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EBCC 10 European Breast Cancer Conference EBCCouncil 9 - 11 MARCH 2016 AMSTERDAM THE NETHERLANDS Isaac Israëls Woman in profile in front of Van Gogh’s sunflowers, 1917 (Oil on canvas – 71 x 59 cm) Museum de Fundatie, Zwolle and Heino/Wijhe, The Netherlands Multidisciplinary Innovation in Breast Cancer Care Be part of a unique gathering of physicians, scientists and patients. Learn to apply the latest findings in a holistic way. ADVANCE PROGRAMME EBCC 10 European Breast Cancer Conference Save the Dates Registration deadlines Early rate registration closes (receipt of payment by) 9 October 2015 Regular rate registration closes (receipt of payment by) 25 January 2016 For group registrations: receipt of complete group participants’ details 25 January 2016 Late rate registration closes Onsite rate registration Accommodation booking closes 11 March 2016 as of 12 March 2016 9 January 2016 Submission deadlines Regular abstract submission opens 15 August 2015 Regular abstract submission closes 4 November 2015 Fellowship grant application closes 4 November 2015 Late-breaking abstract submission opens 15 January 2016 Late-breaking abstract submission closes 22 January 2016 Conference Venue Amsterdam RAI Europaplein 1078 AZ Amsterdam The Netherlands Detailed information about the venue: www.rai.nl ADVANCE PROGRAMME Conference Secretariat 2 c/o ECCO – the European CanCer Organisation Avenue E. Mounier 83 B-1200 Brussels Tel: +32 2 775 02 01 Fax: +32 2 775 02 00 Email: [email protected] Accreditation for Continuous Medical Education (CME) Application for accreditation has been submitted to the Accreditation Council of Oncology in Europe (ACOE). Table of Contents EBCC 10 European Breast Cancer Conference Save the Dates2 Letter of Welcome4 Organising Partners5 Conference Committees7 Programme at a Glance10 Descriptions of Sessions13 Detailed Scientific and Workshop Programme14 Registration34 Call for Abstracts35 Fellowships & Grants36 Call for Nominations37 ADVANCE PROGRAMME General Information38 3 EBCC 10 European Breast Cancer Conference Letter of Welcome The European Breast Cancer Conference in 2016 (EBCC-10) will take place in the context of very tangible advances that have been made for patients in recent years. These advances have been largely achieved through the successful application of a multidisciplinary approach in the treatment and care of breast cancer. EBCC is proud to have played its role in driving these advances for breast cancer patients as a unique, dedicated multidisciplinary platform and the largest breast cancer conference outside the US. This edition of EBCC (EBCC-10) is again firmly based on a holistic vision of breast cancer and brings together scientists, clinicians, patient representatives and health professionals of diverse profiles to tackle key issues facing patients throughout the continuum of the breast cancer journey. The conference programme will provide the latest insights into the areas of prevention, optimal diagnosis, treatment, survivorship, the advance driven by research in all of them so that EBCC again fulfills its mission to accelerate the translation of clinical research into best practice made widely available to patients all over Europe. EBCC-10 will replicate the highly successful “Multidisciplinary Teams in the Real World” and will have a strong focus on the work of the breast team throughout its programme. Our aim is to strengthen the knowledge of different members of the breast team as well as help ensure the optimal work of the team as a whole. The conference registration fee structure has been designed specifically to support the participation of breast teams. The conference will again showcase practice-changing new data and provide delegates with the opportunity to discuss it in sessions with innovative, interactive formats. EBCC-10 will highlight important regulatory developments in Europe. A European Parliament resolution has stipulated that by 2016 member states should have enshrined in law that all breast cancer patients are to be treated in a specialised breast centre or unit. At EBCC-10, we will review the impact this resolution has had so far on the treatment of breast cancer, we will map the status of its implementation and discuss how best to direct our advocacy efforts in 2016 and beyond. ADVANCE PROGRAMME We look forward to welcoming you to Amsterdam on 9 – 11 March 2016: EBCC-10 awaits your active participation. Help us make it our best ever conference! 4 Fatima Cardoso (Portugal) Conference Chair Roswitha Britz (Spain) Conference Co-Chair Emiel Rutgers (Netherlands) National Organising Committee Chair Organising Partners EBCC 10 European Breast Cancer Conference European Breast Cancer Council EBCCouncil The European Breast Cancer Conferences are the responsibility of the not-for-profit association European Breast Cancer Council (EBC Council). The European Breast Cancer Council (EBC Council) is an association of European organisations involved in breast cancer. The three founding members of the organisation are EORTC Breast group, EUSOMA and EUROPA DONNA. The mission of the Association is to raise awareness and improve prevention, diagnosis, treatment and care of breast cancer patients. Founding Members EUROPA DONNA – The European Breast Cancer Coalition is an independent, nonprofit organisation whose members are affiliated groups from throughout Europe. The coalition works to raise awareness of breast cancer and to mobilise the support of European women in pressing for improved breast cancer education, appropriate screening, optimal treatment and care and increased funding for research. EUROPA DONNA represents the interests of European women regarding breast cancer to local and national authorities as well as to institutions of the European Union. The EORTC Breast Cancer Group is a multidisciplinary group of clinical researchers and scientists involved in the development, coordination and implementation of clinical and translational research, endeavouring to improve treatment of breast cancer patients in Europe and beyond. The EORTC BCG has