Download ANTI-BACTERIAL ANTI-INFLAMMATORY ANTI

ANTI-BACTERIAL
ANTI-INFLAMMATORY
ANTI-FUNGAL
The triple-action treatment that’s effective,
easy and beneficial to your business.
TRESADERM (thiabendazole-dexamethasone-neomycin sulfate)
TRESADERM® (thiabendazole-dexamethasone-neomycin sulfate)
THE
THE SOLUTION
SOLUTION IS
IS
TRESADERM® (thiabendazole-dexamethasone-neomycin sulfate)
THE
SOLUTION
IS
IS
Ringworm
Otitis Externa • Flea Allergy Dermatitis • Hot Spots • Cutaneous Fungal Infections • Focal Pyoderma • Ringworm
Otitis Externa • Flea Allergy Dermatitis • Hot Spots • Cutaneous Fungal Infections • Focal Pyoderma • Ringworm
TRESADERM® (thiabendazole-dexamethasone-neomycin sulfate)
THE SOLUTION IS
The underlying cause of a pet’s dermatosis can be difficult to diagnose. And while skin
rashes and hot spots may seem like minor irritations to pet owners, they can actually have
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treatment
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the underlying cause is unclear. Here are some of the ways in which TRESADERM treats
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cause
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in which
TRESADERM
treats • Ringworm
Otitis
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Cutaneous
Infections
• Hot
• of
• Focal Pyoderma
the underlying
conditions
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patients
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the conditions that can make your patients miserable:
Otitis Externa
Cutaneous
Infections
• Flea Allergy
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ANTI-BACTERIAL
ANTI-INFLAMMATORY
ANTI-FUNGAL
neomycin
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corticosteroid, reduces inflammation
causes of mycotic dermatoses.
skin infections.
and relieves
pain and itching.
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when
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reduces swelling
the conditions
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make and
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OTITIS
EXTERNA
the underlying cause is unclear. Here are some
of the ways in which TRESADERM
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infections
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• controls
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relieves itching
can
• controls secondary infections
TRESADERM is a true solution, not an
FOCAL
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•FOCAL
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OTITIS
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• canal
reduces
inflammation
focal
pyoderma
clumping in an animal’s fur.
OTITISorEXTERNA
• kills bacteria
that
cause
otitis externa
• eases
pain
and
discomfort
reduces
inflammation
• kills bacteria that cause otitis externa
• relieves
itching
• eases
pain and discomfort
HOT
SPOTSinfections
• controls
secondary
SECONDARY INFECTIONS
DUE TO EAR MITES
TRE
oint
to a
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• kills the opportunistic organisms that
feed on ear mite infections
• relieves itching and discomfort
• relieves itching
•cools
controls
secondary infections
•HOT
hot spots
SPOTS
FLEA ALLERGY DERMATITIS
• reduces
cools hotinflammation
spots
• fights
secondary
bacterial
reduces inflammation
FOCAL
PYODERMA
and
fungal
infections
• fights secondary bacterial
• fights pruritus
FOCAL PYODERMA
•and
killsfungal
pathogens
that cause
infections
• kills pathogens
that
cause
focal pyoderma
Important
Safety
Information:
focal pyoderma
TRESADERM
is for
topical use only in dogs and cats. On rare
• reducesSafety
inflammation
Important
Information:
• reduces
inflammation
occasions,
application
of theuse
product
result
erythema
or
• eases pain and
discomfort
TRESADERM
is for
topical
only inmay
dogs
andincats.
On rare
in
the
treated
area.
Discomfort
in
the
treated
area
• easesdiscomfort
pain
and
discomfort
occasions, application of the product may result in erythema or
can
last from
to 48
hours.
discomfort
in 24
thehours
treated
area.
Discomfort in the treated area
HOT
SPOTS
can last from 24 hours to 48 hours.
HOT SPOTS
• cools hot spots
• reduces
• cools hot
spots inflammation
• fights secondary bacterial
and fungal infections
• reduces inflammation
xtp239707_TresadermDetailer8.5x11fld_rsg.indd 3-4
• allows affected area to heal
• helps prevent secondary bacterial infection
DERMATOPHYTOSIS
(RINGWORM)
• controls the dermatophytes that can
cause hair loss and scaly/crusty skin in
dogs and cats
• effective against the three dermatophyte
species that cause 99% of ringworm
infections in dogs and cats1
xtp239707_TresadermDetailer8.5x11fld_rsg.indd 3-4
• fights secondary bacterial
and fungal
infections
Important
Safety Information:
TRESADERM is for topical use only in dogs and cats. On rare
occasions, application of the product may result in erythema or
Important
Safety Information:
discomfort
in the treated area. Discomfort in the treated area
TRESADERM
isfrom
for topical
can last
24 hours use
to 48only
hours.in dogs and cats. On rare
occasions, application of the product may result in erythema or
discomfort in the treated area. Discomfort in the treated area
can last from 24 hours to 48 hours.
xtp239707_TresadermDetailer8.5x11fld_rsg.indd 3-4
AN
neo
AN
that
4/6/15 1:55 PM
ANTI-BACTERIAL
ANTI-INFLAMMATORY
• not absorbed through skin
• acts as a potent steroid
• rarely allergenic
• relieves pain
• effective against gram-positive and
gram-negative bacteria
• quickly reduces swelling
neomycin sulfate quickly kills bacteria
that can cause otitis externa and
common skin infections.
dexamethasone, a fast-acting
corticosteroid, reduces inflammation
and relieves pain and itching.
• alleviates itching
TRESADERM is a true solution, not an
ointment or a salve. That makes it easier
to administer, with no clogging in the ear
canal or clumping in an animal’s fur.
