorus form the intestinal tract. Affords antiachitic activity. Interferes with utilizations of calcium and phosphorus in bone and teeth formation. Development of bone disease, rickets, Aries. Vitamin-E (Tocopherols) 1935 Protects tissues, cell membranes, and Vitamin A against peroxidation helps strengthen red blood cells Decreased red blood cell resistance to rupture. Vitamin- Chief metabolic function Effects of deficiency Vitamin-K (Phytomenadione) 1935 Essential for formation of normal amounts of prothrombin and blood coagulation. Diminished blood clotting time. increased incidence of hemorrhages. Water-Soluble Vitamins Vitamin-B1 (Thiamin) 1936 An important aid in carbohydrate metabolism. Needed for proper functioning of the digestive tract and nervous system. Loss if appetite. Impaired digestion of starches and sugars. Various nervous disorders, coordination. Vitamin- Chief metabolic function Effects of deficiency Vitamin-B2 (Riboflavin) 1935 Needed in formation of certain enzymes and in cellular oxidation. prevents inflammation of oral mucous membranes and the tongue. Impaired growth, lassitude and weakness. Causes challises or glossittis.May result in photophobias and cataracts. Vitamin-B6 (Pyridoxine) 1934 Acts, as do other B vitamins, to break down protein, carbohydrate, and fat. Acts as a catalyst in the formation of niacin form tryptophan. Increased irritability, convulsions, and peripheral neuritis. Anorexia, nausea and vomiting. Vitamin- Chief metabolic function Effects of deficiency Vitamin-B12 (Cyanocobalamin) 1948 Essential for development of red blood cells. Required for maintenance of skin, nerve tissues, bone and muscles. Results in pernicious anemia. Weakness, fati gue, sore and cracked lips Vitamin-C (Ascorbic Acid) 1919 Needed to form the cementing substance, collagen, in various tissues (skin, dentine, cartilage, ad bone matrix). Assists in wound healing; bone fractures. Lowered resistance to infections, susceptibility to dental cavities, pyorrhea, and bleeding gums. Delayed wound healing. Specific treatment for scurvy