led and/or supported studies that have changed clinical practice in the management of breast cancer, including breast conservation, treatment of DCIS, management of the lymph nodes, neo adjuvant chemotherapy etc.. ADVANCE PROGRAMME For additional information on EUROPA DONNA please visit: www.europadonna.org For additional information on the EORTC Breast Cancer Group please visit: www.eortc.org 5 EBCC 10 European Breast Cancer Conference The European Society of Breast Cancer Specialists (EUSOMA) is a non-profit organisation that promotes the multidisciplinary approach to breast cancer diagnosis and treatment. Its members are specialists from across the spectrum of professions involved in breast care. EUSOMA is committed to promoting interaction between all the health professionals involved in breast cancer care with the aim of ensuring that all patients with breast problems have equitable access to high quality care delivered by specialist breast teams. EUSOMA is directly involved in setting evidence based standards that form the basis for certification and accreditation of breast centres and the clinical care that they provide. ADVANCE PROGRAMME EUSOMA achieves this by organising and participating in workshops and other scientific meetings that consider current evidence that forms the basis for setting standards for early detection, diagnosis, treatment and after care. In these meetings European experts are invited in the different disciplines dedicated to Breast Cancer. These guidelines and recommendations are disseminated throughout Europe. The EUSOMA guidelines ‘The requirements of a specialist breast centre’ are recognised as the current reference document on the definition of breast centres and form the basis for Breast Centre Certification. For additional information on EUSOMA please visit: www.eusoma.org 6 EBCC 10 Conference Committees European Breast Cancer Conference Organising Committee Conference Chair Conference Co-Chair Chair EBCC-9 Chair EBCC-11 Chair National Organising Committee Representatives EBC Council - vzw Representatives EBC Council - vzw F. Cardoso (Portugal) R. Britz (Spain) G. Viale (Italy) R. Mansel (United Kingdom) E. Rutgers (Netherlands) D. Cameron (United Kingdom) E. Bergsten-Nordstrom (Sweden) Scientific Committee Risk Factors M. Schmidt A. Salomon G. Evans B. Borisch Netherlands France United Kingdom Switzerland Step Team Leader Member expert Member expert Member expert Lifestyle/Prevention including Secondary Prevention M. Broeders J. Cuzick A. Young E. Bergsten Nordström Netherlands United Kingdom United Kingdom Sweden Step Team Leader Member expert Member expert Member expert Italy United Kingdom Italy Step Team Leader Member expert Member expert Austria Netherlands Spain Portugal Netherlands Greece Italy Step Team Leader Member expert Member expert Member expert Member expert Member expert Member expert Optimal Diagnosis F. Sardanelli H. Dobson S. Knox M. Knauer P. Poortmans I. Rubio M. Cardoso N. Russell C. Markopoulos A. Moreo ADVANCE PROGRAMME Local Regional Treatment 7 EBCC 10 European Breast Cancer Conference Systemic Treatment N. Harbeck Germany Step Team Leader V. Dieras France Member expert L. Biganzoli Italy Member expert H. Bonnefoi France Member expert S. Loibl Germany Member expert N. Zernik France Member expert Rehabilitation/Survivorship R. Britz Spain Step Team Leader D. Goddard United Kingdom Member expert S. Schagen Netherlands Member expert Y. Wengstrom Sweden Member expert Follow up M. Leidenius M. Arnedos R. Britz Finland France Spain Step Team Leader Member expert Member expert Advanced Disease O. Pagani Switzerland Step Team Leader E. Senkus Poland Member expert H. Wildiers Belgium Member expert E. Brain France Member expert E. Papadopoulos Cyprus Member expert Supportive and Palliative Care including end of life treatment ADVANCE PROGRAMME C. Ripamonti Italy Step Team Leader M. Aapro Switzerland Member expert T. Saarto Finland Member expert S. Kyriakides Cyprus Member expert 8 Basic and Translational research F. Andre P. Dubsky L. van ‘t Veer W. Janni J. Martens F. Penault-Llorca K. Benn France Austria US Germany Netherlands France Italy Step Team Leader Member expert Member expert Member expert Member expert Member expert Member expert EBCC 10 European Breast Cancer Conference National Organising Committee E. Rutgers (Chair) Netherlands Cancer Institute Members Maastricht University Medical Centre / Maastro Clinic Netherlands Cancer Institute Maastricht University Medical Centre University Medical Centre Utrecht Leiden University Medical Center Netherlands Cancer Institute University of California / Netherlands Cancer Institute University Medical Centre Utrecht Netherlands Cancer Institute University Medical Centre Utrecht Pink Ribbon Netherlands BOOG Study Center Europa Donna & Borstkanker Vereniging Nederland KWF Kankerbestrijding Borstkanker Vereniging Nederland ADVANCE PROGRAMME L. Boersma S. Mook M. Schmidt E. van der Wall J. van der Hoeven J. Jonkers L. van ’t Veer R. Pijnappel J. Wesseling N. Wittebolle S. Veenhoff E. van Leeuwen-Stok E. Verschuur M. Rudolphie A. van Staa 9 EBCC 10 European Breast Cancer Conference Programme at a Glance Wednesday 9 March 2016 08:00 Partners in Breast Cancer Workshops European Society of Surgical Oncology 10:00 Senologic European SocieTy International European Oncology for Radiotherapy & Society/International Nursing Society Oncology School of Senology Coffee Break 10:30 12:00 Poster Viewing 12:45 Opening Ceremony including awards 13:30 Special Manifesto Session European Breast Centres 2016: Impact on mortality and 14:40 quality of life 14:45 Plenary Session Keynote Lecture and Tomorrow’s Practice 16:15 Changing Abstracts Coffee Break and Poster Viewing ADVANCE PROGRAMME 16:45 THBT Population How to Communicate Based Mammographic the Diagnosis and Screening Should be Treatment Strategy 17:45 Stopped 17:45 18:45 18:30 20:00 10 Debate Multidisciplinary Team in the Real World Real World Forum Style Your Life Welcome Reception Industry Session: Satellite Symposia European Society of Pathology EBCC 10 European Breast Cancer Conference Thursday 10 