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Standardised Anatomical Nomenclature for Radiotherapy Planning This mapping of anatomical names is based on the Foundational Model of Anatomy1. The reason for this is that the FMA is a formal ontology which means that it embodies the relationships that exist between other anatomic structures. Relationships such as is_inferior_to and is_drained_by are catered for and can be manipulated by computers. Although developed independently, this nomenclature also uses patterns proposed by the ATC 2 but extends it to achieve oncologist-specific aims. The following pattern of naming is determined as a logical sequence to permit standardisation across multiple departments. When DICOM-RT files are finally shared and collated, the use of standardised names will permit meaningful comparison of plans. The document address volumes and contours to reduce confusion. For external sites who may wish to use a different but logical schema, this schema can be used as a template. If the local schema relates back to the FMA number, translation between schemas is enabled. This schema is the Illawarra schema and it means that the hard work has been done already if implemented. The list should be updated as required and redistributed when changed. To this end, the current document will be uploaded online.3 References 1. Structural Informatics Group at the University of Washington. Foundational Model of Anatomy. at <http://sig.biostr.washington.edu/projects/fm/AboutFM.html> 2. Santanam, L. et al. Standardizing Naming Conventions in Radiation Oncology. International journal of radiation oncology, biology, physics 83, 1344–1349 (2012). 3. Miller, A. A. Standardised Nomenclature for Radiation Oncology Planning | Andrew Miller - Academia.edu. at <https://www.academia.edu/5273434/Standardised_Nomenclature_for_Radiation_Oncology_Planning> 4. Ng, M. et al. Australasian Gastrointestinal Trials Group (AGITG) Contouring Atlas and Planning Guidelines for Intensity-Modulated Radiotherapy in Anal Cancer. International Journal of Radiation Oncology*Biology*Physics 83, 1455–1462 (2012). 5. Myerson, R. J. et al. Elective Clinical Target Volumes for Conformal Therapy in Anorectal Cancer: A Radiation Therapy Oncology Group Consensus Panel Contouring Atlas. International Journal of Radiation Oncology*Biology*Physics 74, 824–830 (2009). 6. Grégoire, V. et al. Delineation of the neck node levels for head and neck tumors: A 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines. Radiotherapy and Oncology doi:10.1016/j.radonc.2013.10.010 Professor A. Andrew Miller B.Med, B.Sc, Grad.Dip.Ed, M.Inf.CommTech(Res), FRANZCR, FACHI Senior Staff Specialist, Radiation Oncology Illawarra Cancer Care Centre D:\DROPBOX\DOCUMENTSARTICLES\STANDARDISEDNOMENCLATURE\STANDARD CONTOUR NOMENCLATURE V1.4.DOCX 14/04/2014 9:37 PM Contents 1. 2. 3. 4. 5. 6. 7. 8. 9. Names for Contours of Anatomy Planning Risk Volumes Names for Volumes of Risk The list of Anatomical Names Standardised against the FMA Pelvic & intra-abdominal lymph chains Head & Neck Lymphatic Chains APPENDIX 1 : Use of the Document APPENDIX 2 : Suggestions for scripting APPENDIX 3 : Cheat Sheet 1. Names for Contours of Anatomy All OAR names are in capitals. Some OAR names may be truncated as there is a restriction on the length of names in the DICOM format. The names are specified so that the identifier is unique. Where a unique name can used to represent a single entity, a single word is preferred and substituted (e.g., the hyoid bone becomes 'HYOID'). Likewise, there are standardised additions for laterality (_R/L) and description. The usefulness of this approach derives from the ability of a site to undertake DVH analysis of OARs by using a single report on the DICOM-RT file, and then being able to use that report anywhere without alteration when the OAR names are identical. If the definition of the anatomical structure is in question, please consult the FMA Explorer on the website1 to adjudicate. For the sake of interoperability later, the important part of this table is the FMAID and the definition of this FMA-described organ. The joining of several organ parts (e.g., upper femur) likewise can specify the FMAIDs used. Should you substitute different words for the OAR names here then do three things: i. record the alternate name ii. use the same name for all oncologists within the same unit iii. use the same name all the time within the same unit Where organ contours are being produced, the use of auto-contouring based on CT numbers will result in a reproducible result, more so than free hand drawing. In the coming age of adaptive radiotherapy, this contouring technique is even more meaningful in trying to achieve reproducibility in contouring. 2. Planning Risk Volumes The PRV is a construct which indicates how an organ at risk should be avoided during plan construction. The PRV is always constructed from a contoured organ. The organ is deemed to be ‘at risk’, and predicted to have an impact on plan appearance. Organs at Risk (OAR) can be sub-classified: i. Critical structures which have a maximum dose allowable that may be achieved at the expense of PTV coverage. The normal examples are the SPINALCORD and BRAINSTEM. These organs will have their dose limited to a maximum, usually determined by documents such as those derived from QUANTEC. ii. Expendable structures which have a desired dose but not at the expense of PTV coverage. The normal examples are PAROTID, LENS, KIDNEYS and OESOPHAGUS. These organs may be entirely expendable (e.g., LENS), or partially expendable (KIDNEYS). The PRVs for each are manufactured in different ways iii. CRITICAL STRUCTURE_PRV 1. STRUCTURE_PRV = STRUCTURE + [MOTION EXPANSION] This will mean that the STRUCTURE_PRV may overlap the PTV indicating that the STRUCTURE_PRV should be spared in preference to PTV coverage. iv. EXPENDABLE STRUCTURE_PRV 1. STRUCTURE _PRV = STRUCTURE +[MOTION EXPANSION] – PTV This will mean that the STRUCTURE_PRV will not overlap the PTV, indicating that PTV coverage is preferred. The DVH should be assessed to ensure that the STRUCTURE doses are not excessive (e.g., KIDNEY_TOTAL V18Gy>80%, LUNG_TOTAL V20Gy>60%) 2. Names for Volumes of Risk There are three volumes that require specification. The logical naming of these volumes requires an understanding of definitions of the volumes. a. GTV Each gross tumour volume exists in one of three varieties – primary or Tumour, draining nodes or Nodes, and finally Metastases. The proposal is that these suffixes be added without spacer to the GTV, with numbers used to indicate individual masses if desired. a. GTVp the primary as visualised on the planning imaging scans b. GTVn an involved node (single) or multiple involved nodes where no differentiation is required i. GTVn5 the fifth involved node volumed , if you wish to distinguish it from the first four c. GTVm a single metastasis or multiple metastases where no differentiation is required i. GTVm2 the second metastasis volumed b. CTV Each GTV will have an associated CTV which related to a risk-estimated expansion trimmed to unbreached anatomical boundaries where the risk estimates approach zero. The use of CTV1, CTV2, etc is to be avoided on the basis that it does not define the reason for the CTV, nor its attendant risk. a. CTVp this volume is not a 0.5, 1 or 2 cm expansion of the GTVp, it should be drawn to match the anatomical boundaries distant to the GTVp boundary where the probability of tumour breach falls to zero. b. CTVn this volume is an expansion which is clipped at anatomical boundaries, since the extent of extracapsular extension in in situ nodes is unknown unless there is obvious change in fat density, at present expansions of less than 0.5cm cannot be justified, but whether it is 0,5, 1 or 2cm is a matter of personal risk estimation. It is difficult to see how more than 2cm could be justified if intervening fat is normal on imaging. The volumes should be produced in the same way as CTVp above (i.e., to produce CTVn1, CTVn2, etc.) with one addition. i. CTVn0 this is, the ‘node negative’ neck, which is an anatomical volume in the neck volume which is devoid of any involved nodes and outside the risk assessed expansion on involved nodes. This volume should be drawn around and exclude the CTVn. Modern software allows for overinclusive volumes to be automatically trimmed. It is understood that some oncologists wish to define two CTVn0 areas of moderate and low risk and deliver different doses. In the case of three dose levels define the CTVp/CTVn (high dose), CTVn0a (medium dose) and CTVn0b (low dose). CTVn0a/b will relate to different contours (contour the nodal areas at risk separately). c. CTVm this volume is not a 0.5, 1 or 2 cm expansion of the GTVm, it should be drawn to match the anatomical boundaries distant to the GTVp boundary where the probability of tumour breach falls to zero. c. PTV The definition of the PTV is a geometric expansion of the CTVs which can be grouped automatically in current software with isotropic or anisotropic expansions to form PTVs which are to receive a particular dose. For this reason, the PTV is annotated by a number representing the number of centiGray (cGy) desired in the prescription. The reason for using centiGray revolves around the possible ambiguity of the decimal point in the IT world. a. PTV7000 this is a volume including all CTVs to which the radiation oncologist required a total dose of 70Gy. b. PTV7000_3 this is the same volume where an isotropic expansion margin of 3mm has been used. In the case of an anisotropic volume, no suffix should be used. d. TBV Tumour Bed Volume is optional and a thing volume where the sides of the operative bed have joined or are separated by fluid collection. Notes: 1. ** Under no circumstances is the PTV ever drawn or manipulated by hand. 2. It should be possible to specify PTV construction based on the specified CTVs present in the plan. For example, PTV6000 = CTVp + CTVn1 + CTVn2 +CTVn0 + 3mm PTV7000 = CTVp + CTVn1 +CTVn2 + 3mm It is worth noting that this process will overlap PTV7000 on PTV6000. This has no implications for planning as success in covering the 7000 will also successfully cover the PTV6000. If separate, non-overlapping PTVs are preferred, it is easier to define the highest dose first and then use that PTV as an exclusion volume: #1 #2 PTV7000 = CTVp + CTVn1 +CTVn2 + 3mm PTV6000 = CTVn0 + 3mm – (PTV7000) Change Log V1.4 added mediastinal lymph node groups – LN_MED_1234567810_R/L altered H&N lymph node groups from LN_1a2a345_R/L to LN_HN_1a2a345_R/L V1.3 added hippocampus added TBV The List of Anatomical names standardised against the FMA Standard Nomenclature Root Name OAR Name FMA number (FMAID) Right Pectoral axillary lymphatic chain Right Central axillary lymphatic chain Right Apical axillary lymphatic chain Right Axillary lymphatic chain Left Pectoral axillary lymphatic chain Left Central axillary lymphatic chain Left Apical axillary lymphatic chain Left Axillary lymphatic chain Breast LNAx1_R LN_AX1_R 73252 Lymphatic Primary Region Chest LNAx2_R LNAx3_R LNAx_R LNAx1_L LNAx2_L LNAx3_L LNAx_L BREAST 73262 73264 73249 73253 73263 73265 73250 Lymphatic Lymphatic Chest Chest Chest BRONCHUS Respiratory Chest Carina of trachea Diaphragm Heart Anterior interventricular branch of left coronary artery Lung - lower lobe of left Lung - upper lobe of left Lung - lower lobe of right Lung - middle lobe of right Lung - upper lobe of right Lung CARINA DIAPHRAGM HEART LAD 73124 73125 26661 26662 7465 13295 7088 Endocrine Bronchial tree LN_AX2_R LN_AX3_R LN_AX_R LN_AX1_L LN_AX2_L LN_AX3_L LN_AX_L BREAST_R BREAST_L BRONCHUS_R BRONCHUS_L CARINA DIAPHRAGM HEART A_LAD Respiratory Muscular Vascular Vascular Chest Chest Chest Chest Respiratory Respiratory Respiratory Respiratory Respiratory Respiratory