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Diet, Lifestyle & Staying Well Paul Reilly, ND, L.Ac., FABNO Seattle Cancer Treatment & Wellness Center National Director of Naturopathic Medicine - CTCA 1 2 Risk Factors for Cancer • • • • • Tobacco 30% Diet 30% Infection 5% Alcohol 3% Pollution 2% • • • • • Reproductive Factor 3% Family history 5% Sedentary Lifestyle 5% Occupational 5% Other 12% (Harvard Center for Ca Prevention) 3 Nature or nurture? • Swedish twins study • 44,788 pairs of twins • 10,803 cases of cancer • genes explained risk as follows –prostate cancer - 42% of risk –colon cancer - 35% of risk –breast cancer - 27% of risk –lung - 26% of risk –most other cancers - <25% of risk 4 “Change the environment” Food Supplements Exercise Clean Environment 5 Just know this... • Change the internal environment that allows cancer to grow and you have changed everything related to risk and even recovery if cancer already exists 6 Development of Cancer 7 “Let your food be your medicine and your medicine be your food” Hippocrates 8 How Foods Fight Cancer • Antioxidants can slow damage to DNA • Phytochemicals change gene expression • Vitamins help repair DNA • EFA’s regulate growth signals & inflam. • Fiber enhances cell-cell communication • Regulation of hormones • Enhancement of detoxification 9 Paleolithic Nutrition •Avg daily intake – 3000 calories – 251 grams protein – 71.3 grams fat – 333.6 grams complex carbs – 45.7 grams fiber 10 Nat’l Health & Nutrition Survey •Less than 10% of Americans consume 5 serving of fruits and vegetables daily • 40% had no fruit or juice • 50% had no garden vegetables • 70% had no fruit or veg. High in vitamin C • 80% had no fruit or veg. high in carotenoids 11 Top 3 American Vegetables •#1: French fries –Account for 25% of all “vegetables” consumed in US •#2: Iceberg Lettuce –(90% water) •#3: Tomato –catsup & salsa 12 So What do I eat? American Heart Assoc ATKINS Macrobiotic 13 So What do I eat? American Heart Assoc ATKINS The “Real Food” Diet Macrobiotic 14 Dietary Guidelines •EAT LOTS: –Vegetables: (tomato, crucifers, garlic/onions) –Fruit: (apples, citrus, berries, apricots etc) –Lean protein (seafood, whey, soy, non-fat yogurt, beans) –Complex carbs: (whole grains, beans, fiber) –Good fats (olive oil, nuts, flax meal) –Herbs: (shitake mushrooms, ginger, curry etc) –Other: fermented foods, green tea, pure water. 15 Dietary Guidelines •Whole unrefined, unprocessed foods •Half plate should be vegetables •Eat a “rainbow” of color daily •Chew food well •1 oz water for every 2 pounds wt •Organic when available 16 Dietary Guidelines •Minimize or Avoid: – Commercial beef, pork & poultry – alcohol – full fat dairy products – sugar and desserts – microwaved foods 17 Dietary Guidelines •“Just Say No”: –High fructose corn syrup –Margarine, trans fats, partially hydrogenated fats, deep fried foods –Processed meats, nitrates, smoked meats (esp charred) –“fake foods”, colorings , additives 18 Superfoods • • • • • • • Spirulina Sprouts Bee Pollen Whey protein Pomegranite Green tea Garlic & onion • • • • • • Beets Apples Blueberries Turmeric & Ginger Coconut Mushrooms 19 FISH OILS • Increased intake of fish oils is associated with reduced risk of cancer incidence and metastasis –Breast( Nutr. Ca. 1989;12:61) –Colon (Gastroenterology 1993;105:1317) –Prostate (Antican. Res. 1996;16:815) • Reduces inflammation & heart disease 20 Alcohol and Cancer Type of Cancer # studies % increase per drink Tobacco synergy Breast 60 10% Colon 45 5% Rectal 45 5% Liver 25 20% Oral >50 30% Yes Esophagus 30 30% Yes 21 Sugar & Cancer • High sugar diets are associated with increased risk of several cancers. –Breast - Lancet 1996;347:1351 • Br. Ca. Res. & Tx. 1997;42:243 • Nutr. Ca. 1982 ;1:27 –Colorectal - Int’l J. Ca 1997;72:56 • Int’l J. Ca. 1998;75:40 • Nutr. Ca. 1987;10:181 • Ca. Epid. Biomarker Prev. 1997;6:67 22 Rachel Carson - Silent Spring • “For the first time in the history of the world, every human being is now subjected to contact with dangerous chemicals. ...The synthetic pesticides have been so thoroughly distributed throughout the animate and inanimate world that they occur virtually everywhere” 23 Pesticides 24 Toxins in Human Fat • 5 toxins found in 100% of samples. – dioxins, styrene, xylene, ethylphenol, 