March 2016 07:00 Industry Session: Meet the Expert Breakfast Sessions 08:00 08:00 08:30 08:45 Teaching Lecture Teaching Lecture Teaching Lecture Special Issues on the Management of Elderly Breast Cancer Patients Implementation of Oncoplastic Surgery in Clinical Practice Breast Cancer and Pregnancy Teaching Lecture Teaching Lecture Teaching Lecture Bone Health Dignity Therapy Are There New Standards for Adjuvant 09:15 Endocrine Therapy for Young Women? Coffee Break and Poster Viewing 09:45 11:15 11:30 12:30 Clinical Science Symposium Clinical Science Symposium Clinical Science Symposium Controversial Issues With the NeoAdjuvant Approach - including best oral proffered paper(s) Pain Management - including best oral proffered paper(s) Genes and Families - including best oral proffered paper(s) Best Oral Abstracts session Multidisciplinary Team in the Real World Real World Forum To be announced Management of Breast Cancer in the Neoadjuvant Setting European Commission Initiative on Breast Cancer Poster Viewing 12:45 Industry Session: Satellite Symposia 13 :45 15:30 Clinical Science Symposium Clinical Science Symposium Luminal Breast Cancer - including best Local Approaches for Metastases oral proffered paper(s) including best oral proffered paper(s) Coffee Break and Poster Viewing 16:00 Clinical Science Symposium HER 2 Positive Breast Cancer 17:30 including best oral proffered paper(s) 18:30 20:00 Clinical Science Symposium Clinical Science Symposium Controversial Issues in Radiotherapy - Breast Density - How Thick is the Fog? including best oral proffered paper(s) including best oral proffered paper(s) ADVANCE PROGRAMME 14:00 Industry Session: Satellite Symposia 11 EBCC 10 European Breast Cancer Conference Friday 11 March 2016 07:00 Industry Session: Meet the Expert Breakfast Sessions 08:00 08:00 08:30 08:45 09:15 Teaching Lecture Teaching Lecture Real World Forum Time of First Screening, a Life Changing Optimal Pathology for the Diagnosis of Opportunity Breast Cancer Teaching Lecture Teaching Lecture Update on ABC3 Guidelines Different Uses of Breast MRI Survivorship and Social Economic Issues for EBC and ABC Patients 08:00-09:15 Coffee Break and Poster Viewing 09:45 11:15 11:30 12:30 Plenary Session Keynote Lecture and Today’s Practice Changing Abstracts Debate THBT There are too Many Mastectomies Debate Special Session THBT only Breast Tissue Needs Regular Debate on Affordability and Access to Follow Up Cancer Care Poster Viewing 12:45 Industry Session: Satellite Symposia 13 :45 14:00 Clinical Science Symposium Clinical Science Symposium What is new in the Biology of Breast Triple Negative Breast Cancer (TNBC) Cancer? - including best oral proffered including best oral proffered paper(s) paper(s) 15:30 ADVANCE PROGRAMME 15:45 12 16:45 16:30 17:30 Clinical Science Symposium The New Mammography - including best oral proffered paper(s) Multidisciplinary Team in the Real World Real World Forum Advanced Breast Cancer How to Manage Side Effects of Treatment Plenary Session Take Home Messages and Closure Descriptions of Sessions EBCC 10 European Breast Cancer Conference Debates Debates should follow an Oxford style format. A controversial topic is introduced, scientifically challenging a proposer and an opponent to the motion, and opened for debate with the audience. At the end of the session, the audience takes an informal vote. Plenary Session Plenary sessions will include a keynote lecture of an eminent speaker in the field of breast cancer as well as Late Breaking and New Data abstracts. Multidisciplinary Team in the Real world session MTR Panels are interactive and addressing topical subjects comprising a moderator and expert panel representing various disciplines. The Multidisciplinary Team in the real world is an interactive session where a clinical case will be presented followed by an open discussion between the audience and the panel of experts. Clinical Science Symposium A Clinical Science Symposium is focused on a topic/theme followed all the way through; research presentations for instance are to include the latest perspectives of basic, translational and clinical research issues in a specific field. The session provides a forum for presentations followed by high level scientific discussion of the different research areas and best oral abstract(s). Teaching Lectures Teaching Lectures are state-of-the-art lectures and give an overview of the latest developments in the field of breast cancer. This lecture is given by a well-known expert who has the ability to captivate the audience’s attention regarding the future of cancer treatment and care. Special Manifesto Session The manifesto is a statement document prepared by the European Breast Cancer Council working group and launched at the European Breast Cancer Conference in Amsterdam. Partners in Breast Cancer Workshops Societies have been invited to compile Breast Cancer Workshop Programmes related to their field. Real World Forum These are sessions focusing on significant “real world” issues and topics of interest to all participants. Perspectives of patient advocates, scientists, medical professionals, policy and other experts will be presented. ADVANCE PROGRAMME Opening Session The Opening Session will include the European Breast Cancer Science Award (Emmanuel van der Schueren Lecture) and The European Breast Cancer Arts and Humanities Award. 