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Lecture 16 Web: pollev.com/ucibio Text: To: 37607 Type in: 169964 <your question> Energy generation overview Cellular compartments Where does Glycolysis occur? Where does TCA occur? Cytosol Mitochondria Cellular compartments http://www.sabiosciences.com/pathwaymagazine/minireview/mitchondrial_energy_metabolism.php Pyruvate Acetyl CoA What’s CoA? Pyruvate Acetyl CoA Pyruvate Acetyl CoA Pyruvate Acetyl CoA Regulation layer one: Within cell Regulation layer two: Signaling Sound familiar? Nicotinic acid NAD Riboflavin FAD Pantothenic acid CoA Biotin VITAMINS! Vitamins are metabolic cofactors Give rise to different “carriers” Need small amounts – cyclic! Energy generation overview The TCA TCA Regulation TCA Regulation TCA Regulation TCA Regulation TCA energy production TCA energy production TCA energy production Glucose energy production
