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How Did Life Begin? I thought we were done with all this chemistry stuff……. Molecular Building Blocks • Cells are composed of 4 types of macromolecules – I don’t have to tell you what they are • Today on earth these do not self-assemble from simpler molecules – Oxygen – Some life form would consume/modify them But on earth a long long time ago • Conditions were different than now • Atmosphere was hydrogen cyanide, CO2, CO, nitrogen, hydrogen sulfide, water vapor • If that was then and now is now….can you make organic molecules out of this stuff? • Stanley Miller and Harold Urey Experimental results are in • Miller and Urey’s device produced – Amino acids – Sugars – Nitrogenous bases But it’s a long way from here to there….. • Large organic molecules can organize themselves – Proteinoid microspheres form when polypeptide chains cool – These are hollow and surrounded by lipid • RNA is really important – – – – Probably was the first information molecule RNA can duplicate itself Rna can function as an enzyme (ribozyme) DNA likely evolved from RNA Origin of the Eukaryotes • Oxygen accumulates • Endosymbiotic theory – Mitochondria – Chloroplasts • Sex and multicellularity – Diversity…….diversity…….diversity Fossils • Know the process on page 539, fossil formation • Dating – Relative dating and index fossils – Radiometric dating • Half life concept – The geologic time scale – Plate tectonics Clade Dinosauria has survived • Macroevolution – Adaptation and extinction (look at graph on page 548) – Adaptive radiation and convergent evolution • Rate of evolution – Slow (= gradualism) – Fast in spurts (= punctuated equlibrium) • Coevolution matters to us – Insects and flowers