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Principles of Pharmacology Brenda Rowe, RN, MN, JD Pharmacokinetics Absorption Distribution Metabolism or biotransformation Excretion Pharmacodynamics (Effect of drug) Study of actions of the drug & changes that drugs undergo from absorption to excretion Receptor, Agonist, Antagonist propranolol (Inderal) beta adrenergic antagonist Pharmacotherapeutics Efficacy Adverse Effects Adverse Reaction Allergic response Drug Interaction Drug Toxicity Potentiation of Drug Effects Controlled Drugs Safety Precautions JACHO requirements Compliance of Client Behaviors Causes Patient Education Medication Errors Common errors Strategies to reduce Nursing Diagnoses Constipation Diarrhea Disturbed sleep patterns Urinary retention Interdisciplinary Management IOM Report Self-care Practices OTC Herbal Therapy Legal Issues Malpractice Advanced Practice Issues Impaired Healthcare Provider Removal of Drugs from Market Pharmaceutical Research Informed Consent Clinical Trials Ethical Considerations What is an orphan drug?