Download Colostrum 101

COLOSTRUM 101
An Overview of Nature’s Amazing
Immune-Enhancing & Anti-Aging Superfood
About Sequence Health
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A niche company dedicated to ethical & superior
colostrum
The only genuine 6 hour first milking colostrum supplier
in Canada
Science team: Dr. Richard Cockrum, Dr. Beth Ley & Dr.
Jonn Randel (Canada) & Dr. Sherif Sabry (Egypt)
Aggressive advertising, high quality
educational/promotional tools and strong retail support
Dr. Richard Cockrum
Dr. Beth Ley
What is Colostrum?
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Colostrum is the pre-milk fluid produced by female
mammals prior to birth
Naturally rich in immune and growth factors, it is life’s first
food and can benefit people of all ages
Long history of use in Ayurvedic & Western medicine
Bovine colostrum is almost identical to human colostrum;
it is not species specific and can benefit all mammals
Dairy cows produce more than enough colostrum to
supply human needs without depriving calves of their
essential first food
Why We Need Colostrum
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New strains of bacteria and viruses found resistant to existing
antibiotics and drugs
Ever-increasing levels of chemical pollutants in our food,
water and air resulting in compromised immune systems
Overwhelmed immune systems due to job, family and
environmental stresses
Impaired tissue & muscle repair due to pushing the body
beyond its natural limits
As we age, our bodies produce less and less of the immune
and growth factors essential for optimal health and vitality
What’s in Colostrum?
Bovine colostrum contains many essential nutrients and
bioactive components, identical to those found in milk but at
higher concentrations. These include mainly:
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Immunoglobulins (Igs): mainly IgA, IgG & IgM
Lactoperoxidase (Lp): anti bacterial enzyme
Lysozyme (Lys): anti-infective, gentle oral germicide
Lactoferrin (Lf): anti-infective, antioxidant, iron transporter
a-Lactalbumin (a-Lac): tryptophan provider
Growth factors
Cytokines, nucleosides, vitamins, peptides and
oligosaccharides
Benefits of Colostrum
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Boosts natural resistance to illness/disease and helps fight
off bacterial and viral infection
Protects against auto-immune disorders
Improves state of chronic health problems
Builds lean muscle mass and burns fat
Increases energy and improves memory and mood
Supports cellular growth and repair to slow down the aging
process
IgG
IgG of bovine colostrum prevent, in humans, villous
atrophy and stimulates mucosal healing of patient
suffering from inflammatory gut diseases
They reduce diarrhea symptoms in infants and
protect intestinal mucosa from pathogen bacteria
adhesion. IgGs attacks bacteria and parasites
entering the gut; as IgG has two antigen binding
sites, it recognizes, binds and destroys antigen by
coating the microbe before destruction by the
macrophage. As the attack is located in the
digestive tract, the immune system is not concerned
providing from any immune reaction.
Growth Factors
Growth factors are proteins that play an important role in the regulation of
cell division and tissue proliferation. By binding to receptors on the cell
surface, they activate (or inhibit) cellular proliferation and(or)
differentiation. They are secreted by all kind of tissue and comprise a lot
of different molecules as cytokines, chemokines, interleukines,…
Growth factors such as IGF-1 and IGF2, TGFA and TGF-B are present in
bovine colostrum. Supplementing Human Growth Factors (HGH) is
supposed to slow the aging process. A successful HGH
supplementation requires the preparation of the body for the increased
presence of this substance. The selected ingredients in this unique
formula could address the health of four major areas:
•The brain
•The nervous system
•The energy systems (Adrenals and cellular ATP)
•The body's drainage system
PRPs
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PRP (ProlineRich Polypeptides) is also known as colostrinin,
colostrinine, transfer factor, and other names, but they are all
essentially the same fraction of colostrum. Actually a group of
related polypeptides, PRPs from colostrum have demonstrated
remarkable immunologic and neurologic properties. PRPs
immunological function relate to their ability to modulate and
stabilize many biological processes in the body including
cytokine and immune activity
Pro-rich antimicrobial peptides are a group of linear peptides of
innate immunity isolated from mammals and invertebrates, and
characterized by a high content of proline residues (up to 50%).
Members of this group are predominantly active against Gramnegative bacterial species which they kill by a non-lytic
mechanism, at variance with the majority of the known
antimicrobial peptides.
Importance of First Milking
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Birth is the event that stops the production of
colostrum and starts the production of milk
The sooner after birth colostrum is collected, the
higher its levels of beneficial immune and growth
factors
Only first milking colostrum is used in scientific
research studies as colostrum quality declines
rapidly after birth
Importance of First Milking
15%
% Protein
Colostrum
collected just 24
hours after birth
contains less than
one quarter of the
immune and growth
factors present at
birth
20%
10%
5%
0%
0
3
6
12 24
Hours after birth
Importance of Oral Delivery
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Most pathogens enter body orally
Our oral cavity’s mucosal membranes are
loaded with immuno-receptor sites
Absorption in oral cavity triggers entire
body’s immune system response
Greatest benefits observed in scientific
studies achieved via oral delivery
North America Category Overview
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Total category size in US is about 30 million; in Canada,
approx 1 million but growing.
Category experienced extremely rapid growth since
introduction in 1996 but has slowed in past years due to lack
of awareness, education & promotion
Significant coverage in 2 best-selling books, “Bio-Age” (Brad
King) and “The Food Connection” (Sam Graci) can help
increase demand
Colostrum recently getting some new momentum in
mainstream media in North America.
Sequence Colostrum Products
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Lozenges: Convenient, tasty, featuring slow
mucosal delivery for maximum absorption; our
best seller.
Powder: Pure, potent and versatile; can be
taken orally or applied topically.
Capsules: Same as powder but in more
convenient dosage form
Overcoming Objections
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Does the Colostrum raw material come from 3rd
world?
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Sequel colostrum comes from the finest certified Grade A
dairies from the midwest North America
Colostrum is sourced from hundreds of small, family run farms
with herds of typically less than 50 cows
All cows are pastured and supplementally fed a diet of
grains,legumes, vitamins and minerals
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No growth or milk production hormones are ever given to
pregnant cows as it would cause them to abort
All colostrum batches are tested and certified to be free of
bacteria, heavy metals, nitrates and nitrites and pesticides
Ask to see a certificate of analysis
Overcoming Objections
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Isn’t colostrum just for babies?
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Colostrum has been used for thousands of years in
Ayuverdic medicine for people of all ages
In Western medicine, there are volumes of research
studies proving the benefits of colostrum for people of
all ages
As we age, our bodies gradually produce less of the
immune & growth factors that help fight disease, repair
body tissue and promote energy and vitality.
Colostrum is the only natural source of these lifesupporting immune & growth factors!
Overcoming Objections
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Colostrum is too expensive…
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Colostrum is a proactive approach to healthy
immunity and longevity
Consider the costs of illness and disease
Colostrum can make other supplements and
medications more effective or even obsolete
Just $0.78 a day does the job for most people
What is your long term health worth?