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Origins of Life “The Scientific Story” Origin of the Universe and the Earth 14 billion years ago: • The “Big Bang” led to the formation of the stars of the “universe” • The Milky Way is one of many galaxies that make up the universe • The sun is the closest star to us 4.5 to 4.6 billion years ago: • Planets of our solar system were formed including our earth Conditions of the early earth: • very hot • barren rock • volcanoes • lightning • ultraviolet radiation • gases: • methane (CH4) • ammonia (NH3) • water vapor (H2O) • hydrogen (H2) • hydrogen sulfide (H2S) • hydrogen cyanide (HCN) Then what? • The earth’s temperature cooled over many years resulting in condensation and huge rains. • Oceans formed and covered the earth. These oceans were thought to be near boiling point. • Chemical Evolution took place, rearranging the atoms of the gases of the atmosphere into the building blocks of organic compounds. ORGANIC COMPOUND BUILDING BLOCK Protein Amino Acids (20 of them) Nucleic Acids (DNA / RNA) Nucleotides (ex: A T C G U) Carbohydrates Simple Sugars (example : Glucose) Lipids Fatty Acids & Glycerol Urey and Miller • In the 1950’s Harold Urey and Stanley Miller did an experiment to simulate the conditions of the primitive earth. • https://www.youtube.com/watch?v=NNijmxsKGbc Urey and Miller • What did they find? • Amino acids and Nucleotides had formed . • Conclusion? • Perhaps the building blocks of organic compounds could have formed on primitive earth (Chemical Evolution) The Jump… • It is thought that these compounds began to cluster together held by lipid molecules accumulating. These clusters were called Coacervates or Proteinoid Microspheres. • Scientists believe that these “abiotic” proteinoid microspheres made the jump to become the first living cell approximately 3.5 to 3.8 billion years ago. • Spontaneous Generation? Say what?? What did this first cell look like? • The first cell was likely: 1. Aquatic 2. Prokaryotic 3. Anaerobic 4. Heterotrophic - Oparin & Haldane’s Heterotroph Hypothesis • Aleksandr Oparin & John Haldane hypothesized that since the primordial oceans were full of organic compounds then the first life forms must have been consumers of these molecules (Heterotrophic) hence their Heterotrophic Hypothesis. Biological Evolution now begins • The following time line describes some of the big events: 2 billion years ago • photosynthetic prokaryotes evolve • releasing O2 into the atmosphere. • This brought about two major changes: • Aerobic environment • Formation of ozone (O3) • UV-rays 2O2 O + O + O + O O3 + O • Aerobic environment led to aerobic organisms evolving • With 18X more energy they could grow faster, reproduce faster and evolve faster. What Happened Next? • 1.5 billions years ago eukaryotes evolved • Large prokaryotic cell engulfs a smaller prokaryotic cell. • Resulted in the first eukaryotic cell (mitochondria and chloroplasts have their own DNA!!) Endosymbiotic Theory: • This theory suggests that eukaryotic cells arose from the symbiosis among several prokaryotic cells. • Some prokaryotic cells that had the ability to use oxygen gas to create energy rich ATP molecules became the MITOCHONDRIA (wow!) Endosymbiotic Theory Then what happened …. • What likely followed? 1. Aquatic multicellularity 2. Terrestrial Autotrophs 3. Terrestrial Heterotrophs Supplementary Material • Video on the Big Bang Theory (43 Minutes) https://www.youtube.com/watch?v=ofI03X9hAJI • Video on Endosymbiotic Theory (6 Minutes) https://www.youtube.com/watch?v=bBjD4A7R2xU