ANTI-FUNGAL
thiabendazole treats the most common
causes of mycotic dermatoses.
• helps treat fungal skin conditions and
otitis externa
• helps prevent fungal overgrowth
when bacteria are eliminated
• effective against the three dermatophyte
species that cause 99% of ringworm
infections in dogs and cats1
SECONDARY INFECTIONS
DUE TO EAR MITES
• kills the opportunistic organisms that
feed on ear mite infections
• relieves itching and discomfort
FLEA ALLERGY DERMATITIS
• fights pruritus
• allows affected area to heal
• helps prevent secondary bacterial infection
DERMATOPHYTOSIS
(RINGWORM)
• controls the dermatophytes that can
cause hair loss and scaly/crusty skin in
dogs and cats
• effective against the three dermatophyte
species that cause 99% of ringworm
infections in dogs and cats1
GOOD MEDICINE. GOOD BUSINESS.
When it comes to skin conditions in cats and dogs,
veterinarians have been reaching for TRESADERM for
more than 30 years. But it’s more than just good medicine –
it’s good business, too. As an excellent choice for so many
common ear and skin conditions in both dogs and cats,
TRESADERM is the one solution you can count on to
meet your clinic’s unique stocking challenges.
• Indicated for both acute and chronic dermatoses
of multiple origins
• Effective against otitis externa
• Available in two convenient sizes: 7.5 mL and 15 mL
• Has non-greasy formula
• Is easy to apply; ideal for use at home, as well as in clinic
TRESADERM (thiabendazole-dexamethasone-neomycin sulfate solution) Dermatologic Solution CAUTION: Federal (U.S.A.) law restricts this drug to use by or on
the order of a licensed veterinarian. DESCRIPTION: Dermatologic Solution TRESADERM® (thiabendazole-dexamethasone-neomycin sulfate solution) contains the
following active ingredients per ml: 40 mg thiabendazole, 1 mg dexamethasone, 3.2 mg neomycin (from neomycin sulfate). Inactive ingredients: glycerin, propylene
glycol, purified water, hypophosphorous acid, calcium hypophosphite; about 8.5% ethyl alcohol and about 0.5% benzyl alcohol. INDICATIONS:Dermatologic
solution TRESADERM is indicated as an aid in the treatment of certain bacterial, mycotic, and inflammatory dermatoses and otitis externa in dogs and cats. Both
acute and chronic forms of these skin disorders respond to treatment with TRESADERM. Many forms of dermatosis are caused by bacteria (chiefly Staphylococcus
aureus, Proteus vulgaris and Pseudomonas aeruginosa). Moreover, these organisms often act as opportunistic or concurrent pathogens that may complicate
already established mycotic skin disorders, or otoacariasis caused by Otodectes cynotis. The principal etiologic agents of dermatomycoses in dogs and cats are
species of the genera Microsporum and Trichophyton. The efficacy of neomycin as an antibacterial agent, with activity against both gram-negative and grampositive pathogens, is well documented. Detailed studies in various laboratories have verified the significant activity thiabendazole displays against the important
dermatophytes. Dexamethasone, a synthetic adrenocorticoid steroid, inhibits the reaction of connective tissue to injury and suppresses the classic inflammatory
manifestations of skin disease. The formulation for TRESADERM combines these several activities in a complementary form for control of the discomfort and
direct treatment of dermatitis and otitis externa produced by the above-mentioned infectious agents. DOSAGE AND ADMINISTRATION: Prior to the administration
of Dermatologic Solution TRESADERM, remove the ceruminous, purulent or foreign materials from the ear canal, as well as the crust which may be associated
with dermatoses affecting other parts of the body. The design of the container nozzle safely allows partial insertion into the ear canal for ease of administration.
The amount to apply and the frequency of treatment are dependent upon the severity and extent of the lesions. Five to 15 drops should be instilled in the ear twice
daily. In treating dermatoses affecting other than the ear the surface of the lesions should be well moistened (2 to 4 drops per square inch) with Dermatologic
Solution TRESADERM twice daily. The volume required will be dependent upon the size of the lesion. Application of TRESADERM should be limited to a period of
not longer than one week. PRECAUTIONS: On rare occasions dogs may be sensitive to neomycin. In these animals, application of the drug will result in erythema of
the treated area, which may last for 24 to 48 hours. Also, evidence of transient discomfort has been noted in some dogs when the drug was applied to fissured or
denuded areas. The expression of pain may last 2 to 5 minutes. Application of Dermatologic Solution TRESADERM should be limited to periods not longer than one
week. While systemic side effects are not likely with topically applied corticosteroids, such a possibility should be considered if use of the solution is extensive
and prolonged. If signs of salt and water retention or potassium excretion are noticed (increased thirst, weakness, lethargy, oliguria, gastrointestinal disturbances
or tachycardia), treatment should be discontinued and appropriate measures taken to correct the electrolyte and fluid imbalance. Store in a refrigerator 36°-46°F
(2°-8°C). WARNING: For topical use in dogs and cats. Avoid contact with eyes. Keep this and all drugs out of the reach of children. The Material Safety Data
Sheet (MSDS) contains more detailed occupational safety information. To report adverse effects in users, to obtain an MSDS, or for assistance call 1-888-6374251. HOW SUPPLIED: Product 55871- Dermatologic Solution TRESADERM Veterinary is supplied in 7.5-ml and 15-ml dropper bottles, each in 12-bottle boxes.
To order, contact your Merial Sales Representative or your Merial Distributor Representative.
-ORCall Merial Customer Care 1-888-Merial-1
1
Kahn CM, Line S. The Merck Veterinary Manual. 9th ed.
Whitehouse Station, NJ: Merck & Co., Inc., 2005.
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