Chest Chest Chest Chest Chest Chest Intestinal Vascular Vascular Skeleton Chest Chest Chest Chest Skeleton Chest Skeleton Chest Skeleton Chest Skeleton Chest LUNG_LLL LUNG_LUL LUNG_RLL LUNG_RML LUNG_RUL LUNG Esophagus Pulmonary artery Pulmonary vein First Rib OESOPHAGUS PULMONARY ARTERY PULMONARY VEIN RIB1 Tenth rib RIB10 Eleventh rib RIB11 Twelfth rib RIB12 Second rib RIB2 LUNG_LLL LUNG_LUL LUNG_RLL LUNG_RML LUNG_RUL LUNG_TOTAL LUNG_R LUNG_L OESOPHAGUS A_PULM V_PULM RIB1_R RIB1_L RIB10_R RIB10_L RIB11_R RIB11_L RIB12_R RIB12_L RIB2_R 3862 7371 7370 7337 7383 7333 68877 7309 7310 7131 66326 66643 7857 7987 8445 8472 8531 8532 8533 8534 7882 Type Secondary Region UpperAbdo Third rib RIB3 Fourth rib RIB4 Fifth rib RIB5 Sixth rib RIB6 Seventh rib RIB7 Eighth rib RIB8 Ninth rib RIB9 Scapula SCAPULA Superior vena cava Trachea Brain Brainstem Cerebellum Cerebrum Optic chiasm Abducens nerve SVC TRACHEA BRAIN BRAINSTEM CEREBELLUM CEREBRUM CHIASM CNVI Spinal accessory nerve CNXI Eyeball EYE Optic nerve OPTICN Orbit ORBIT Pineal body Pituitary gland Pons Spinal cord Hippocampus PINEAL PITUITARY PONS SPINALCORD HIPPOCAMPUS Femur FEMUR BASE RIB2_L RIB3_R RIB3_L RIB4_R RIB4_L RIB5_R RIB5_L RIB6_R RIB6_L RIB7_R RIB7_L RIB8_R RIB8_L RIB9_R RIB9_L SCAPULA_R SCAPULA_L SVC TRACHEA BRAIN BRAINSTEM CEREBELLUM CEREBRUM CHIASM CNVI CNVI_R CNVI_L CNXI_R CNXI_L EYE_R EYE_L OPTICN_R OPTICN_L ORBIT_R ORBIT_L PINEAL PITUITARY PONS SPINALCORD HIPPOCAMPUS HIPPOCAMPUS_R HIPPOCAMPUS_L BOF_R BOF_L 8012 7909 8039 7957 8148 8066 8093 8175 8202 8229 8256 8283 8310 8364 8391 13395 13396 4720 7394 50801 79876 67944 62000 62045 50867 50886 50887 50897 50899 12514 12515 50875 50878 53082 53083 62033 13889 67943 7647 275020 275022 275024 32845 32846 Skeleton Chest Skeleton Chest Skeleton Chest Skeleton Chest Skeleton Chest Skeleton Chest Skeleton Chest Skeleton Chest Vascular Respiratory Neural Neural Neural Neural Neural Neural Chest Chest CNS CNS CNS CNS CNS CNS Neural CNS Neural CNS H&N Neural CNS H&N Neural CNS H&N Neural Neural Neural Neural Neural CNS CNS CNS CNS CNS Skeleton Extremities H&N H&N H&N H&N H&N Femur FEMUR WHOLE Fibula FIBULA Femur FEMUR NECK Humerus HUMERUS Radius RADIUS Femur FEMUR SHAFT Arytenoid cartilage ARYTENOID Atlas Axis Cervical Vertebra Cervical Vertebra Cervical Vertebra Cervical Vertebra Cervical Vertebra Cervical Vertebra Clavicle C1 C2 C3 C4 C5 C6 C7 C8 CLAVICLE Oculomotor nerve CNIII Glossopharyngeal nerve CNIX Facial nerve CNVII Hypoglossal nerve CNXII Cochlea COCHLEA Cricoid cartilage Digastric muscle CRICOID DIGASTRIC Hyoid bone Lacrimal gland HYOID LACRIMAL FEMUR_R FEMUR_L FIBULA FIBULA_R FIBULA_L HOF_R HOF_L HUMERUS_R HUMERUS_L RADIUS_R RADIUS_L SOF_R SOF_L ARYTENOIDs ARYTENOID_R ARYTENOID_L 24474 24475 24479 24480 24481 32842 32843 23130 23131 23464 23465 32848 32849 Skeleton Extremities Skeleton Extremities Skeleton Extremities Skeleton Extremities Skeleton Extremities Skeleton Extremities 55109 55113 55114 Skeleton H&N VB_C1 VB_C2 VB_C3 VB_C4 VB_C5 VB_C6 VB_C7 VB_C8 CLAVICLE_R CLAVICLE_L CNIII_R CNIII_L CNIX CNIX_R CNIX_L CNVII_R CNVII_L CNXII_R CNXII_L COCHLEA_R COCHLEA_L CRICOID DIGASTRIC_R DIGASTRIC_L HYOID LACRIMAL_R LACRIMAL_L 12519 12520 12521 12522 12523 12524 12525 23892 13322 13323 50879 50880 50870 50892 50894 50888 50889 50901 50903 60202 60203 9615 46292 46293 52749 59102 59103 Skeleton Skeleton Skeleton Skeleton Skeleton Skeleton Skeleton Skeleton Skeleton H&N H&N H&N H&N H&N H&N H&N H&N H&N Chest Neural H&N CNS Neural H&N CNS Neural H&N CNS Neural H&N CNS Neural H&N CNS Skeleton Muscular H&N H&N Skeleton Endocrine H&N H&N CNS Larynx Lens LARYNX LENS Mandible Masseter MANDIBLE MASSETER Parotid gland PAROTID Platysma PLATYSMA Pterygoid muscles Lateral pterygoid Pterygoid muscles Medial pterygoid Sternocleidomastoid SCM Submandibular gland SUBMAND Brachial Plexus Thyroid Thyroid cartilage Anal canal Urinary Bladder Large intestine Common iliac artery BRACHIALP THYROID THYROIDCART ANUS BLADDER COLON ILIAC_CA Common iliac vein ILIAC_CV External iliac artery ILIAC_EA External iliac vein ILIAC_EV Internal iliac artery ILIAC_IC Internal iliac vein ILIAC_IV Ilium ILIUM Ischium ISCHIUM Lumbar Vertebra Lumbar Vertebra Lumbar Vertebra Lumbar Vertebra L1 L2 L3 L4 LARYNX LENS_R LENS_L MANDIBLE MASSETER_R MASSETER_L PAROTID_R PAROTID_L PLATYSMA_R PLATYSMA_L PTERYGOIDL_R PTERYGOIDL_L PTERYGOIDM _R PTERYGOIDM _L SCM_R SCM_L SUBMAND_R SUBMAND_L BRACHIALP THYROID THYROID_C ANUS BLADDER COLON A_ILIAC_C_R A_ILIAC_C_L V_ILIAC_C_R V_ILIAC_C_L A_ILIAC_E_R A_ILIAC_E_L V_ILIAC_E_R V_ILIAC_E_L A_ILIAC_I_R A_ILIAC_I_L V_ILIAC_I_R V_ILIAC_I_L ILIUM_R ILIUM_L ISCHIUM_R ISCHIUM_L VB_L1 VB_L2 VB_L3 VB_L4 55097 58242 58243 52748 48997 48998 59797 59798 45739 45740 49016 49017 49012 49013 13408 13409 59802 59803 5906 9603 55099 15703 15900 7201 14765 14766 21387 21388 18806 18807 18885 18886 18809 18810 18887 18888 16590 16591 16593 16594 13072 13073 13074 13075 H&N Neural H&N H&N Skeleton Muscular H&N H&N H&N H&N H&N H&N H&N H&N H&N H&N Muscular H&N H&N H&N H&N Endocrine H&N Intestinal Urinary Intestinal Vascular H&N H&N H&N Pelvis Pelvis Pelvis Pelvis Vascular Pelvis Vascular Pelvis Vascular Pelvis Vascular Pelvis Vascular Pelvis Skeleton Pelvis Skeleton Pelvis Skeleton Skeleton Skeleton Skeleton Pelvis Pelvis Pelvis Pelvis CNS UpperAbdo Lumbar Vertebra Parametrium Vagina Cervix of uterus Uterus Ovary L5 PARAMETRIUM VAGINA CERVIX UTERUS OVARY Bony pelvis PELVIS Peritoneal sac Prostate Penis PERITONEUM PROSTATE PENIS CORPUS CAVERNOSUM CORPUS SPONGIOSUM Pubic bone PUBIS Rectum Sacral Vertebra Sacral Vertebra Sacral Vertebra Sacral Vertebra Sacral Vertebra Sacrum Seminal vesicle Adrenal glands RECTUM S1 S2 S3 S4 S5 SACRUM SV ADRENAL Aorta Small intestine Duodenum Gall bladder Inferior vena cava Kidney AORTA BOWEL DUODENUM GALLB IVC KIDNEY Renal pelvis KPELVIS Liver Pancreas Stomach Ureter LIVER PANCREAS STOMACH URETER Testis TESTIS VB_L5 PARAMETRIUM VAGINA