13 EBCC 10 European Breast Cancer Conference Detailed Scientific and Workshop Programme Wednesday 9 March 2016 Updated information is available on the searchable programme – see www.ecco-org.eu/Events/EBCC10 European Society of Surgical Oncology Workshop 08:00 - 12:00 Chair: R.A. Audisio (United Kingdom) LIQUID BIOPSIES AND PRECISION SURGERY Liquid biopsy: Today and tomorrow Speaker: D. Peeters (Belgium) DCIS: Molecular subtypes and individualised prognosis Speaker: W. Zhou (Sweden) Risk adapted breast cancer screening Speaker: L. Esserman (USA) Circulating tumour cells and metastatic breast cancer Speaker: F. Bidard (France) Questions and Answers Coffee break ADVANCED MANAGEMENT OF HER2 3+ TUMOURS Value of tumor-infiltrating lymphocytes in neoadjuvant treatment: Involvement in prognosis and pathologic complete response Speaker: C. Criscitiello (Italy) Guided breast conservative surgery in clinical complete response after neoadjuvant treatments ADVANCE PROGRAMME Speaker: I.T. Rubio (Spain) 14 Fertility preservation Speaker: L. Del Mastro (Italy) How genomic profiling may change the status of HER2 3+ tumours Speaker: L. J. Van ‘t Veer (USA) Questions and Answers EBCC 10 European Breast Cancer Conference European SocieTy for Radiotherapy and Oncology Workshop: Accelerated Partial Breast Irradiation: Current Status and Perspectives 08:00 - 12:00 Chair: B. Offersen (Denmark) Chair: D. Gabrys (Poland) SESSION I Are we treating the disease we think we are? Speaker: D. Gabrys (Poland) GEC-ESTRO consensus guideline for target delineation in partial breast irradiation Speaker: V. Strnad (Germany) TARGIT-A Trial Speaker: F. Wenz (Germany) Results from the ELIOT Trial Speaker: R. Orecchia (Italy) Panel discussion: What are the optimal patient selection criteria for APBI? Can RT be safely withheld in selected patients? Coffee break SESSION II Longterm results of the phase III GEC-ESTRO APBI trial Speaker: C. Polgár (Hungary) Results from the phase III randomised trial IMPORT-LOW Speaker: C.E. Coles (United Kingdom) Results from the randomised DBCG PBI Trial ADVANCE PROGRAMME Speaker: B. Offersen (Denmark) Panel discussion: Is APBI ready for prime time? What is the optimal strategy? What can we learn about volume effects and fractionation? 15 EBCC 10 European Breast Cancer Conference SIS/ISS - Senologic International Society/ International School of Senology: Conceptual Highlights in Benign and Invasive Breast Disease 08:00 - 12:00 Chair: T. Pienkowski (Poland) Chair: R. Orda (Israel) PART I - BENIGN BREAST DISEASE Welcoming remarks Speaker: A. Mundinger (Germany) Which life style columns prevail over breast cancer risk? Speaker: C. Mathelin (France) Modern imaging techniques at the edge — benign vs. malignant? Speaker: A. Mundinger (Germany) Unusual breast disease and the art of cosmetic surgery Speaker: M. Magalhães Costa (Brazil) The international initiative on accrediting breast centres Speaker: R. Orda (Israel) Roundtable discussion Coffee break Chair: A. Mundinger (Germany) Chair: D. Tripathy (USA) PART II - PRE-INVASIVE AND INVASIVE BREAST DISEASE New frontiers of imaging DCIS Speaker: A. Mundinger (Germany) ADVANCE PROGRAMME Highlights in surgical treatment of DCIS Speaker: S. Schneebaum (Israel) Pros and cons on chemoprophylaxis of pre-invasive lesions Speaker: T. Pienkowski (Poland) Translating genetic drivers into new targeted therapies for breast cancer Speaker: D. Tripathy (USA) Closing remarks Speaker: T. Pienkowski (Poland) 16 EBCC 10 European Breast Cancer Conference European Oncology Nursing Society Workshop: The Impact of Breast Cancer on Patients and Caregivers 08:00 - 12:00 Chair: Y. Wengström (Sweden) Chair: N. De Beer (Netherlands) AGE SPECIFIC ITEMS Chemotherapy and pregnancy; the impact on caregivers? Speaker: K. Van Calsteren (Belgium) Intimacy and sexuality during treatment - age specific? Speaker: C. Eeltink (Netherlands) Geriatric assessment - optional or mandatory? Speaker in favour: A. Speelman (Netherlands) Speaker against: E. Brain (France) Discussion with audience Moderator: N. De Beer (Netherlands) Coffee break TRANSITION IN THE PALLIATIVE PHASE Shared decision making during palliative treatment - The do’s and dont’s in a conversation Speaker: M. Baas (Netherlands) How are you handling death? Speaker: B. Buizert (Netherlands) ADVANCE PROGRAMME Question and Answers 17 EBCC 10 European Breast Cancer Conference European Society of Pathology Workshop: Optimal Pathology Characterization of Invasive Breast Cancer 2016 08:00 - 12:00 Chair: T. Tot (Sweden) Chair: A. Sapino (Italy) Introduction: EBCC Glasgow Optimal Pathology Manifesto Speaker: T. Tot (Sweden) Radiological – pathological correlation, a must Speaker: T. Tot (Sweden) The role of tumour typing and grading Speaker: M.P. Foschini (Italy) Problems in determining the tumours’ molecular phenotype Speaker: A. Sapino (Italy) Tumor heterogeneity, a real complication Speaker: G. Pekar (Sweden) Coffee break Diagnosing metastatic disease Speaker: G. Cserni (Hungary) Molecular genetic tools in routine diagnosis Speaker: P.J. Van Diest (Netherlands) Discussion Conclusions Speaker: T. Tot (Sweden) ADVANCE PROGRAMME Poster Viewing 18 12:00-12:45 EBCC 10 European Breast Cancer Conference Opening Ceremony: 10th European Breast Cancer Conference 12:45 - 13:30 WELCOME ADDRESS Conference Chair Chair: F. Cardoso (Portugal) Conference Co-Chair Chair: R. Britz (Spain) National Organising Committee Chair Chair: E.J.T. Rutgers (Netherlands) THE EBCC ARTS AND HUMANITIES AWARD Chair: R. Britz (Spain) The European Breast Cancer Arts and Humanities Award Awardee: To be announced The EBCC Arts and Humanities Award will be presented to the individual who has ‘made a difference’ through an artistic or humanistic activity such as artwork, dance, film, literature, music photography or poetry and whose contribution and personal achievements reflect the efforts and vision that unites EBCC THE EUROPEAN BREAST CANCER SCIENCE AWARD Chair: F. Cardoso (Portugal) Emmanuel van der Schueren Lecture Breast Centres in Europe: Will 2016 be remembered? ADVANCE PROGRAMME Award Lecturer: L. Cataliotti (Italy) 19 EBCC 10 European Breast Cancer Conference Special Manifesto Session: European Breast Centres 2016 - Impact in Mortality and Quality of Life 13:30 - 14:40 Chair: F. Cardoso (Portugal) Chair: E.J.T. Rutgers (Netherlands) The Belgian experience Speaker: F. Liebens (Belgium) The German experience Speaker: S. Wesselmann (Germany) The Dutch experience Speaker: M.J. Vrancken - Peeters (Netherlands) EU Survey - European Breast Centres in 2016: Where are we? Speaker: D. Lerda (Italy) Panel discussion Moderator: F. Cardoso (Portugal) Panel: K. Benn (Italy) E.J.T. Rutgers (Netherlands) D. Lerda (Italy) M.J. Vrancken - Peeters (Netherlands) S. Wesselmann (Germany) F. Liebens (Belgium) A. Costa (Italy) L. Cataliotti (Italy) S. Kyriakides (Cyprus) D.A. Cameron (United Kingdom) Plenary Session: Keynote Lecture and Tomorrow’s Practice Changing Abstracts ADVANCE PROGRAMME 14:45 - 16:15 Chair: To be announced Beyond sequencing the cancer genome Keynote Speaker: R. Bernards (Netherlands) Tomorrow’s practice changing abstracts Poster Viewing 16:15-16:45 20 EBCC 10 European Breast Cancer Conference Debate: This House Believes That Population Based Mammographic Screening Should be Stopped 16:45 - 17:45 Moderator: S. Kyriakides (Cyprus) Speaker in favour: P. Gotzsche (Denmark) Speaker against: M. Untch (Germany) Seconder in favour: P. Zahl (Norway) Seconder against: H. J. De Koning (Netherlands) Discussion & Voting Multidisciplinary Team in the Real World: How to Communicate the Diagnosis and Treatment Strategy 16:45 - 17:45 Moderator: R.E. Mansel (United Kingdom) Case presentation: Speaker: L. Elshof (Netherlands) Panel: Y. Wengström (Sweden) (Nurse) G. Jerusalem (Belgium) (Medical oncologist) D. Razavi (Belgium) (Psycho-oncology) K. Benn (Italy) (Patient advocate) F. Sardanelli (Italy) (Radiologist) Real World Forum: Style Your Life 16:45 - 17:45 Chair: A. Anderson (United Kingdom) Chair: S. Knox (Italy) Speaker: M. Pollan (Spain) Changing lifestyle behaviour for breast cancer prevention Speaker: A. Anderson (United Kingdom) Promoting breast health before and after breast cancer Speaker: S. Knox (Italy) Current evidence on the impact of lifestyle factors on breast cancer Speaker: I. Romieu (France) ADVANCE PROGRAMME Obesity and breast cancer 21 EBCC 10 European Breast Cancer Conference Thursday 10 March 2016 Teaching Lecture: Special Issues on the Management of Elderly Breast Cancer Patients 08:00 - 08:30 Chair: H. Wildiers (Belgium) Speaker: E. Brain (France) Teaching Lecture: Implementation of Oncoplastic Surgery in Clinical Practice 08:00 - 08:30 Chair: B. Carly (Belgium) Speaker: M.J. Cardoso (Portugal) Teaching Lecture: Breast Cancer and Pregnancy 08:00 - 08:45 Chair: F.A. Peccatori (Italy) Speaker: H. Azim jr (Belgium) Teaching Lecture: Are There New Standards for Adjuvant Endocrine Therapy for Young Women? 08:45 - 09:15 Chair: I. Smith (United Kingdom) Speaker: O. Pagani (Switzerland) Teaching Lecture: Bone Health ADVANCE PROGRAMME 08:45 - 09:15 22 Chair: S. Aebi (Switzerland) Speaker: P. Hadji (Germany) Teaching Lecture: Dignity Therapy 08:45 - 09:15 Chair: G. Abela (Malta) Speaker: To be announced EBCC 10 European Breast Cancer Conference Poster Viewing 09:15-09:45 Clinical Science Symposium: Controversial Issues With the Neo-Adjuvant Approach 09:45 - 11:15 Chair: E.J.T. Rutgers (Netherlands) Chair: N. Bese (Turkey) Management of lymph nodes - what to do Speaker: T. Kühn (Germany) Extent of breast surgery Speaker: M. Knauer (Switzerland) Optimal radiological and molecular assessment Speaker: T. Helbich (Austria) Molecular characterisation of residual disease Speaker: E. Provenzano (United Kingdom) Oral proffered paper abstracts Clinical Science Symposium: Pain Management 09:45 - 11:15 Chair: S. Schagen (Netherlands) Chair: D. Fenech (Malta) The assessment of pain Speaker: M. Aapro (Switzerland) Neuropathic pain Speaker: M. Fallon (United Kingdom) Speaker: D. Santini (Italy) Pain due to oncology treatment Speaker: C. Ripamonti (Italy) Oral proffered paper abstracts ADVANCE PROGRAMME Bone pain 23 EBCC 10 European Breast Cancer Conference Clinical Science Symposium: Genes and Families 09:45 - 11:15 Chair: M.K. Schmidt (Netherlands) Chair: B. Borisch (Switzerland) Valid risk predictions and which genes to screen Speaker: D. Easton (United Kingdom) NGS- a solution for all? Speaker: E. Levy-Lahad (Israel) Breast cancer families without hereditary variants- what to do? Speaker: R. Schmutzler (Germany) Consequences for the clinic Speaker: C. Singer (Austria) Oral proffered paper abstracts Multidisciplinary Team in the Real World: Management of Breast Cancer in the Neoadjuvant Setting 11:30 - 12:30 Moderator: S. Delaloge (France) Case presentation Speaker: K. Tryfonidis (Belgium) ADVANCE PROGRAMME Panel: S. Erdem (Turkey) (Patient advocate) A. Di Leo (Italy) (Medical oncologist) A. Costa (Italy) (Surgeon) L. Moser (Portugal) (Radiation oncologist) G. Pruneri (Italy) (Pathologist) 24 EBCC 10 European Breast Cancer Conference Real World Forum: European Commission Initiative on Breast Cancer 11:30 - 12:30 Chair: R. Britz (Spain) Chair: R.E. Mansel (United Kingdom) The Commission’s perspective Speaker: To be announced Guideline development group for EU guidelines revision Speaker: To be announced Quality assurance scheme development group for breast services Speaker: To be announced Patient advocate perspective Speaker: To be announced Poster Viewing 12:30-14:00 Clinical Science Symposium: Luminal Breast Cancer 14:00 - 15:30 Chair: L. Biganzoli (Italy) Chair: B. Sousa (Portugal) Luminal breast cancer, more than two diseases? Speaker: W. Zwart (Netherlands) Find the balance between over and under treatment Speaker: D.A. Cameron (United Kingdom) Endocrine and targeted agents as the new standard of care Speaker: F. André (France) Oral proffered paper abstracts ADVANCE PROGRAMME Speaker: V. Dieras (France) Selection of patients for CDK/mTOR inhibitors? 25 EBCC 10 European Breast Cancer Conference Clinical Science Symposium: Local Approaches for Metastases 14:00 - 15:30 Chair: D. Zardavas (Belgium) Chair: B. Linderholm (Sweden) How to select patients Speaker: E. Senkus (Poland) Brain metastases Speaker: M.J. Van den Bent (Netherlands) Visceral metastases Speaker: K. Gelmon (Canada) Surgery of the primary tumour Speaker: P. Dubsky (Austria) Can we predict and prevent specific sites of metastases? Speaker: R. Gomis (Spain) Oral proffered paper abstracts Poster Viewing 15:30-16:00 Clinical Science Symposium: HER 2 Positive Breast Cancer 16:00 - 17:30 Chair: A. Gennari (Italy) Chair: H. Bonnefoi (France) HER 2 Positive Breast Cancer: still a single disease? ADVANCE PROGRAMME Speaker: N. Harbeck (Germany) Optimal sequencing of anti-HER2-based therapy Speaker: E. Winer (USA) How to overcome resistance to anti-HER-2 agents Speaker: S. Loi (Australia) How women cope with HER-2 Speaker: M. Miklavcic (Slovenia) Oral proffered