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QUICKReference Guide Jarrow ® F O R M U L A S healthy living through science & education Jarro-Dophilus EPS ® For Intestinal and Immune Health* Jarro-Dophilus EPS® is a Stable-Dophilus™ due to its stability at room temperature and enteric coating. Eight (8) different strains of probiotic bacteria are delivered directly into small intestines where probiotic bacteria fully exert their beneficial effects.* P R OD U C T CATEGO RY GastroIntestinal Probiotics, Immune Who Can Benefit from this Product? Jarro-Dophilus EPS® can help all adults protect their intestinal tract from putrefactive microorganisms.* What Distinguishes this Product? • A broad spectrum of 8 probiotic species for full intestinal coverage. • Higher potency - 5 billion organisms per capsule. • Stable at room temperature – refrigeration not required. • Enteric coating protects against stomach acid. • Individually blister-sealed capsules afford superior protection. How Does Each Active Ingredient Function in this Product? A unique, high producer of polysaccharides that Lactobacillus facilitate colonization and stimulate intestinal rhamnosus R0011 immune response.* Bifidobacteria longum BB536 (morinaga strain) Lactobacillus acidophilus R0052 Lactococcus and Pediococcus Supplement Facts Serving Size 1 Capsule Amount Per Capsule † Daily Value not established. *Recently reclassified as L. helveticus R0052 Other Ingredients Potato starch, magnesium stearate (vegetable source), and ascorbic acid. Vegetarian capsule consists of hydroxypropylmethylcellulose and an aqueous-based enteric coating. Contains: Soy (less than 0.1%) and milk (casein, less than 0.01%). No wheat, no gluten, no egg, no fish/shellfish, no peanuts/tree nuts. † 5 Billion Organisms guaranteed at time of consumption under recommended storage conditions and within best used by date. Has been shown to colonize, stimulate immune response and promote the growth of beneficial bacteria.* Suggested Usage Assists in breaking down lactose (milk sugar) which may improve digestion of dairy products by those individuals who are lactose intolerant.* Storage Instructions Helps reduce spoilage caused by unfriendly bacteria in cultured dairy products.* ORDERING INFORMATION ORDER CODE: JEP15 ORDER CODE: JEPS ORDER CODE: JEPS120 % DV Probiotic Bacteria Blend (8 Strains) 5 Billion Organisms L. rhamnosus R0011 L. acidophilus R0052* Pediococcus acidilactici R1001 L. casei R0215 L. plantarum R1012 B. longum BB536 Lactococcus lactis ssp. lactis R1058 B. breve R0070 Take 1 to 4 capsules per day, preferably on an empty stomach, though they may also be taken with food, or as directed by your qualified health care consultant. Jarro-Dophilus EPS® is room temperature stable and does not require refrigeration. Refrigerating Jarro-Dophilus EPS™ is optional and will further extend the shelf-life by safeguarding the product from heat, especially during the hot summer months. Blister packaging each capsule provides extra protection to the probiotic bacteria against external moisture and oxygen. SIZE: 15 CAPSULES SIZE: 60 CAPSULES SIZE: 120 CAPSULES *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. For more information visit www.jarrow.com 0610JEPS QUICKReference Guide Jarrow ® F O R M U L A S healthy living through science & education Jarro-Dophilus EPS ® The Ultimate Probiotic The intestines range from a relatively alkaline environment (pH) of the small intestine to an increasingly acidic environment in the large intestine. No one strain of bacteria can provide benefits throughout the entire length of the alimentary canal. This is the reason that Jarrow Formulas® Jarro-Dophilus EPS® supplies eight different strains. In the small intestine (duodenum, jejunum, and ileum), the primary lactic flora which can be supplemented are the lactobacilli, although enterococci are also present. The large intestine exhibits a large proportion of bifidobacteria in addition to its components of lactobacilli and enterococci. The typical intestinal and vaginal flora includes several different species of lactic acid bacteria which perform different activities according to the nature of their enzyme systems. In the case of carbohydrate processing, for example, Lactobacillus rhamnosus ferments at least 24 different carbohydrates: L. acidophilus, up to 16; and L.delbrueckii subsp. bulgaricus, 7 different carbohydrates. This means that the lactic bacteria are important for completing the processing of carbohydrates in the gut. Bifidobacteria, which are located mainly in the large intestine, can ferment a variety of undigested carbohydrates, such as lactulose and oligosaccharides, and produce lactic and acetic acids. This provides the body’s “friendly bacteria” its best protection against unfriendly bacteria and yeast.* Probiotic bacteria are important aids to normal digestion and assimilation beyond the simple processing of carbohydrates.* Some species of lactic acid bacteria contribute to the digestion of proteins, some deconjugate bile salts, some produce specific beneficial bacteriocins, while others enhance the immune response.* The eight different species found in Jarro-Dophilus EPS are representatives of four different genera: lactobacillus, bifidobacteria, lactococcus, and pediococcus. Jarro-Dophilus EPS helps to safeguard and preserve the health of the entire intestinal tract with a mixture of the most important lactobacilli species which include Lactobacillus rhamnosus, L. casei, L. plantarum, and L. acidophilus.* Bifidobacterium longum BB536 (Morinaga strain) has been shown in well-controlled clinical trials to stimulate immune response and to promote the growth of beneficial bacteria.* BB536 also has been shown to reduce the production of IgE, which is related to a healthy histamine response.* R0052 has been shown to support normal bowel functioning, as well as to enhance gastrointestinal health.* Lactobacillus rhamnosus R0011 is a species, which prolifically produces unique polysaccharides which augment intestinal immune response and also facilitate probiotic colonization.* Administration of strains R0052 and R0011 together resulted in more normal bowel responses in children.* Pediococcus helps to minimize putrification in the gut and produces novel pediocins (antibiotic-like bacteriocins).* Requirements for Multi-Species Probiotic Success There are several properties that are required from strains of lactic acid bacteria if these are to result in an efficient probiotic. No single strain can easily fulfill all these requirements. A mixture of species, therefore, is usually most suitable for supplementation. The most desirable properties of a good probiotic are: • Compatibility among the strains • Ability to survive passage through the digestive tract • Stable under normal gastric conditions • Resistance to bile salts • Adherence to intestinal mucosa • Colonization of the human intestinal tract • Safety with regard to human use • Production of natural antimicrobial substances* • Antagonism against unfriendly and putrefactive bacteria* • Stability during storage under normal conditions 5 Billion Organisms Per Capsule At the time of manufacture, Jarro-Dophilus EPS supplies 5 billion live organisms per capsule. Even very hardy species of probiotics must be supplied in sufficient quantities if they are to properly colonize the gut and favorably influence bowel health. Newly advanced processing techniques now permit the production of very concentrated sources of probiotic bacteria, which have been carefully selected for their complimentary interaction with one another. Enteric Coated to Protect Against Stomach Acid The acidity of the stomach forms an important natural barrier against the entry of bacteria and yeasts into the rest of the digestive tract. However, this same barrier can impede probiotic supplementation. Jarro-Dophilus EPS enteric coated capsules bypass the acid barrier and thereby optimize the amount of friendly bacteria to the intestines, giving superior results with fewer capsules. References Available upon request *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. For more information visit www.jarrow.com