1,4 dichlorobenzene. • 9 toxins found in 91-98% of samples. – benzene, toluene, DDE, three dioxins, furans, ethyl benzene and chlorobenzene • PCBs found in 83% and lindane in 87% • 20 toxic compounds found in 76% of all samples 25 Pollution Effects • Cancer, leukemia, lymphoma • CFS • Fibromyalgia • MCS • Autoimmune disease • Inflammatory bowel disease 26 Pollution Effects • Allergies & asthma • Neurodegenerative disease • Endocrine disease • Infertility & Reproductive disorders • Autism 27 Most Contaminated • strawberry • bell pepper • spinach • cherries (US) • peaches • canteloupe (Mexico) 28 Most Contaminated • celery • apples • apricots • green beans • grapes (Chile) • cucumbers 29 Least contaminated vegetables • Onions • Avocado • Sweet corn • Pineapple • Mango • Asparagus • Sweet Peas • Kiwi fruit • Banana • Cabbage • Broccoli • Papaya 30 Less contaminated foods • Organically grown, seasonal produce • Wild caught salmon and sardines • Nuts in shells • Organically raised grains and livestock • Olive & coconut oil 31 General guidelines •Buy organic & local when available •Eat foods when in season •Wash all produce •Eat low on the food chain •Avoid GMO foods •Grow an organic garden 32 Water •Don’t drink unfiltered tap water •Test your home water for contaminants •Best is spring water •Avoid unnecessary bottled water 33 Insulin, Obesity & Cancer • Obesity could account for 14% of all cancer deaths in men and 20% in women – NEJM 2003;348:17 • 60% higher risk of Colon cancer with higher levels of insulin. 90% increase with higher waist circumference. – JNCI 1999;91:1147 34 Insulin & Cancer • Hyperinsulinemia is a risk factor for breast cancer -Br. Ca. Res. Tx. 1996;38:239 – Ca. Causes Control 1996;7:605 • Serum C peptide is higher in breast cancer cases than controls – Int. J Ca. 1992;52:511 • High insulin levels may be the best predictor of whether a woman’s breast cancer recurs – ASCO Mtg 5/23/2000 35 Lifestyle 36 At home • Remove shoes • Keep air circulating • Avoid pressboard, synthetic carpets etc • Use non-toxic cleaners etc • Reduce AC & heat use • Switch to compact fluorescent lights • Use air purifiers and houseplants 37 Mind-Body Connections • Chronic stress depletes your immune system, slows healing and repair and contributes to illness • Reverse effects of stress with sleep, positive activities, and relaxation • Exercise reduces most of the negative effects of stress 38 Exercise • Reduces risk of all major killers (Cancer, heart disease, diabetes, obesity, htn,) • Improves energy • Improves brain function • One in 3 Americans will get cancer. One in 7 active Americans will get cancer • Regular exercise reduces breast cancer risk by 30% (Am J Epid 2003) 39 Plant purifiers • Areca palm • Peace Lily • Rubber plant • Spider plant • English Ivy • Gerbera Daisy • Snake Plant 40 What about supplements? •3 day USDA food consumption studies of 21,500 individuals •Not one person consumed 100% of RDA for all 10 essential nutrients 41 Limitations of RDA •Prevent deficiency dz, not promote health •Doesn’t account for biochemical individuality •Does not meet needs of those with increased demands or illness 42 Vitamin D • Reduces cancer rates at 16 sites (Antica. Res. 2006;26:2687) • Low vit D assoc with increased cancer incidence & mortality ( JNCI 2006) (Am. J. Pub. Health 2006) • Increasing vit D by 25 nm/l assoc with 17% reduction in ca incidence, 29% reduction in ca mortality and 45% reduction in dig system ca mortality (JNCI 2006;98:451) 43 Serum Vit D & breast cancer risk Serum Vit D (nm) RR for breast ca <30 1.0 30-45 0.57 45-60 0.49 60-75 0.43 >75 0.31 Carcinogenesis 2008;29:93 44 Increased Demand for Nutrients • Methionine • (vit. B-6,) • Homocysteine (bad) • (vit. B-6, B-12, Folic acid) • Cysteine, taurine(good) 45 A Good Multivitamin •Vitamin A 5000iu •Mixed Carotenes 10,000-25,000 iu •B vits 10-50 mg •Vitamin C 10003000mg •Vitamin D 400-800 iu •Vitamin E 200-400 iu •Vitamin K 1 mg • • • • • • • • • Calcium 500-1000 mg Magnesium 400-800 Zinc 15-30 mg Copper 1-2 mg Selenium 200 mcg Chromium 200 mcg Iodine 150 mcg Boron 2-3 mgm (?) Iron (?) 46 Putting it all together •Healthy Diet •Don’t smoke •Alcohol in moderation, if any •Stay Active •Maintain Healthy weight •Take time for fun •Sleep •Take high quality vitamins 47 48