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Unit 4 Lesson 3 Your Brain on Drugs Objectives Discuss the effects of the various drugs of abuse on the brain Explain how drug use can lead to addiction Vocabulary Matching quiz! 1. 2. 3. 4. 5. Heroine Marijuana LSD Cocaine Steroids 6. 7. 8. 9. 10. Methamphetamines Tobacco Inhalants Alcohol Ecstasy Your Brain on Drugs Drugs and the Brain Addictive drugs enter the body through a number of routes, make their way into the bloodstream, and go straight to the brain where they exert their effects. Addictive drugs act on one part of the brain, the brain reward system. This part rewards us when we do the things we must do to survive eating and drinking. Cells in this part of the brain release chemicals that make us feel good (reward us) when we engage in these behaviors and teach us to repeat them. Drugs Impact on the Brain Drugs mimic the brain's natural chemicals. Instead of teaching us to repeat survival-oriented behaviors, drugs teach us to take more drugs. If use continues, drugs gradually change the brain and these changes can eventually lead to addiction. Such short-term effects as intoxication, impairment of judgment, and, occasionally, overdose are also the result of drugs' actions on the brain Heroin Heroin Heroin is a highly addictive opiate Brain cells can become dependent on this drug users need it in order to function in their daily routine. leaves the user in a fog for many hours afterwards Effects Depresses the body's ability to withstand infection It produces euphoria, drowsiness, respiratory depression, constricted pupils, and nausea It is the drug most often associated with the transmission of HIV/AIDS because most users inject the drug, often with used, contaminated needles As heroin leaves the brain and body, users experience withdrawal symptoms. They include watery eyes, runny nose, yawning, loss of appetite, tremors, panic, chills, sweating, nausea, muscle cramps, and insomnia. Blood pressure, pulse, respiration, and temperature all elevate Cocaine Cocaine Cocaine and crack come from the leaves of the coca plant, which grows primarily in South America. Cocaine is processed into a white powder which people snort or melt and inject. Crack is further processed into a substance that can be smoked Death occurs from cardiac arrest (the person's heart stops beating), or seizures followed by respiratory arrest (the person stops breathing). Effects Both forms of the drug trap a chemical called dopamine in the spaces between the brain's nerve cells in a part of the brain called the reward system. Dopamine stimulates and restimulates these nerve cells. The brain responds to the overabundance of dopamine by destroying some of it, making less of it, and shutting down the cells' receptors so they can no longer receive dopamine's messages. Inhalants Inhalants Inhalants are legal products abused by those who sniff or inhale them for the purpose of getting high. Inhalants fall into three categories: volatile solvents such as glue, gasoline, aerosols; anesthetics such as nitrous oxide; and nitrites such as amyl and butyl nitrite. Effects The fatty tissues protecting the nerve cells in the brain are destroyed by inhalant vapors. This slows down or even stops neural transmissions. Effects of inhalants include diminished ability to learn, remember, and solve problems. Ecstasy Ecstasy Ecstasy (MDMA) is a synthetic drug with both hallucinogenic and amphetamine-like properties. It is chemically similar to two other synthetic drugs, MDA and methamphetamine, which damage brain cells. Effects Users experience increases in heart rate and blood pressure, nausea, blurred vision, faintness, chills, sweating, and such psychological problems as confusion, depression, sleep problems, craving, severe anxiety, paranoia, and psychotic episodes. LSD LSD LSD (lysergic acid diethylamide) is one of the major hallucinogenic drugs and one of the most potent mood-changing chemicals. Effects Results can be unpredictable Physical effects include higher body temperature, increased heart rate and blood pressure. The user may experience delusions and visual hallucinations which can cause panic. Methamphetamine Methamphetamine Methamphetamine is an addictive stimulant that strongly activates certain systems in the brain. Ice is methamphetamine that has been crystallized so it can be smoked. Ice is a stimulant. It stimulates the central nervous system, resulting in increased activity and alertness. Effects Physical effects of ice include: heart palpitations, blurred vision, extended wakefulness, and damage to the brain, lungs, and liver. Methamphetamine can interfere with vision, judgment, coordination, and reflexes, which may lead to automobile and other machinery accidents. Behavioral effects include violence, hallucinations, depression, and psychosis. Marijuana Marijuana Marijuana contains chemicals that act on the marijuana receptor in the brain Scientists have recently identified the natural chemical, anandamide, designed to fit the marijuana receptor Can have a dangerous effects on judgment and reaction time-motor vehicle accidents Effects The parts of the brain that control emotions, memory, and judgment are affected by marijuana Smoking it can not only weaken short-term memory, but can block information from making it into longterm memory It has also been shown to weaken problem solving ability Alcohol Alcohol Alcohol is a drug. It impairs judgment and leads to memory lapses. It can lead to blackouts. It distorts vision, shortens coordination Can cause damage to brain, kidneys, and liver Effects Drunk drivers kill about 23,000 Americans a year. Very large amounts of alcohol can cause death from overdose by reducing the number of messages the brain sends to the chest muscles that regulate breathing. Can lead to physical dependence. Causes many kinds of cancer and can permanently damage the brain Alcohol can destroy the part of the brain where short-term memory occurs, making it impossible to learn anything new Temperance movement-lead by many religious movements and women 1852 Elizabeth Cady Stanton and Susan Anthony found the New York State Women's Temperance Society 1874 Women's Christian Temperance Union founded October 1919, 18th Amendment to the U.S. Constitution, which prohibited the manufacture, transportation, and sale of alcoholic beverages in the United States. The complete ban on alcohol was put into effect by the Volstead Act President Wilson vetoed the act, but Congress overrode the veto and the United States became officially dry in January 1920. On December 5, 1933, the 21st Amendment to the U.S. Constitution was ratified, and the "noble experiment" was dismantled. Steroids Steroids Anabolic steroids are used to improve athletic performance and gain muscle bulk. Steroids are derivatives of the male hormone, testosterone. Promote the growth of skeletal muscle and increase lean body mass Athletes and non-athletes use steroids illegally to enhance performance and to improve physical appearance Effects Steroids cause moodiness, even aggressiveness Can permanently impair learning and memory abilities Tobacco Tobacco Tobacco is a dangerous drug, and it works by putting nicotine, into the body Nicotine affects the brain quickly, like other inhalants, producing feelings of pleasure, like cocaine, and is highly addictive, like heroin Tobacco is a plant grown in the United States that is harvested and processed into cigarettes, cigars, pipe tobacco, chewing tobacco, and snuff Nicotine itself is toxic–high doses can kill, but do so rarely. Its most destructive property is its ability to addict users rapidly Effects Smokers expose their brains and bodies to hundreds of toxic chemicals contained in tobacco and tobacco smoke Cancers of the mouth, head, and neck , and cancers involving most of the vital organs Smoking also causes heart disease, emphysema, and other lung diseases Cigarette smoke can also harm nonsmokers. Children whose parents smoke suffer higher rates of bronchitis and other lung infections, and nonsmoking spouses of smokers have higher rates of lung cancer than those whose spouses do not smoke Every year, tobacco kills more than 400,000 Americans. This is more deaths than all Americans killed in World War I, World War II, and the Korean and Vietnam wars combined Upcoming Events Unit 5 Lesson 1 Sensation. Unit 5 Portfolio has been skipped, still read the lesson, but no portfolio is due! Unit 6 Portfolio has been modified! Temporary zeros in for Unit 3! Make sure you are not falling too far behind, remember January 22nd, is the last day of the semester, unfinished work turns into a zero!!! Thank You!! Have a Good Weekend!