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Department of Pediatric Hematology and Oncology
2nd Faculty of Medicine, Charles University Prague
POSTGRADUATE POSITION AVAILABLE
Childhood Leukemia Investigation Prague working group is looking for a
PhD student. The candidate is expected to possess experience in
molecular and cellular biology, as well as motivation, work ethics,
independence, intellectual initiative and dedication. The project is focused
on the metabolic program of leukemic cells. Cancer metabolism is a highly
current topic and it is hard to overstress its importance for the
understanding of variable sensitivity of patient blasts to therapy, drug
efficiency and development of resistance. The main substance - the
metabolic effects of which have been subject to our research for quite
some time - is the L-asparaginase, a crucial component of the childhood
ALL treatment protocol. Currently, it is being introduced into the
treatment of adults as well. Our project utilizes in vitro and in vivo
models, genetic engineering, the newest detection methods in
metabolomics or measurement of metabolic pathways. The project is
pursued in close cooperation with the Academy of Sciences of the Czech
Republic as well as with researchers abroad. Deadline for application is
30th of April 2016.
Contact:
Julia Starkova, PhD., Principal Investigator
Email: [email protected]