paper abstracts 26 EBCC 10 European Breast Cancer Conference Clinical Science Symposium: Controversial Issues in Radiotherapy 16:00 - 17:30 Chair: A. Moreo (Italy) Chair: N.S. Russell (Netherlands) When are lymph nodes a target? Speaker: P. Poortmans (Netherlands) Timing of radiotherapy and reconstruction Speaker: L. Moser (Portugal) Is radiotherapy for all DCIS? Speaker: B. Chua (Australia) Is biological-driven radiotherapy possible? Speaker: L. Pierce (USA) Oral proffered paper abstracts Clinical Science Symposium: Breast Density - How Thick is the Fog? 16:00 - 17:30 Chair: D. Goddard (United Kingdom) Chair: M. Christiaens (Belgium) What women should or should not know about breast density Speaker: E. Bergsten-Nordstrom (Sweden) How to measure breast density Speaker: A. Tagliafico (Italy) Breast density as a masking factor Speaker: U. Bick (Germany) Speaker: C. Colin (France) Tamoxifen for breast density Speaker: L. J. Van ‘t Veer (USA) Oral proffered paper abstracts ADVANCE PROGRAMME Breast density as a questionable prognostic factor 27 EBCC 10 European Breast Cancer Conference Friday 11 March 2016 Teaching Lecture: Time of First Screening, a Life Changing Opportunity 08:00 - 08:30 Chair: M. Broeders (Netherlands) Speaker: P. Hall (Sweden) Teaching Lecture: Optimal Pathology for the Diagnosis of Breast Cancer 08:00 - 08:30 Chair: M. Fernö (Sweden) Speaker:G. Viale (Italy) Real World Forum: Survivorship and Social Economic Issues for EBC and ABC Patients 08:00 - 09:15 Chair: L.D. Shockney (USA) Chair: N. Zernik (France) Back to work Speaker: I. Lebrocquy (Netherlands) Breast cancer survivors-uninsurable Speaker: E. Bergsten-Nordstrom (Sweden) Daily life support Speaker: L.D. Shockney (USA) Psycho-social support: What’s new? ADVANCE PROGRAMME Speaker: L. Fallowfield (United Kingdom) 28 A patient experience: How to navigate in stormy waters Speaker: E. Papadopoulos (Cyprus) Teaching Lecture: Update on ABC3 Guidelines 08:45 - 09:15 Chair: S. Paluch-Shimon (Israel) Speaker: F. Cardoso (Portugal) EBCC 10 European Breast Cancer Conference Teaching Lecture: Different Uses of Breast MRI 08:45 - 09:15 Chair: E. Verschuur-van der Voort (Netherlands) Speaker: F. Sardanelli (Italy) Poster Viewing 09:15-09:45 Plenary Session: Keynote Lecture and Today’s Practice Changing Abstracts 09:45 - 11:15 Chairs: To be announced To be announced Keynote Speaker: to be announced Today’s practice changing abstracts Debate: This House Believes that There are Too Many Mastectomies 11:30 - 12:30 Moderator: D.A. Cameron (United Kingdom) Speaker in favour: M.J. Cardoso (Portugal) Speaker against: M. Gnant (Austria) Seconder in favour: I.T. Rubio (Spain) Seconder against: M. Rezai (Germany) Debate: This House Believes that Only Breast Tissue Needs Regular Follow Up 11:30 - 12:30 Moderator: M. Aapro (Switzerland) Speaker in favour: M. Leidenius (Finland) Seconder in favour: F. Gilbert (United Kingdom) Speaker against: J. Bergh (Sweden) Seconder against: E. Bergsten-Nordstrom (Sweden) ADVANCE PROGRAMME Discussion & Voting Discussion & Voting 29 EBCC 10 European Breast Cancer Conference Special Session: Debate on Affordability and Access to Cancer Care 11:30 - 12:30 Chair: F. Cardoso (Portugal) Affording Effective Prevention, Treatment and Care – Breast Cancer in the 21st Century Speaker: D.G. Taylor (United Kingdom) Panel discussion Moderator: F. Cardoso (Portugal) N. Harbeck (Germany) (Gynaecologist) C. Jommi (Italy) (Policy analysis and public management) S. Kyriakides (Cyprus) (Patient advocate) To be announced (Health care) A. Eniu (Romania) (Medical oncologist) C. Markopoulos (Greece) (Medical oncologist) N. El Saghir (Lebanon) (Medical oncologist) To be announced (Pharma) Poster Viewing 12:30-14:00 Clinical Science Symposium: Triple Negative Breast Cancer (TNBC) 14:00 - 15:30 Chair: M. Piccart (Belgium) Chair: C. Drukker (Netherlands) Triple negative breast cancer: Still an entity in 2016? ADVANCE PROGRAMME Speaker: C. Caldas (United Kingdom) 30 Time to change the standard? Speaker: S. Loibl (Germany) Metastatic TNBC: Anything beyond chemotherapy? Speaker: A. Tutt (United Kingdom) Oral proffered paper abstracts EBCC 10 European Breast Cancer Conference Clinical Science Symposium: What is New in the Biology of Breast Cancer? 14:00 - 15:30 Chair: F. Penault-Llorca (France) Chair: J.W. Martens (Netherlands) Technical approach: Biopsies vs CTC vs circulating nucleic acids Speaker: W. Janni (Germany) Genomic landscape of metastatic breast cancer Speaker: M. Arnedos (France) Is it possible to identify genetic determinants of lethal breast cancers? Speaker: D. Cox (France) Stem cells: Stem cell targeting Speaker: R. Clarkson (United Kingdom) Oral proffered paper abstracts Clinical Science Symposium: The New Mammography 14:00 - 15:30 Chair: F. Sardanelli (Italy) Chair: E. Tomberg (Estonia) Tomosynthesis for screening Speaker: P. Skaane (Norway) Tomosynthesis for diagnosis Speaker: R. Pijnappel (Netherlands) Contrast enhanced mammography Speaker: E. Fallenberg (Germany) Speaker: M. Wallis (United Kingdom) Oral proffered paper abstracts ADVANCE PROGRAMME Photon counting 31 EBCC 10 European Breast Cancer Conference Multidisciplinary Team in the Real World: Advanced Breast Cancer 15:45 - 16:45 Moderator: A. Eniu (Romania) Case presentation Speaker: J. Ribeiro (Portugal) Panel: H. Wildiers (Belgium) (Medical oncologist) C. Vrieling (Switzerland) (Radiation oncologist) E. Papadopoulos (Cyprus) (Patient advocate) R. Rouzier (France) (Surgeon) N. West (United Kingdom) (Nurse) T. Saarto (Finland) (Medical oncologist) Real World Forum: How to Manage Side Effects of Treatment 15:45 - 16:45 Chair: M. Miklavcic (Slovenia) Chair: M. Ignatiadis (Belgium) Use of complementary medicine Speaker: D. Barton (USA) Use of exercise Speaker: O. Gentilini (Italy) Cognitive function Speaker: S. Schagen (Netherlands) Fatigue Speaker: F. Roila (Italy) ADVANCE PROGRAMME Depression 32 Speaker: S. Higgins (Ireland) Questions and Answers EBCC 10 European Breast Cancer Conference Plenary Session: Take Home Messages and Closure 16:30 - 17:30 Chair: F. Cardoso (Portugal) Chair: R. Britz (Spain) Chair: E.J.T. Rutgers (Netherlands) Take home messages for early breast cancer Speaker: A. Di Leo (Italy) Take home messages for advanced breast cancer Speaker: K. Gelmon (Canada) The patient advocate perspective Speaker: R. Britz (Spain) Closure ADVANCE PROGRAMME Speaker: F. Cardoso (Portugal) 33 EBCC 10 European Breast Cancer Conference Registration Register online at: www.ecco-org.eu/EBCC10 Registration Fees Register early to attend EBCC10 - The European Breast Cancer Conference - and benefit from significant savings of fees. It is our priority to make the Conference accessible to all groups who contribute their perspectives to the impressive progress in breast cancer treatment and care. Our rates are designed to facilitate the attendance of diverse professionals, patient advocates and students. Special registration incentive for Breast Cancer Teams: 1 free registration is offered upon registration of 3 (three) participants with different professional profiles from the same work place. Early Rate – deadline: 9 October 2015 Physicians (Surgical Oncologists, Medical Oncologists, Radiation Oncologists, Gynaecologists, Pathologists, Imaging specialists, Geneticists, GPs) €505 Industry (Public affairs, regulatory, medical affairs) €505 Care givers (clinical, community, hospital & oncology pharmacists, nurses, palliative care specialists, rehabilitation specialists, psychologists) €250 Researchers (Epidemiologists, Scientists, Data managers, Biostatisticians) €250 Emerging Economy*** €150 Patient Advocates* €125 Students** €125 ADVANCE PROGRAMME Regular Rate – deadline: 25 January 2016 34 Physicians (Surgical Oncologists, Medical Oncologists, Radiation Oncologists, Gynaecologists, Pathologists, Imaging specialists, Geneticists, GPs) €745 Industry (Public affairs, regulatory, medical affairs) €745 Care givers (clinical, community, hospital & oncology pharmacists, nurses, palliative care specialists, rehabilitation specialists, psychologists) €510 Researchers (Epidemiologists, Scientists, Data managers, Biostatisticians) €510 Patient Advocates* €175 Students** €175 Late Rate – as of 26 January 2016 Physicians (Surgical Oncologists, Medical Oncologists, Radiation Oncologists, Gynaecologists, Pathologists, Imaging specialists, Geneticists, GPs) €875 Industry (Public affairs, regulatory, medical affairs) €875 Care givers (clinical, community, hospital & oncology pharmacists, nurses, palliative care specialists, rehabilitation specialists, psychologists) €650 Researchers (Epidemiologists, Scientists, Data managers, Biostatisticians) €650 Patient Advocates* €300 Students** €300 EBCC 10 European Breast Cancer Conference Optional Social Event*** €65. The day registration rate of €350 per person will open at the venue only, as of 8 March 2016. * The patient advocate rate applies exclusively for individuals who are a member of Patient Advocacy Organisation. ** Confirmation in ‘training’ status from the Head of Department is required. *** Emerging Economy rate applies to individuals from low and lower-middle-income economies according to the World Bank listing. http://data.worldbank.org/about/country-and-lending-groups **** This ticket gives access to the social event held on Thursday 10 March 2016. Call for Abstracts EBCC is instrumental in driving advances for breast cancer patients as a unique, dedicated multidisciplinary platform and the largest breast cancer conference outside the US. It traditionally attracts ground-breaking, practice-changing data and it has a global outreach through the number of journalists attending the meeting. • Abstracts submitted after the stipulated deadline will not be considered. • Authors are strongly advised to submit prior to the deadline and avoid unnecessary delays which may affect the standing of their abstract. • For more information on abstract topics, format, submission and selection process, please visit the Congress website: www.ecco-org.eu/EBCC10 Regular Abstracts Abstract submission open: Abstract submission deadline: 15 August 2015 4 November 2015, 21:00 Central European Time Late-Breaking Abstracts Abstract submission open: Abstract submission deadline: 15 January 2016 22 January 2016, 21:00 Central European Time Please note that the late-breaking abstract deadline is not an extension of the regular abstract submission deadline. ADVANCE PROGRAMME The presenting author will receive confirmation of acceptance or rejection by mid December 2015 The presenting author will receive confirmation of acceptance or rejection by the beginning of February 2016. 35 EBCC 10 European Breast Cancer Conference Fellowships & Grants Europa Donna Fellowship Grants The Organising Committee will award five Europa Donna fellowships to breast cancer advocates. To be considered for a Europa Donna Fellowship the following criteria should apply: 1. 2. 3. 4. breast cancer survivor under the age of 40 years fluent in English demonstrated some involvement in breast cancer advocacy work for at least one year To apply: The individual must provide a short abstract (400 words) about your current advocacy activities and indicate why EBCC-10 will be important to your future advocacy work. This paper should be submitted to the Head Office of EUROPA DONNA for the Board to review. Each fellowship grant shall be worth a free registration, free accommodation for a maximum of 3 nights and reimbursement of travel costs up to a maximum of 500 EUR (reimbursement after the conference). Applicants who meet the above criteria should send their abstracts to: EUROPA DONNA - The European Breast Cancer Coalition Piazza Amendola 3 20149 Milan, Italy Tel: +39 02 3659 2280 Fax: +39 02 3659 2284 [email protected] Deadline for receipt of applications is 14 September 2015 ADVANCE PROGRAMME The applications will be reviewed by the Europa Donna Board and EBCC-10 Scientific Executive Committee. Successful applicants will be notified in January 2016. 