CERVIX UTERUS OVARY_R OVARY_L PELVIS PELVIS_R PELVIS_L PERITONEUM PROSTATE PENIS CAVERNOSUM SPONGIOSUM 13076 77061 19949 17740 17558 7213 7214 16586 20226 20227 9908 9600 9707 75189 19617 Skeleton Gynae Gynae Gynae Gynae Gynae Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis Skeleton Pelvis Intestinal Urinary Urinary Pelvis Pelvis Pelvis PUBIS_R PUBIS_L RECTUM VB_S1 VB_S2 VB_S3 VB_S4 VB_S5 SACRUM SV ADRENAL_R ADRENAL_L AORTA BOWEL DUODENUM GALLB IVC KIDNEY_R KIDNEY_L KIDNEY_TOTAL KPELVIS_R KPELVIS_L LIVER PANCREAS STOMACH URETER_R URETER_L TESTIS_R 16596 16597 14544 13077 13078 13079 13080 13081 16202 19387 15630 15629 3734 7200 7206 7202 10951 7204 7205 Skeleton Pelvis Intestinal Skeleton Skeleton Skeleton Skeleton Skeleton Skeleton Urinary Endocrine Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis UpperAbdo Vascular Intestinal Intestinal Intestinal Vascular Renal UpperAbdo UpperAbdo UpperAbdo UpperAbdo UpperAbdo UpperAbdo Urinary UpperAbdo Intestinal Intestinal Intestinal Urinary UpperAbdo UpperAbdo UpperAbdo UpperAbdo UpperAbdo Chest 264815 15578 15579 7197 7198 7148 17887 17888 7211 Urinary Pelvis Pelvis Scrotum (skin & cremasteric fascia) Vulva (includes mons pubis) Thoracic Duct Lymph nodes – para-aortic (upper T level – lower L level) Lymph nodes – common iliac Lymph nodes – presacral Lymph nodes – external iliac Lymph nodes – internal iliac Lymph nodes – obturator Parametrium SCROTUM VULVA THORACIC DUCT LN_PARAAORTIC_TxLx TESTIS_L SCROTUM VULVA THORACICDUCT LN_PARAAORTIC_TxLx 7212 18252 20462 5031 223899 LN_ILIAC_COM LN_PRESACRAL LN_ILIAC_EXT LN_ILIAC_INT LN_OBT PARAMETRIUM LN_ILIAC_COM LN_PRESACRAL LN_ILIAC_EXT LN_ILIAC_INT LN_OBT PARAMETRIUM 224269 234280 229177 224275 16676 77061 Urinary Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis Pelvis Pelvic & intra-abdominal lymph chains Individual chains with radiological demarcation. Lymphatic Chain FMAID Thoracic duct [5031] THORACICDUCT Lateral aortic lymphatic chains PARAMETRIUM Bottom: common iliac bifurcation (level of CIA ‘carina’) Lateral: medial edge of psoas muscle Posterior: pelvic bones (do not enter nerve canals) Top: common iliac bifurcation (level of CIA ‘carina’) Medial: continuous volume Anterior: peritoneum (thin, <10mm thick) Bottom: Lateral: S1-2 junction common iliac LC Posterior: sacral bones [224275] [16676] LN_OBT Parametrium Top: aortic bifurcation (level of aortic ‘carina’) Medial: no medial border (extend across contralaterally) Anterior: peritoneum (do not include bowel) Top: common iliac bifurcation (level of CIA ‘carina’) Bottom: superior level of mesorectum Medial: peritoneum Lateral: pelvic muscle/bone Anterior: anterior border of artery/vein complex, cease at ‘pelvic brim’ (line connecting anterior pelvic bones) Posterior: mid-distance to internal iliac artery [this is arbitrary], obturator LC LN_ILIAC_INT Obturator lymphatic chain Bottom: aortic bifurcation (level of aortic ‘carina’) Left: lateral edge of psoas muscle Posterior: vertebra [229177] LN_ILIAC_EXT Internal iliac lymphatic chains Top: second lumbar vertebra Right: lateral edge of psoas muscle Anterior: peritoneum [234280] LN_PRESACRAL External iliac lymphatic chains Bottom: second lumbar vertebra Left: aorta Posterior: body of the second lumbar vertebra [224269] LN_ILIAC_COM Sacral lymphatic chain Top: root of the neck Right: right crus of the diaphragm Anterior: aorta [223899] LN_PARAAORTIC Common iliac lymphatic chains Anatomy [none of these entities enter the peritoneal space, mesorectum, muscles or bones] [77061] Top: common iliac bifurcation (level of CIA ‘carina’) Bottom: superior level of mesorectum Medial: peritoneum Lateral: pelvic muscle/bone Anterior: mid-distance to external iliac artery, obturator LC Posterior: anterior aspect of piriformis muscle [between internal & external iliac LC inferiorly] Top: level near superior level of mesorectum posterior to the bladder where vessels start to move medially Bottom: base of seminal vesicles, cervix {will be in the span of the femoral head) Lateral: pelvic side wall muscle/bone Medial: seminal vesicles Anterior: vascular tissue Posterior: mesorectum [very thin posterior to bladder, encompasses vascular tissue] Top: level near superior level of mesorectum posterior to the bladder where vessels start to move medially Bottom: base of seminal vesicles, cervix {will be in the span of the femoral head) Medial: posterior bladder with large vessels Lateral: obturator LC Anterior: posterior bladder wall Posterior: mesorectum 1. LN_PARAAORTIC_TxLx fill in the levels – upper level (“Tx”) and lower level (“Lx”) para-aortic nodes superior: crura of the diaphragms inferior: bifurcation of the aorta (1st slice with common iliac vessels) Since the pelvic nodes are in continuity rather than discrete, multiple areas may be contoured, but still need to be identified. The proposal for naming of combined pelvic lymph nodes is to reduce to 2 groups: 1. PELVIC NODES a. All nodes b. One sided nodes LN_PELVIS_F_EI_ CI_II_O_PS This contour includes ALL the nodes in the pelvis and down to the femoral nodes. This should only be used when the nodes volumed are bilaterally identical. The nodes are centred on the vessels, but do not extend into the muscle, bones or across the peritoneum into the peritoneal cavity which containing bowel (meaning that this contour should not contain any bowel loops). femoral Inferior: starts at ischial tuberosities4 (no definite anatomic level) superior: 1st slice to see acetabulum external iliac inferior: last slice above the acetabulum (midpoint inguinal ligament) superior: 1st slice to see external iliac vessels common iliac superior: 1st slice to see iliac vessels inferior: the slice ABOVE the 1st slice to see internal iliac vessels internal iliac superior: 1st slice to see internal iliac vessels inferior: lack of space between o. internus m and midline organs obturator superior: EI & II vessels inferior: exit of obturator artery outside the pelvis presacral space superior: CI vessels inferior: mesorectum or S3/4 junction LN_PELVIS_ F_EI_ CI_II_O_PS_R/L This contour names the lateralised nodes in the pelvis. Similar to the neck nodes, the regions NOT included should be deleted from the name, e.g., LN_ CI_II_O _R includes the common, internal iliac and obturator nodes on the right. The nodes are centred on the vessels, but do not extend into the muscle, bones or across the peritoneum into the peritoneal cavity which containing bowel (meaning that this contour should not contain any bowel loops). 