Download etanercept level elisa m1887

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Transcript
ETANERCEPT LEVEL ELISA
M1887
Your solution for fast, reproducible and
specific quantification of Etanercept
concentrations in plasma and serum.
Kit content
•
Principle of the test:
Coating antibody, recombinant TNF, biotinylated antibody,
streptavidin-poly-HRP conjugate, HPE-dilution buffer
•
Reagents for four 96-wells plates (384 tests)
•
Comprehensive protocol
Key features
•
Highly specific for Etanercept
•
Assay range optimised to clinically relevant concentrations
•
Basic ELISA for easy implementation in your laboratory
•
Research Use Only
Wells of a 96 microtiter
plate are coated with an
anti-TNF capture
antibody.
Recombinant TNF is
added to each well and
binds to the anti-TNF
capture antibody.
Why monitor for Etanercept?
Etanercept is a tumour necrosis factor (TNF) inhibitor that is
frequently administered to patients who suffer from
diseases where inflammation is an important cause of the
clinical symptoms, such as rheumatoid arthritis. Inhibition of
the inflammation can increase the quality of life of a
patient. Studying Etanercept drug levels in relation to
Patient serum/plasma or
the calibration curve is
added to the well. The
Etanercept present in
the samples will bind to
TNF.
clinical response may help to determine the most suitable
dose of Etanercept. This knowledge may lead to an optimal
Biotinylated antibody
directed to the idiotype
of Etanercept is added
to each well.
treatment schedule for Etanercept and may result in patient
adjusted treatments.
Sanquin Blood Supply, division Reagents
Internationally active scientists from Sanquin are involved in
various global (clinical) research studies in the field of TNF
inhibitors. This expertise, in combination with the longstanding experience in assay development of the division
Streptavidin-HRP is
added to each well,
followed by a colour
reaction.
Reagents, resulted in a high quality Etanercept level ELISA.
Sanquin Blood Supply
Division Reagents
Telephone +31 20 512 35 99
Fax +31 20 512 35 70
E-mail [email protected]
www.sanquinreagents.com