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Figure 23.1 Alimentary canal and related accessory digestive organs. Mouth (oral cavity) Tongue Esophagus Liver Gallbladder Duodenum Jejunum Small intestine Ileum Anus Copyright © 2009 Pearson Education, Inc. Parotid gland Sublingual gland Salivary Submandibular glands gland Pharynx Stomach Pancreas (Spleen) Transverse colon Descending colon Ascending colon Cecum Sigmoid colon Rectum Appendix Anal canal Large intestine Figure 23.1 Alimentary canal and related accessory digestive organs. Copyright © 2009 Pearson Education, Inc. Figure 14.1 Organs and accessory organs of the digestive system and their functions. Copyright © 2009 Pearson Education, Inc. Figure 23.6 Basic structure of the alimentary canal. Glands in submucosa Mucosa • Epithelium • Lamina propria • Muscularis mucosae Submucosa Muscularis externa Nerve Artery Vein Mesentery Gland in mucosa Lymphatic Duct of gland outside vessel mucosa Copyright © 2010 Pearson Education, Inc. • Longitudinal muscle • Circular muscle Serosa • Epithelium • Connective tissue Lumen Mucosa-associated lymphoid tissue Figure 23.7b Anatomy of the oral cavity (mouth). Gingivae (gums) Hard palate Soft palate Uvula Palatine tonsil Tongue Sublingual fold with openings of sublingual ducts Copyright © 2010 Pearson Education, Inc. Opening of submandibular duct Figure 23.9a The salivary glands. Ducts of sublingual gland Tongue Teeth Parotid gland Parotid duct Sublingual gland (a) Copyright © 2010 Pearson Education, Inc. Body of mandible (cut) Submandibular duct Submandibular gland Figure 14.6 Swallowing. Copyright © 2009 Pearson Education, Inc. Figure 14.3 Motility of the gastrointestinal tract. Copyright © 2009 Pearson Education, Inc. Esophagus • Mucosal epithelium is stratified squamous Stomach • Mucosal epithelium is simple columnar • Liquified food in the intestinal tract, first produced in the stomach is chyme. • Contents of the intestinal tract in the fetus is meconium. Figure 23.14a Anatomy of the stomach. Esophagus Muscularis externa • Longitudinal layer • Circular layer • Oblique layer Lesser curvature Serosa Body Lumen Rugae of mucosa Greater curvature Duodenum (a) Copyright © 2010 Pearson Education, Inc. Pyloric sphincter (valve) at pylorus Figure 23.16 Photographs of a gastric ulcer lesion and of the bacteria that most commonly cause it. Bacteria Mucosa layer of stomach (a) A gastric ulcer lesion Copyright © 2010 Pearson Education, Inc. (b) H. pylori bacteria Microscopic Anatomy of the Stomach Figure 22.15 Small Intestine • Three subdivisions: duodenum, jejunum, and ileum • The bile duct and main pancreatic duct join the duodenum at the hepatopancreatic ampulla Figure 14.9e The wall of the small intestine. Copyright © 2009 Pearson Education, Inc. Figure 14.9c–d The wall of the small intestine. Copyright © 2009 Pearson Education, Inc. Figure 14.10 Locations and digestive functions of the liver, gallbladder, and pancreas. Copyright © 2009 Pearson Education, Inc. Figure 14.10 Locations and digestive functions of the liver, gallbladder, and pancreas. 4 1 2 6 5 7 3 Copyright © 2009 Pearson Education, Inc. 8 Figure 23.21 The duodenum of the small intestine, and related organs. hepatic ducts of liver Bile duct Pancreas Jejunum Gallbladder Main pancreatic duct Hepatopancreatic ampulla and sphincter Copyright © 2010 Pearson Education, Inc. Duodenum Pancreas • Exocrine function – Secretes pancreatic juice which contains enzymes which break down all categories of foods – Secretes HCO3– which neutralizes acidic chyme, and provides optimal environment for pancreatic enzymes • Enzymes are released in inactive form and activated in the duodenum Figure 23.26a Structure of the enzyme-producing tissue of the pancreas. Small duct Acinar cells Basement membrane Zymogen granules Rough endoplasmic reticulum (a) Copyright © 2010 Pearson Education, Inc. Liver • The largest gland in the