2. MESORECTUM superior: Inferior: lateral: anorectal junction with surrounding retroperitoneal fat pelvic floor (where fat around rectum is no longer visible)4 outer border of the pelvic floor muscles (the inner margin of ischiorectal fossa)5 In all cases, areas that are NOT volumed have their name removed. The easiest and most sensible way to do this is to decide which nodal areas will be contoured before drawing anything and to adjust names to reflect the decision making. Then do the drawing. The treatment of the external iliac & femoral nodal areas is only likely to occur with perineal malignancy (anus, vulva, lower vagina). Treatment of the mesorectum (MESORECTUM) is only likely to occur with rectal cancer and extensive anal cancers. Head & Neck Lymphatic Chains This naming procedure is adopted to indicate the nodal areas that are being targeted for radiotherapy. Lymphatic Chain Level I SUPERFICIAL Gregoire6 Submental (IA) 1 Submandibular (IB) 2 Facial (IX) 11 Buccal (IX) 11 Level IIa 3 Level IIb 3 Retropharyngeal (VIIa) Parotid (VIII) Mastoid (Xa) 9 10 12 Level II DEEP SUPERFICIAL SUPERFICIAL 4 Level III SUPERFICIAL Level IV Occipital (Xb) Anatomy Divided by the anterior belly of the digastric muscle Top: MANDIBLE (symphysis menti) Medial: Anterior: DIGASTRIC (Medial) Top: MANDIBLE Medial: STYLOHYOID, GENIOGLOSSUS Anterior: MANDIBLE Bottom: superior THYROID_C Lateral: DIGASTRIC (Medial) Posterior: muscle anterior to HYOID Bottom: lowest extent of SUBMAND Lateral: DEEP FASCIA Posterior: posterior SUBMAND, STYLOHYOID_M Top: Bottom: SUBMAND Medial: DEEP FASCIA Lateral: MANDIBLE Anterior: FACIAL_A Posterior: anterior SCM Top: level of zygoma Bottom: bottom of MANDIBLE Medial: oral cavity Lateral: fascial plane under the subcutaneous fat (SMAS) Anterior: Posterior: anterior MASSETER a.k.a “upper deep cervical nodes” Top: skull base Bottom: inferior border of the hyoid Medial: lateral neck muscles Lateral: medial SCM Anterior: posterior SUBMAND Posterior: posterior SCM Top: skull base Bottom: inferior border of the hyoid Medial: lateral neck muscles Lateral: medial SCM Anterior: anterior SCM Posterior: posterior SCM retropharyngeal space between pharynx & vertebral bodies, drains nasopharynx and posterior pharynx predominately around the superficial lobe, draining lateral face, lateral eyelids, anterior/lateral scalp posterior to mastoid process and ear, drains lateral scalp, drains to superficial & deep cervical nodes Top: inferior border of the hyoid Medial: medial vessels Anterior: medial SCM Bottom: inferior border of the cricoid Lateral: neck muscles Posterior: posterior SCM Top: inferior border of the cricoid Medial: medial vessels Anterior: medial SCM Bottom: brachiocephalic vein Lateral: neck muscles Posterior: posterior SCM Top: mastoid Medial: neck muscles Anterior: posterior SCM Top: inferior border of the cricoid Medial: neck muscles Anterior: posterior SCM Lateral supraclavicular fossa Bottom: inferior cricoid cartilage Lateral: neck fascia Posterior: anterior trapezius Bottom: level of sternoclavicular joint Lateral: neck fascia Posterior: anterior trapezius Top: inferior border of the hyoid Medial: Anterior: fascia Bottom: sternal notch Lateral: medial vessels Posterior: aerodigestive tube 12 5 Level V Level VI Va 6 Vb 6 Vc 7 8 The proposal for naming of the H&N lymph nodes is to start with the name – LN_HN_1a1b2a2b3456_rp_fb_p_o_R/L - and for the RO to then remove from the name those parts that will NOT be volumed. This follows the normal pattern of oncological thought in defining at risk areas, where the at-risk volume is decided BEFORE voluming commences. This is therefore the time to adjust names immediately. If these areas are defined initially (before Volumes), then the nodal contour can be used to define the at-risk boundaries for clipping of CTVs to these boundaries. So “LN_ HN_2a2b34_R” would represent a right ipsilateral neck node volume that does not include LN stations 1a, 1b, 5, 6, retropharyngeal, facial parotid or occipital nodes. The anatomical boundaries of the volume should be consistent with the descriptive code provided. If the oncologist desires to use 3 dose levels then during the contouring phase the oncologist would produce two contours with non-overlapping numbers, e.g., LN_ HN_1a1b2a2b3_R and LN_45_R, The first should be used in the definition of CTVn0a and the second used to define CTVn0b. The equations to produce the PTVs would be : PTV7000 = CTVp + CTVn1 +CTVn2 + 3mm PTV6000 = CTVp + CTVn1 + CTVn2 +CTVn0a + 3mm PTV5400 = CTVn0b + 3mm – PTV6000 Mediastinal Lymph Node Chains The delineation of nodal stations in the mediastinum is not, to my knowledge, a commonly undertaken task. Accurate delineation of the nodal regions requires a contrast scan as the appearance of pulmonary vasculature can be deceiving on a plain scan. The thoracic nodal volumes are arranged in three columns – front, middle and back (these divisions are not necessarily reflective of the normal anatomical divisions of the mediastinum so I hesitate to use the proper anatomical terms like anterior). The naming confusingly is top down, i.e., the first nodal group – the hilar nodes – are level 10/11. The uppermost and presumably last involved node behind the upper sternum is level 1. The front column is a sheet wrapped around the anterior mediastinum in front of