36 EBCC 10 Call for Nominations European Breast Cancer Conference The European Breast Cancer Arts and Humanities Award The Organising Committee of the 10th European Breast Cancer Conference invites nominations for the EBCC Arts and Humanities Award, a prize that recognizes an outstanding contribution to the arts/humanities and which has a direct relationship to the fight against breast cancer. The EBCC Arts and Humanities Award will be awarded to the individual who has “made a difference” through an artistic or humanistic activity such as: artwork, dance, film, literature, music, photography or poetry and whose contribution and personal achievements reflect the efforts and vision that unites EBCC. It is important that such efforts do not go unrecognized, thus we invite you to look within your respective countries and nominate an individual whom you believe deserves this significant recognition on the occasion of the 10th European Breast Cancer Conference in Amsterdam. The EBCC Arts and Humanities Award is worth 1,500 EUR and includes an allexpenses- paid trip to attend EBCC-10. Please submit your nomination directly to: EUROPA DONNA- The European Breast Cancer Coalition Piazza Amendola, 3 20149 Milan- Italy tel. +39 02 3659 2280 fax. +39 02 3659 2284 [email protected] Nominations must be received by 1 December 2015 EBCC-10 Fellowship Grants Fellowship submission open: Fellowship submission deadline: 15 August 2015 4 November 2015, 21:00 Central European Time For submission of your fellowship application please go to: www.ecco-org.eu/EBCC10 The Organising Committee will award a number of fellowship grants to young doctors, basic scientists, nurses and others involved in breast cancer care and advocacy, from developing countries to attend the European Breast Cancer Conference in Amsterdam. (Applied to individuals from low-income and lowermiddle-income economies according to the World Bank listing available at: http:// data.worldbank.org/about/country-classifications/country-and-lending-groups) Fellowship for individuals from limited resources countries The Organising Committee will award a number of fellowship grants to young doctors, basic scientists, nurses and others involved in breast cancer care and advocacy, from countries with limited resources to attend the European Breast Cancer Conference in Amsterdam. ADVANCE PROGRAMME Fellowship for individuals from developing countries 37 EBCC 10 European Breast Cancer Conference General Information Accommodation Amsterdam RAI Hotel & Travel Service has been appointed as the official local housing partner for EBCC-10 and is offering hotel accommodation for both groups and individuals. For all accommodation queries and information, please visit: www.rai.nl/hotelservice For questions, please contact: [email protected] or tel: +31 (0)20 549 1927. We kindly ask you to contact the appointed local housing partner directly. The Conference secretariat cannot provide accommodation-related information or handle any such related requests. Accommodation reservation deadline: 9 January 2016 Exhibition & Sponsorship The recognised multidisciplinary setting of EBCC-10 will once again provide ideal surroundings for participants to leverage knowledge, promote education and build awareness about breast cancer – placing the patient at the heart of all our efforts and discussions. The Conference strives to further the role of multidisciplinary oncology in breast cancer by encouraging participation and interaction between all oncology professions. For information on sponsorship and exhibition opportunities, please contact: Bruno De Man, tel: +32 2 775 02 04, email: [email protected]. The Invitation to Industry brochure and exhibition floor plan will be published on the Conference website: http://www.ecco-org.eu/Events/EBCC10. Insurance The organisers do not accept liability for individual medical, travel or personal insurance. Participants are strongly encouraged to make their own arrangements regarding health and travel insurance. ADVANCE PROGRAMME Language and Translation The official language of the Conference is English. No simultaneous translation will be provided. Lunch and Refreshments Coffee breaks courtesy of the organisers will be scheduled during the Conference. Delegates are invited to buy their own luncheons from the cash-bars located throughout the Conference centre. Please note that only payment in euro is accepted. Free water dispensers are available throughout the Conference centre. 38 EBCC 10 European Breast Cancer Conference EBCC Networking Evening A Unique Venue for a Warm and Friendly Networking Evening This evening is organised for Conference delegates as an opportunity for even more memorable interactions among peers from different areas in oncology. It will take place at the National Maritime Museum. Completely renovated, the Museum exudes history in its impressive, refreshed glory. During the EBCC networking evening, the Museum will be the centre of lively exchange among Conference delegates in a warm atmosphere of memorable hospitality. Tickets will be available for purchase at the time of registration for the Conference. Availability of tickets on site may be limited so purchase at registration is highly recommended. The Bulletin The Bulletin is the official e-newsletter of EBCC-10. Designed specifically to help keep you fully informed about the latest scientific programme highlights and exciting developments in the lead up to the Conference. Launching six months in advance of the Conference, this monthly newsletter is sent to all registrants and appears on the Conference website: www.ecco-org.eu/EBCC10. If you wish to subscribe, please visit www.ecco-org.eu and create an account. Participants registered for the entire duration of the EBCC-10 Conference are entitled to one free public transport ticket giving access to public transport in Amsterdam throughout the event (transportation to and from the airport is not included). Delegates are encouraged to use public transport as much as possible. ADVANCE PROGRAMME Transportation 39 EBCC 10 European Breast Cancer Conference EBCCouncil 9 - 11 MARCH 2016 AMSTERDAM THE NETHERLANDS Conference Secretariat: c/o ECCO – the European CanCer Organisation Avenue E. Mounier, 83 B-1200 Brussels Belgium Tel.: +32 (0) 2 775 02 01 Fax: + 32 (0) 2 775 02 00 [email protected] www.ecco-org.eu/EBCC