body • Has four lobes • Hepatic artery- brings oxygen rich blood to the liver • Hepatic portal vein- brings nutrient rich blood from the digestive organs to the liver • Both of these empty into the sinusoids of the liver Figure 14.11 The hepatic portal system. Copyright © 2009 Pearson Education, Inc. Figure 23.25a-b Microscopic anatomy of the liver. (a) Lobule Copyright © 2010 Pearson Education, Inc. (b) Central vein Connective tissue septum Liver: Microscopic Anatomy • Liver sinusoids – enlarged, leaky capillaries • Kupffer cells – hepatic macrophages found in liver sinusoids • Hepatocytes’ functions include: – – – – – – Production of bile Processing bloodborne nutrients Storage of fat-soluble vitamins Detoxification Protein synthesis Synthesis of cholesterol • Secreted bile flows between hepatocytes toward the bile ducts Figure 23.25c Microscopic anatomy of the liver. Interlobular veins (to hepatic vein) Central vein Sinusoids Bile canaliculi Plates of hepatocytes Bile duct (receives bile from bile canaliculi) Hepatic macrophages in sinusoid walls Portal vein (c) Copyright © 2010 Pearson Education, Inc. Bile duct Portal venule Arteriole Portal triad Figure 14.19 Gallstones Copyright © 2009 Pearson Education, Inc. Large Intestine • Subdivided into the cecum, appendix, colon, rectum, and anal canal – Cecum and appendix have digestive function in herbivores • Has three bands of longitudinal smooth muscle in its muscularis Figure 23.30d Mesenteries of the abdominal digestive organs. Liver Lesser omentum Pancreas Stomach Duodenum Transverse colon Mesentery Greater omentum Jejunum Ileum Visceral peritoneum Parietal peritoneum (d) Copyright © 2010 Pearson Education, Inc. Urinary bladder Rectum Figure 23.30a Mesenteries of the abdominal digestive organs. Liver Gallbladder Spleen Stomach Greater omentum Small intestine Cecum (a) Copyright © 2010 Pearson Education, Inc. Figure 23.30b Mesenteries of the abdominal digestive organs. Liver Gallbladder Lesser omentum Stomach Duodenum Transverse colon Small intestine Cecum (b) Copyright © 2010 Pearson Education, Inc. Figure 23.30c Mesenteries of the abdominal digestive organs. Transverse colon Descending colon Jejunum Mesentery Sigmoid colon Ileum (c) Copyright © 2010 Pearson Education, Inc. Tooth Structure Copyright © 2009 Pearson Education, Inc. Figure 22.11 Tooth Structure 1 • Two main regions – crown and the root • Crown – exposed part of the tooth above the gingiva (gum) – Covered with enamal, the hardest substance in the body, which is composed of calcium and phosphate salts • Root – portion of the tooth embedded in the jawbone – Covered with cementum, which is also calcified Copyright © 2009 Pearson Education, Inc. Tooth Structure 2 • Periodontal ligament – Anchors the tooth in the jaw • Dentin – bonelike material beneath the enamel cap that forms the bulk of the tooth • Pulp cavity –center of tooth, containing connective tissue, blood vessels, and nerves • Root canal – extension of the pulp cavity out of the root Copyright © 2009 Pearson Education, Inc. • Teeth are classified according to their shape and function – Incisors: chisel-shaped teeth adapted for cutting or nipping – Canines: conical or fanglike teeth that tear or pierce – Premolars (bicuspids) & molars (tricuspids): have broad crowns with rounded tips and are best suited for grinding or crushing Copyright © 2009 Pearson Education, Inc. Figure 23.10a Human dentition. (DON’T NEED TO KNOW AGE OF APPEARRANCE OF TEETH) Incisors Central (6–8 mo) Lateral (8–10 mo) Canine (eyetooth) (16–20 mo) Molars First molar (10–15 mo) Second molar (about 2 yr) (a) Copyright © 2010 Pearson Education, Inc. Deciduous (milk) teeth Incisors Central (7 yr) Lateral (8 yr) Canine (eyetooth) (11 yr) Premolars (bicuspids) First premolar (11 yr) Second premolar (12–13 yr) Molars First molar (6–7 yr) Second molar (12–13 yr) Third molar (wisdom tooth) (17–25 yr) Permanent teeth