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Physiology of the digestive system • There are Four Stages of Food Processing: • Ingestion—the taking in of food • Digestion—the breakdown of food • Absorption—the taking up of nutrients • Elimination—the removal of waste materials from the body The digestive system  Digestion is when food undergoes physical and chemical changes that transforms complex food molecules into simple nutrients allowing us to use the energy  Mechanical digestion physically breaks up food into smaller particles increasing the surface area facilitating chemical digestion (breakdown by chemicals). The Mouth ( oral cavity)  Contains :  teeth -mechanically break down food.  a tongue- tastes and manipulates food.  the uvula, the flap hanging down at the back of the throat (closes the nasal cavity when swallowing, gag reflex)  salivary glands that produce saliva that lubricate food and start digestion teeth tongue uvula The Pharynx  Area at the back of the throat.  It is the area where the air and food pass.  A flap called the epiglottis closes the airway when food is swallowed. pharynx epiglottis The Esophagus  Muscular tube  Connects pharynx to stomach.  Moves food by means of peristalsis (sequential contractions of muscles e.g. in the esophagus) The Stomach  Muscular bag  Grinds food and mixes it with hydrochloric acid and enzymes into what is called chyme (partially digested food with the consistency of cottage cheese).  The stomach is lined with a mucus membrane that resists the acid.  Two sphincters (muscular rings) control entrance and exit of food. Small Intestine  7 m long  It is where digestion and absorption of nutrients and vitamins •Walls are covered in folds which are covered with villi (fingerlike projections) which are intern covered with microvilli (hairlike structures on the villi) •This increases the surface area folds VILLI Large Intestines  Also called the colon.  1.5m long (6.5 cm across)  absorbs most of the water  Has a smooth mucus lining to facilitate the passage of waste.  Rectum- storage of waste  Anus- opening for elimination Digestive Glands  A gland is an organ or group of cells that produces secretions.  Secretions are chemical substances (hormones) or liquids (sweat, mothers milk) that have different functions in the body.  The Salivary glands:  found in the mouth.  secret about1-1.5L of saliva daily.  The saliva lubricates the “bolus” (mashed food) and is involved in the breaking down of carbohydrates  The liver:  It produces bile (breaks down fats) daily  Some of the bile is stored in the gall bladder.  The pancreas:  This gland secretes pancreatic juices (digestive juices)  Also secretes insulin ( a hormone for the metabolism of sugar)  Gastric glands:  found over the entire internal surface of the stomach  Secretes gastric juices that digest only protein (contains HCl and pepsin) The Digestive tract Pharynx Epiglottis Uvula Oral Cavity Tongue Salivary Glands Esophagus Liver Gall Bladder Duodenum Transverse Colon Ascending Colon Cecum Appendix Anus Stomach Pancreas Jejunum Descending Colon Rectum