the vasculature, the middle and back columns form a central core divided along the line of the posterior trachea, and finally the middle column divides under the shadow of the carina. The back column of nodes includes the oesophagus over its entire length, and is split into three levels at the level of the carina with level 8 (below the carina inferiorly to the level of the R middle lobe bronchus and behind the line of the posterior bronchial walls), level 7 (below the carina inferiorly to the level of the R middle lobe bronchus and behind the line of the anterior & posterior bronchial walls) and level 3P (up from the carina to the suprasternal notch where it sits behind the posterior trachea). The middle column of nodes contains the trachea and the tissue around and in front, and is split at the level of the arch of the aorta into level 4_R/L (below the arch of the aorta inferiorly to the R pulmonary artery where mediastinal fat disappears, and in front of the posterior wall of the trachea) and level 1/2 (up from the arch of the aorta to the suprasternal notch superiorly where it contains the brachiocephalic vein moving from behind the left sternoclavicular joint to the R second interspace [angle of Louis], and in behind of the arterial vascular arcade arising from the aortic arch). The front column of nodes has two levels split at the level of the level of the carina into level 6 (from the first slice showing the carina inferiorly to lowest image containing the R pulmonary artery but only around to the midpoint of the aortic ellipse where it junctions with level 5 which occupies the posterior L lateral portion of the aortic ellipse around to the descending aorta and then L pulmonary artery & vein at the hilum) and level 3A (from first slice above the carina to suprasternal notch and anterior to the aortic vascular arcade arising from the aortic arch but not extending laterally past the L subclavian artery). On the left lateral side, level 3A junctions with level 6 on the exposed anterolateral aortic wall behind the L subclavian artery which extends around to the mid-aortic wall, and moves around posteriorly to level 5 (starts under the aortic arch and extends between the aortic limbs, the left pleura and the closest point between the aortic limbs inferiorly to lowest image containing the R pulmonary artery). LEVEL 3A FMAID 5944 Brachiocephalic LN lat - pleurae, not past left subclavian (L6) ant - posterior sternum post - in front of arterial vascular structures & SVC includes L brachiocephalic vein Carina (first slice with separation) LEVEL 6 Inferior aortic arch LEVEL 5 Superior aortic arch (first slice with aortic wall) LEVEL 4R/L lateral R – R pleura & SVC FMAID 5959 anterior - behind arterial vascular Superior tracheobronchial LN arcade, aorta & SVC FMAID 5960 lateral L – line between vascular R Superior tracheobronchial LN structures, junctions LEVEL 5 FMAID 5961 anterior - posterior trachea L Superior tracheobronchial LN R pulmonary artery where mediastinal fat disappears Posterior line of trachea/bronchi Middle Column Suprasternal notch (last slice down before sternal bone) LEVEL 1 / 2 lateral - R pleura to L pleura FMAID 276933 anterior - behind arterial vascular Upper paratracheal LN arcade & SVC posterior - post tracheal wall Midpoint connecting line of arterial vascular arcade, aorta & pulmonary artery Front Column Back Column LEVEL 3P FMAID 276905 superior posterior mediastinum LEVEL 7 FMAID 5962 Inferior tracheobronchial LN “SUBCARINAL” Contains the oesophagus lateral – R & L pleura anterior – line of posterior trachea posterior - anterior vertebral body, aortic arch & descending aorta Carina (first slice with separation) sup - carina LEVEL 8 inf - R ML bronchus FMAID 12784 ant - anterior Esophageal LN bronchial walls post - posterior bronchial walls lat - medial bronchial walls Contains the oesophagus lateral – R & L pleura; aortic arch & descending aorta ant –posterior trachea/bronchi post - anterior vertebral body, level of R middle lobe bronchus A suggested Contouring Method in discrete steps 1. Outline the soft tissue component in the following manner: a. Draw a line starting from the junction of the R ANTERIOR VERTEBRAL BODY and the R PLEURA, i. contour the PARIETAL PLEURA to the level of the POSTERIOR WALL OF THE TRACHEA, ii. turn left and contour across the POSTERIOR TRACHEA until the L PLEURA is reached, iii. turn inferiorly and contour the PARIETAL PLEURA or RIGHT VASCULAR WALL to reach the junction of the L ANTERIOR VERTEBRAL WALL and the L PLEURA iv. draw across the bony margin of the ANTERIOR VERTEBRAL BODY to complete the volume b. Apply this procedure i. to produce LEVEL 3P from SSN down to CARINA ii. from the CARINA inferiorly 1. produce LEVEL 8 from CARINA down to LEVEL OF R MIDDLE LOBE BRONCHUS using the same method 2. produce LEVEL 7 by returning to the CARINA; contour the subcarinal area by drawing a line a. From the medial wall of the RIGHT MAIN BRONCHUS anteriorly to reach the line joining the ANTERIOR WALLS OF THE R&L MAIN BRONCHI b. turn left to trace this imaginary line to reach the wall of the LEFT MAIN BRONCHUS c. turn posteriorly and outline the MEDIAL WALL of the L MAIN BRONCHUS d. turn right to trace the imaginary line connecting the POSTERIOR WALLS OF THE R&L MAIN BRONCHI to reach the wall of the RIGHT MAIN BRONCHUS e. turn anterior to outline the remaining MEDIAL WALL of the R MAIN BRONCHUS f. repeat this contour from CARINA down to LEVEL OF R MIDDLE LOBE BRONCHUS 2. Returning to the SUPRASTERNAL NOTCH, outline the soft tissue component below: a. Draw a line from the MID-POSTERIOR STERNUM to the right to meet the PLEURA or SVC b. Draw a line down and across the anterior SVC wall to the midpoint of the vascular arcade (anterior SVC > aortic arch vessels > aortic arch > descending aorta > pulmonary trunk > left pulmonary vessels c. Draw a connected line following the L pleura up to the POSTERIOR