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How to search for Drug Monographs CPS (Compendium of Pharmaceuticals and Specialties with eTherapeutics) Atorvastatin has been the world's top-selling drug for several years. Statins are a class of drugs used to lower cholesterol levels. “I've heard that I should not consume grapefruit products while taking Lipitor (Atorvastatin). I love grapefruit juice but have given it up based on this information. Is this true? Will the occasional glass of grapefruit juice harm me?” Grapefruit products, such as grapefruit, grapefruit juice, or grapefruit supplements, can interact with some cholesterol-lowering statins and increase the level of medication in your blood. Lipitor (atorvastatin calcium) is one of these statins.