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Digestive Process and Enzymes Review • What is the difference between physical digestion and chemical digestion? • What is an enzyme? • Why are enzymes specific to one substrate? • Chemical digestion involves the hydrolysis of macromolecules in food • Enzymes are required - why? • Water is also required - why? • Each digestive enzyme has a specific substrate (examples?) • Each area of the digestive tract has a specific pH range; this is the optimal pH for enzymes that work there • pH in the mouth is 7; in the stomach is 2; in the small intestine is 7 to 8 • HCl in gastric juice causes the low pH of the stomach • required for the conversion of pepsinogen into pepsin What other functions does the acidity of the stomach have? • Digestive enzymes are produced by glands - where are these located? – mouth - salivary glands – stomach - gastric glands – pancreas – most cells of the pancreas – small intestine (intestinal glands in walls) Name the enzymes produced by: • Mouth – Salivary amylase • Stomach – pepsin • Pancreas – Pancreatic amylase, lipase, trypsin, nuclease • Small intestine – Maltase, peptidase Products • What are the final products of digestion? • glucose and other monosacharides, amino acids, fatty acids, glycerol, nucleic acids Absorption • How do nutrients get into the blood from the small intestine? – Absorbed through the cell membranes, by facilitated transport • Where does the blood go first, as it leaves the digestive tract? – Liver, via hepatic portal vein • How do nutrients get into cells where they are needed? – Facilitated transport through cell membranes Which structure releases an enzyme that would catalyze the production of the above molecules? a)Liver b)Salivary glands c)Pancreas d)Stomach