STERNUM and back to meet the point of origin d. Divide this volume into 3 LEVELS: i. Tissue medial to the most lateral vessel seen on the vascular arcade ( starts with L SUBCLAVIAN ARTERY) is LEVEL 3A (this contains the entire L BRACHIOCEPHALIC VEIN) ii. Tissue lying lateral on the AORTIC ARCH above the INFERIOR AORTIC ARCH is LEVEL 6 (usually this lies anterior to the MIDPLANE of the AORTA) iii. At the level of the INFERIOR AORTIC ARCH, all inferior tissue is LEVEL 5 (this is lying posterior to the MIDPLANE of the AORTA and anterior to the DESCENDING AORTA (also lateral to the midpoints of these vessels) APPENDIX 1 : Use of the Document Departmental The departmental group responsible for introduction of protocols should review the document and approve it. A governance radiation oncologist should be nominated to manage the present status of the document, or accept that the default document will be the default. All scripting of names in the TPS should be reviewed and updated to the standard and verified by the Governance RO. Personal The most logical way to produce contours and volumes is to follow this pattern. Note that initially ROIs are freehanded, and then once the CTVp is complete, the rest are geometric manipulations: 1. Produce all of the contours first, including nodal groups For the nodal areas required, generate contours of nodal areas with anatomical names by freehand or segmentation. If 3 dose levels will be used, contour two nodal areas with nonoverlapping names. 2. Produce the volumes in the order a. Produce the GTVp >Vn Usually achieved by freehand drawing on sim CT b. Produce CTVp i. Transform GTVp into CTVp 1. Expand with NO margin to create the CTVp, and then, 2. Freehand modification of the CTVp to match appropriate radial anatomical planes (bone, air, lung, fascia, muscle) c. Produce CTVn i. Expand GTVn to CTVn 1. With margin (0.3-0.5?) 2. excluding external to LN contours 3. excluding internal of CTVp d. Produce CTVn0 i. Expand LN contour into CTVn0a/b 1. With NO margin 2. Excluding internal of CTVp 3. Excluding internal of CTVn e. Produce PTV_highdose i. Expand CTVp + CTVn 1. With margin (0.3mm) 2. Rename to PTVxxxx f. Produce PTV_middose i. Expand CTVp + CTVn + CTVn0a 1. With margin (0.3mm) 2. Rename to PTVyyyy g. Produce PTV lowdose i. Expand CTVn0b 1. With margin (0.3mm) 2. Exclude PTVyyyy (middose) APPENDIX 2 : Suggestions for scripting Brain All names H&N Neuroaxis Base of Brain All names Upper H&N Lower H&N Chest H&N bones H&N glands H&N muscles All names Breast Lung Oesophagus Chest bones UpperAbdo All names Major names BRAIN, BRAINSTEM, CEREBELLUM, CHIASM, EYE_R, EYE_L, OPTICN_R, OPTICN_L, ORBIT_R, ORBIT_L, SPINALCORD, Minor names CEREBRUM, CNVI, CNVI_R, CNVI_L, CNXI_R , CNXI_L, PINEAL, PITUITARY, PONS, BRAIN, BRAINSTEM, CEREBELLUM, CEREBRUM, PINEAL, PONS, SPINALCORD, HIPPOCAMPUS CHIASM, CNVI, CNVI_R, CNVI_L, CNXI_R , CNXI_L, EYE_R, EYE_L, OPTICN_R, OPTICN_L, ORBIT_R, ORBIT_L, PITUITARY Major names COCHLEA_R, COCHLEA_L, LACRIMAL_R, LACRIMAL_L, LARYNX, LENS_R, LENS_L, MANDIBLE, PAROTID_R, PAROTID_L, SUBMAND_R, SUBMAND_L, THYROID, LN_HN_1a1b2a2b3456_rp_fb_p_o_R/L Minor names ARYTENOID, ARYTENOID_R, ARYTENOID_L, C1, C2, C3, C4, C5, C6, C7, C8, CLAVICLE_R, CLAVICLE_L, CNIII_R, CNIII_L, CNIX_R , CNIX_L, CNVII_R, CNVII_L, CNXII_R , CNXII_L, CRICOID, DIGASTRIC_R, DIGASTRIC_L, HYOID, MASSETER_R, MASSETER_L, PLATYSMA_R, PLATYSMA_L, PTERYGOIDL_R, PTERYGOIDL_L, PTERYGOIDM _R, PTERYGOIDM _L, SCM_R, SCM_L, THYROID_C C1, C2, C3, C4, C5, C6, C7, C8, CNIII_R, CNIII_L, CNIX_R , CNIX_L, CNVII_R, CNVII_L, CNXII_R , CNXII_L, COCHLEA_R, COCHLEA_L, DIGASTRIC_R, DIGASTRIC_L, HYOID, LACRIMAL_R, LACRIMAL_L, LENS_R, LENS_L, MANDIBLE, MASSETER_R, MASSETER_L, PAROTID_R, PAROTID_L, PTERYGOIDL_R, PTERYGOIDL_L, PTERYGOIDM _R, PTERYGOIDM _L, SUBMAND_R, SUBMAND_L ARYTENOID, ARYTENOID_R, ARYTENOID_L, C1, C2, C3, C4, C5, C6, C7, C8, CRICOID, HYOID, LARYNX, MANDIBLE, PAROTID_R, PAROTID_L, SCM_R, SCM_L, SUBMAND_R, SUBMAND_L, THYROID, THYROID_C VB_C1, VB_C2, VB_C3, VB_C4, VB_C5, VB_C6, VB_C7, VB_C8, CLAVICLE_R, CLAVICLE_L, HYOID, MANDIBLE LACRIMAL_R, LACRIMAL_L, PAROTID_R, PAROTID_L, SUBMAND_R, SUBMAND_L, THYROID DIGASTRIC_R, DIGASTRIC_L, MASSETER_R, MASSETER_L, PLATYSMA_R, PLATYSMA_L, PTERYGOIDL_R, PTERYGOIDL_L, PTERYGOIDM _R, PTERYGOIDM _L, SCM_R, SCM_L Major names LN_AX_R, LN_AX_L, BREAST_R, BREAST_L, HEART, LUNG_TOTAL, LUNG_R, LUNG_L, OESOPHAGUS, Minor names BRONCHUS_R, BRONCHUS_L, CARINA, DIAPHRAGM, LUNG_LLL, LUNG_LUL, LUNG_RLL, LUNG_RML, LUNG_RUL, PULM_A, PULM_V, RIB1_R, RIB1_L, RIB10_R, RIB10_L, RIB11_R, RIB11_L, RIB12_R, RIB12_L, RIB2_R, RIB2_L, RIB3_R, RIB3_L, RIB4_R, RIB4_L, RIB5_R, RIB5_L, RIB6_R, RIB6_L, RIB7_R, RIB7_L, RIB8_R, RIB8_L, RIB9_R, RIB9_L, SCAPULA_R , SCAPULA_L, SVC, TRACHEA, A_LAD LN_AX1_R, LN_AX2_R, LN_AX3_R, LN_AX1_L, LN_AX2_L, LN_AX3_L, BREAST_R, BREAST_L, HEART, A_LAD, LUNG_TOTAL, LUNG_R, LUNG_L, OESOPHAGUS BRONCHUS_R, BRONCHUS_L, CARINA, DIAPHRAGM, HEART, LUNG_LLL, LUNG_LUL, LUNG_RLL, LUNG_RML, LUNG_RUL, LUNG_TOTAL, LUNG_R, LUNG_L, OESOPHAGUS, PULM_A, PULM_V, SVC, TRACHEA HEART, LUNG_TOTAL, LUNG_R, LUNG_L, OESOPHAGUS RIB1_R, RIB1_L, RIB10_R, RIB10_L, RIB11_R, RIB11_L, RIB12_R, RIB12_L, RIB2_R, RIB2_L, RIB3_R, RIB3_L, RIB4_R, RIB4_L, RIB5_R, RIB5_L, RIB6_R, RIB6_L, RIB7_R, RIB7_L, RIB8_R, RIB8_L, RIB9_R, RIB9_L, SCAPULA_R , SCAPULA_L Major names BOWEL, KIDNEY_R, KIDNEY_L, LIVER, LN_PARAAORTIC_TxLx Minor names ADRENAL_R, ADRENAL_L, AORTA, DUODENUM, GALLB, IVC, KPELVIS_R, KPELVIS_L, PANCREAS, STOMACH, URETER_R, URETER_L Pelvis All names Anus Bladder Gynae Prostate Rectum Pelvic bones Extremities Major names ANUS, BLADDER, COLON, PARAMETRIUM, PERITONEUM, PROSTATE, RECTUM, SV, LN_PARAAORTIC_TxLx, LN_ F_EI_ CI_II_O_PS_R/L, MESORECTUM Minor names A_ILIAC_C_R, A_ILIAC_C_L,V_ ILIAC_C_R, C_ILIAC_C_L, A_ILIAC_E_R, A_ILIAC_E_L, V_ILIAC_E_R, V_ ILIAC_E_L, A_ILIAC_I_R, A_ILIAC_I_L, V_ILIAC_I_R, V_ILIAC_I_L, ILIUM_R, ILIUM_L, ISCHIUM_R, ISCHIUM_L, L1, L2, L3, L4, L5, VAGINA, CERVIX, UTERUS, PELVIS, PELVIS_R , PELVIS_L, CAVERNOSUM, SPONGIOSUM, PUBIS_R, PUBIS_L, S1, S2, S3, S4, S5, SACRUM, SV_R , SV_L ANUS, BLADDER A_ILIAC_C_R, A_ILIAC_C_L,V_ ILIAC_C_R, C_ILIAC_C_L, A_ILIAC_E_R, A_ILIAC_E_L, V_ILIAC_E_R, V_ ILIAC_E_L, A_ILIAC_I_R, A_ILIAC_I_L, V_ILIAC_I_R, V_ILIAC_I_L, PERITONEUM, RECTUM BLADDER, A_ILIAC_C_R, A_ILIAC_C_L,V_ ILIAC_C_R, C_ILIAC_C_L, A_ILIAC_E_R, A_ILIAC_E_L, V_ILIAC_E_R, V_ ILIAC_E_L, A_ILIAC_I_R, A_ILIAC_I_L, V_ILIAC_I_R, V_ILIAC_I_L, PERITONEUM, RECTUM BLADDER, A_ILIAC_C_R, A_ILIAC_C_L,V_ ILIAC_C_R, C_ILIAC_C_L, A_ILIAC_E_R, A_ILIAC_E_L, V_ILIAC_E_R, V_ ILIAC_E_L, A_ILIAC_I_R, A_ILIAC_I_L, V_ILIAC_I_R, V_ILIAC_I_L, PARAMETRIUM, VAGINA, CERVIX, UTERUS, PERITONEUM BLADDER, A_ILIAC_C_R, A_ILIAC_C_L,V_ ILIAC_C_R, C_ILIAC_C_L, A_ILIAC_E_R, A_ILIAC_E_L, V_ILIAC_E_R, V_ ILIAC_E_L, A_ILIAC_I_R, A_ILIAC_I_L, V_ILIAC_I_R, V_ILIAC_I_L, PERITONEUM, PROSTATE, CAVERNOSUM, SPONGIOSUM, RECTUM, SV_R , SV_L BLADDER, COLON A_ILIAC_C_R, A_ILIAC_C_L,V_ ILIAC_C_R, C_ILIAC_C_L, A_ILIAC_E_R, A_ILIAC_E_L, V_ILIAC_E_R, V_ ILIAC_E_L, A_ILIAC_I_R, A_ILIAC_I_L, V_ILIAC_I_R, V_ILIAC_I_L, PERITONEUM, RECTUM ILIUM_R, ILIUM_L, ISCHIUM_R, ISCHIUM_L, L1, L2, L3, L4, L5, PELVIS, PELVIS_R, PELVIS_L, PUBIS_R, PUBIS_L, S1, S2, S3, S4, S5, SACRUM BOF_R, BOF_L, FEMUR_R, FEMUR_L, FIBULA , FIBULA_R, FIBULA_L, HOF_R, HOF_L, HUMERUS_R , HUMERUS_L, RADIUS_R , RADIUS_L, SOF_R, SOF_L APPENDIX 3 : Cheat Sheet VOLUMES GTV GTVpx, GTVnx versions permitted (x=1,2,3) CTV CTVpx, CTVnx, CTVn0 versions permitted (x=1,2,3) PTV Dose levels PTVxxxx_m (x = cGy, m = mm) CONTOURS Standard Nomenclature OAR Name BONES First Rib Tenth rib Eleventh rib Twelfth rib Second rib Third rib Fourth rib Fifth rib Sixth rib Seventh rib Eighth rib Ninth rib Scapula Femur (entire) Femur (head) Femur (shaft) Femur (base/distal) Fibula RIB1_R, RIB1_L RIB10_R, RIB10_L RIB11_R, RIB11_L RIB12_R, RIB12_L RIB2_R, RIB2_L RIB3_R, RIB3_L RIB4_R, RIB4_L RIB5_R, RIB5_L RIB6_R, RIB6_L RIB7_R, RIB7_L RIB8_R, RIB8_L RIB9_R, RIB9_L SCAPULA_R, SCAPULA_L FEMUR_R, FEMUR_L HOF_R, HOF_L SOF_R, SOF_L BOF_R, BOF_L FIBULA_R, FIBULA_L Humerus Radius Atlas Axis Cervical Vertebra Cervical Vertebra Cervical Vertebra Cervical Vertebra Cervical Vertebra Cervical Vertebra Clavicle Pubic bone Rectum Mandible Ilium Ischium Lumbar Vertebra Lumbar Vertebra Lumbar Vertebra Lumbar Vertebra Lumbar Vertebra Bony pelvis Sacral Vertebra Sacral Vertebra Sacral Vertebra Sacral Vertebra Sacral Vertebra Sacrum HUMERUS_R, HUMERUS_L RADIUS_R, RADIUS_L VB_C1 VB_C2 VB_C3 VB_C4 VB_C5 VB_C6 VB_C7 VB_C8 CLAVICLE_R, CLAVICLE_L PUBIS_R, PUBIS_L RECTUM MANDIBLE ILIUM_R, ILIUM_L ISCHIUM_R, ISCHIUM_L VB_L1 VB_L2 VB_L3 VB_L4 VB_L5 PELVIS, PELVIS_R , PELVIS_L VB_S1 VB_S2 VB_S3 VB_S4 VB_S5 SACRUM NEURAL Brain Brainstem Cerebellum Cerebrum Optic chiasm Abducens nerve Spinal accessory nerve BRAIN BRAINSTEM CEREBELLUM CEREBRUM CHIASM CNVI, CNVI_R, CNVI_L CNXI_R , CNXI_L Eyeball Optic nerve Orbit Pineal body Pituitary gland Pons Spinal cord Oculomotor nerve Glossopharyngeal nerve Facial nerve Hypoglossal nerve Cochlea Brachial Plexus EYE_R, EYE_L OPTICN_R, OPTICN_L ORBIT_R, ORBIT_L PINEAL PITUITARY PONS SPINALCORD CNIII_R, CNIII_L CNIX, CNIX_R , CNIX_L CNVII_R, CNVII_L CNXII_R , CNXII_L COCHLEA_R, COCHLEA_L BRACHIALP LYMPHATICS Pectoral axillary lymphatic chain LN_AX1_R, LN_AX1_L Central axillary lymphatic chain LN_AX2_R, LN_AX2_L Apical axillary lymphatic chain LN_AX3_R, LN_AX3_L Axillary lymphatic chain LN_AX_R, LN_AX_L Cervical lymphatic chain LN_HN_1a1b2a2b3456_rp_f_p_o (add _R/L at end) Mesorectal lymphatics MESORECTUM Pelvic lymphatics LN_PELVIS_EI_F_ CI_II_O_PS (add _R/L at end) Para-aortic lymphatics LN_PARAAORTIC_TxLx Mediastinal lymphatics LN_MED_1234567810_R/L Thoracic Duct THORACICDUCT Common iliac lymphatics LN_ILIAC_COM Presacral lymphatics LN_PRESACRAL External iliac lymphatics LN_ILIAC_EXT Internal iliac lymphatics LN_ILIAC_INT Obturator lymphatics LN_OBT Parametrium PARAMETRIUM VASCULAR Pulmonary artery Pulmonary vein Superior vena cava Common iliac artery Common iliac vein External iliac artery External iliac vein Internal iliac artery Internal iliac vein Aorta Inferior vena cava THORAX Breast Bronchial tree Carina of trachea Diaphragm Heart Lung - lower lobe of left Lung - upper lobe of left Lung - lower lobe of right Lung - middle lobe of right Lung - upper lobe of right Lung Esophagus Trachea HEAD &NECK Arytenoid cartilage Cricoid cartilage Digastric muscle Hyoid bone Lacrimal gland Larynx Lens Masseter Mucosa Parotid gland A_PULM V_PULM SVC A_ILIAC_C_R, A_ILIAC_C_L V_ILIAC_C_R, V_ILIAC_C_L A_ILIAC_E_R, A_ILIAC_E_L V_ILIAC_E_R, V_ILIAC_E_L A_ILIAC_I_R, A_ILIAC_I_L V_ILIAC_I_R, V_ILIAC_I_L AORTA IVC BREAST_R, BREAST_L BRONCHUS_R, BRONCHUS_L CARINA DIAPHRAGM HEART LUNG_LL_L LUNG_UL_L LUNG_LL_R LUNG_ML_R LUNG_UL_R LUNG_TOTAL, LUNGs LUNG_R, LUNG_L OESOPHAGUS TRACHEA ARYTENOID, ARYTENOID_R, ARYTENOID_L CRICOID DIGASTRIC_R. DIGASTRIC_L HYOID LACRIMAL_R, LACRIMAL_L LARYNX LENS_R, LENS_L MASSETER_R, MASSETER_L MUCOSA PAROTID_R, PAROTID_L Platysma Pterygoid muscles (Lateral) Pterygoid muscles (medial) Sternocleidomastoid Submandibular gland Thyroid Thyroid cartilage ABDOMEN Peritoneal sac Adrenal glands Small intestine Duodenum Gall bladder Kidney Renal pelvis Liver Pancreas Stomach PELVIS Anal canal Urinary Bladder Large intestine Parametrium Vagina Cervix of uterus Uterus Ovary Prostate Penis Seminal vesicle Ureter Testis Scrotum PLATYSMA_R, PLATYSMA_L PTERYGOIDL_R PTERYGOIDL_L PTERYGOIDM _R PTERYGOIDM _L SCM_R, SCM_L SUBMAND_R, SUBMAND_L THYROID THYROID_C PERITONEUM ADRENAL_R, ADRENAL_L BOWEL DUODENUM GALLB KIDNEY_R, KIDNEY_L KIDNEY_TOTAL KPELVIS_R, KPELVIS_L LIVER PANCREAS STOMACH ANUS BLADDER COLON PARAMETRIUM VAGINA CERVIX UTERUS OVARY_R, OVARY_L PROSTATE PENIS, CAVERNOSUM, SPONGIOSUM, SPONGIOSUM_R, SPONGIOSUM_L SV_R , SV_L URETER_R , URETER_L TESTIS_R, TESTIS_L SCROTUM Vulva VULVA