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“…One can think of the middle of the twentieth century as the end of one of the most important social revolutions in history, the virtual elimination of the infectious disease as a significant factor in social life.” Burnet, 1962 IOM Definition of Emerging Infections New, reemerging or drug-resistant infections whose incidence in humans has increased within the past two decades or whose incidence threatens to increase in the near future. 1992 Factors Contributing to the Emergence of Infectious Diseases 1992 2003 Human demographics and behavior Human susceptibility to infection Technology and industry Climate and weather Economic development and land use Changing ecosystems International travel and commerce Microbial adaptation and change Breakdown of public health measures Poverty and social inequality War and famine Lack of political will Intent to harm Institute of Medicine