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Performance Modifiers 1 The Problem •After the realization that animals had a need for protein supplementation the livestock industry was still trying to find ways to increase efficiency and productivity. 2 The Solution • Practical methods of utilizing synthetic or manufactured compounds to enhance growth and efficiency were developed. • These Compounds: – Performance Modifiers 3 What is a Performance Modifier? • Somatotropins – Proteins that affect the utilization of energy in the body – Produced in the pituitary gland, located at the base of the brain. 4 Performance Modifiers • Examples – Injectables • Bovine Somatotropin (BST) • Porcine Somatotropin (PST) – Implants • Growth hormones and steriods 5 Bovine Somatotropin (BST) 6 BST and the Cow • Produced naturally in the pituitary gland, located at the base of the brain. • Causes energy derived from feed to be used for milk production rather than for weight gain. 7 Without BST? Energy From Food • Growth Milk _____________________________________ With BST Energy from Feed Growth Milk 8 Genetic Engineering & BST • The advancement in technology has allowed for the manufacture of “recombinant bovine somatotropin” (rBST) • The Food and Drug Administration approved rBST for use in November of 1993. 9 Administration of BST • Recommendation: – Injections should begin 9 weeks after the cow has calved – Repeat injection every 14 days throughout lactation – Discontinue use 2 weeks before the end of lactation 10 What cows should have BST? • The cow should be: – – – – In good body condition Gaining weight Well managed Fed a balanced ration with high quality forage 11 Which cows should NOT have BST? • Cows with: – – – – – – Poor health Poorly balanced rations Inadequate feed High somatic cell count Stress Breeding problems 12 Benefits of BST? • Increase milk production – 5 to 15 pounds/day 70 68 66 64 62 60 58 56 54 Normal +BST 13 Is it worth it? That is for the farmer to determine! 14 Porcine Somatotropin (PST) 15 What is PST? A protein produced in the pituitary gland Growth Regulator Production of PST decreases as a pig matures 16 What are the benefits of PST? Improves feed efficiency Improves gain Decreases fat deposition Causing less back fat Produces more muscle mass Leading to a bigger loin eye area 17 18 19 Making PST Successful Diet must consist of more protein and amino acids to support the increased growth rate. 20 Genetic Engineering & PST • PST is produced in the pituitary gland at the base of the brain. • Synthetically producing PST – Scientists have isolated the gene from the pig and inserted it into E. coli – E. coli then produces PST synthetically – The PST is then isolated and injected into the pig 21 Beef Cattle & Growth Implants 22 Growth Implants • Have been extensively used in beef production for over 30 years • Can be used in cattle from 45 days old and up – Use of implants in NOT recommended for replacement heifers or breeding bull calves 23 Benefits of Growth Implants • Suckling Calves – Improved weaning weights of 3-5% • Feeder calves – Improved feed efficiency and gain of 5-15% 24 Implant Use • Injected into the middle third of the back side of the ear • Outside the cartilage ring at the base of the ear 25 Nutrition Is Key! • Cattle must have adequate nutrition before the use of implants positively influences feed efficiency and gain 26 Problems with Growth Implants • Carcass Composition – Heavy carcass weight with large frame, exotic cattle – Poor yield grades in heifers with certain types of implants – Poor quality grades if implanting schedules are not managed appropriately 27 The key to successful results from implants depend on… Good Management 28