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The Digestive System pH lecture Functions of Digestive System Ingestion – active, conscious process of taking materials into mouth Mechanical Processing – crushing process that increases the surface area of the food, exposing it to more enzymatic activity (occurs in mouth and stomach) Digestion – break down of food into small fragments suitable for absorption Functions of Digestive System (Continued) Secretion – release of water, acids, enzymes and salts by epithelium of digestive tract Absorption – movement of ions, vitamins, and water across digestive epithelium into interstitial fluid of digestive tract Excretion – removal of waste from body fluids Digestive Pathway Oral cavity (teeth and tongue) Pharynx Esophagus Stomach Small Intestine – Duodenum, Jejunum, Ileum Large Intestine – Cecum or (ascending Colon), Colon or (Transverse Colon), Rectum or (Descending Colon) Digestive Pathway CONT….. Don’t forget to label the 3 parts of each type of intestine, the pancreas and the appendix Histology of Digestive Tract Two major types of tissue that constantly produce a lubricating liquid, allowing all components of digestive tract to slide without friction Visceral peritoneum – covers organs Parietal peritoneum – lines inner surfaces of body wall Oral Cavity Also referred to as the buccal cavity Functions to: – Perform sensory analysis of material before swallowing – Mechanically process material with teeth, tongue, and palatal surfaces – Lubricate material by mixing it with mucus and saliva – Perform limited digestion of carbohydrates and lipids Anatomy of Oral Cavity (Continued) The tongue functions to: Mechanically process food Manipulate food to assist in chewing Sensory analysis through touch, temp, and taste Secretion substances including the enzyme lingual lipase (which initiates lipid digestion) Saliva and Salivary Glands 3 pairs of salivary glands: – Parotid salivary gland – produce saliva that has high concentration of salivary amylase (begins to break down starches, though no absorption occurs in oral cavity) • 25% of Saliva – Sublingual salivary gland – produce saliva that acts as buffer and lubricant • 5% – Submandibular salivary gland – produce saliva rich in buffer, libricating proteins called mucins, and salivary amylase • 70% Bad Breath Clinically termed Halitosis Typically caused by breakdown of epithelial cells, blood cells, and bacteria combined with saliva on tongue Low Salivary flow – dehydration and morning breath due to breathing through mouth during sleep Garlic and Onion Breath – compounds taken in blood to lungs Teeth Perform mastication (chewing) Mastication breaks down tough connective tissues in meat and plant fibers and helps to saturate food with saliva Pharynx and Epiglottis Pharynx: common passageway for food, liquid, and air Epiglottis: prevents food from going into the trachea and instead directs it to the esophagus Esophagus A hollow muscle tube approximately 25 cm long and 2 cm in diameter Empties into the stomach through the cardiac sphincter, which prevents backflow from the stomach into the esophagus Peristalsis= muscle movement of the esophagus. Food at this area is called bolus Stomach Performs 4 major functions: – Stores ingested food – Mechanically breaks down ingested food – Chemically breaks down ingested food Ingested substances combine with digestive juices of stomach to form acidic soupy substance called chyme Anatomy of Stomach Shaped like a J Lesser curvature (1st part) Greater curvature (2nd part) Can be divided into four regions: – – – – Cardia Fundus Body Pylorus • Pyloric sphincter regulates the release of chyme into the small intestine Stomach’s Volume Volume of stomach increases while you eat and decreases as it releases chyme When full it can contain between 11.5 liters of material Mechanical & Chemical Digestion Digestive System Functions Digestion—breaking food down both physically & chemically Food breakdown as mechanical digestion Mixing food in the mouth by tongue & teeth, churning food in stomach & segmentation in small intestine Mechanical digestion prepares food for further degradation by enzymes Digestive System Functions Digestion—breaking food down both physically & chemically Food breakdown as chemical digestion Enzymes break down food molecules into their building blocks Each major food group uses different enzymes Carbohydrates are broken to simple sugars Mouth & small intestines Proteins are broken to amino acids Stomach & small intestines Fats are broken to fatty acids & alcohols Small intestines Responsible for 90% of nutrient absorption (most of rest occurs in large intestine) Averages 6 m (19.7 ft) in length Averages diameter of 2.54.0 cm Duodenum – “mixing bowl” – combines chyme with digestive secretions from pancreas and liver Jejunum – bulk of chemical digestion and nutrient absorption occurs here Ileum – the longest segment which ends in ileocecal valve (separating ileum from cecum of large intestine) The Small Intestine Histology of Small Intestine Plicae circulares are folds that line the small intestine, greatly increasing surface area for absorption Plicae are lined by tiny fingerlike projections called intestinal villi, which are covered by simple columnar epithelium Pancreas Lies posterior to the stomach and is bound posteriorly to abdominal cavity Produces 1000 ml of digestive enzymes/day (pancreatic juice) and delivers them to the duodenum through pancreatic duct When chyme enters the small intestine, it triggers the duodenum to release the hormone secretin, which in turn stimulates the pancreas to release these enzymes Liver The largest visceral organ, weighing about 1.5 kg Primary function is to regulate the composition of circulating blood Blood from absorptive surfaces of digestive tract enters liver Liver cells extract nutrients or toxins from blood and then allows filtered blood to reenter systemic circulation It stores excess nutrients, and releases these to correct nutrient deficiencies Gallbladder Stores and concentrate bile immediately before it is released in the the small intestine It only releases bile when stimulated by the intestinal hormone cholecytstokinin CCK, which is released when chyme enters the duodenum The Large Intestine Begins where it meets the Ilium and ends at the anus Major functions: Reabsorption of water and the compaction of intenstinal contents into feces Absorption of vitamins liberated by bacterial action The storage of fecal material prior to defecation More About the Large Intestine Approx. 1.5 m long 7.5 cm wide Divided into three parts: Cecum Colon (ascending, transverse and descending) Rectum Regions of Colon The Rectum Expandable Temporarily stores feces, as movement of feces into rectum triggers urge to defecate Anal canal is last portion of rectum Internal anal sphincter – involuntary (smooth) External anal sphincter – voluntary (skeletal) Constipation Usually results due to an infrequent urge to defecate Infrequent bowel movements (fewer than 3 per week) Difficulty in at least 25% of the movement Feeling of incomplete evacuation Type 1 and 2 qualify as constipated Potential Causes – – – – Incomplete chewing of food Insufficient fiber in diet Dehydration Quitting smoking (nicotine is a laxative) THE END Vestigial Structures Click on the picture to watch the movie!