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FACULTY OF PHARMACY Course Specifications: (CHEM 103) Month, Year: Fall 2008 A- Basic Information Programme(s) on which the course is given Bachelor of Pharmaceutical Sciences and Drug Manufacture. Major or minor element of programmes Department offering the course Department of Organic Chemistry Department teaching the course Department of Organic Chemistry Academic year / Level First year / second semester Course title and code Chem. 103 (Basic Org. Chem.) Contact hours (credit hours) Lecture:2 Practical: 2(1) Total: 4(2+1) Dr Abd-Allah Shaaban El-Etrawy Course coordinator B- Professional Information 1 – Overall Aims of Course: The course is concerned with study of the fundamental principles of chemistry of aliphatic compounds. Laboratory work: The laboratory work involves identification of aliphatic compounds. 2. Intended Learning Outcomes of Course (ILOs) i- Knowledge and Understanding: By the end of this course the student should know and understand the theoretical basis of: Organic chemistry and the type organic chemical reactions involved. Methods of identification of aliphatic compounds. ii- Intellectual Skills By the end of this course the student should be able to; Write the structure and name of organic compounds. Draw the possible isomer. The students are able to understanding the reaction mechanisms and effect of condition on the type of products . iii- Professional and Practical Skills By the end of this course the student should be able • Apply the given knowledge to identification the nature of aliphatic compound • Design certain schemes for the identification of different classes of aliphatic compounds. iv- General and Transferable Skills By the end of this course the student should be able to solve given problems concerning the topics of the course in a systematic way. 3. Contents 1 st week 2 nd Week 3 rd week 4th Week 5th Week 6th Week 7th Week Lecture topic Practical and tutorials topic 2 hours/ week = 26 hours 2 hours/ week = 26 hours Introduction, type of chemical bonds, Introduction & safety. hybridization and their types. Representation of organic compounds, type Physical Character. of isomerism, electronic effects (inductive Condition, Colour, Odour & & resonance), and Steric effect Solubility. Type of organic reactions, and type of their Chemical Character. mechanisms, formal charge, and Soda lime, NaOH, FeCl3 & classification of organic compounds Conc. H2SO4 Saturated hydrocarbons (nomenclature, Alcohols. preparations, and properties), and free Methanol, Ethanol & Glycerol. radical substitution reaction mechanism. Alkenes and cycloalkenes (nomenclature, Aldehydes & Ketones. preparations, and properties), and Acetaldehyde, Formaldehyde & elimination & addition reaction mechanism Acetone Alkynes (nomenclature, preparations, and Carboxylic Acids. properties), acidity of acetylene Formic acid, Acetic acid. Alkyl halides (nomenclature, preparations, Carboxylic Acids. and properties), Nucleophilic substitution Oxalic acid, Tartaric acid & reactions mechanism, and reactions of Citric acid. organometallic compounds. Mid-term exam 8th Week 9th Week 10th Alcohols (nomenclature, preparations, and Week properties), esterification reaction mechanisms – Ethers (nomenclature, preparations, and properties) th 11 Aliphatic aldehydes & Ketones Week (nomenclature, preparations, and properties), Addition, condensation (Aldol) reaction mechanism, and cannizaro reaction th 12 Aliphatic carboxylic acids (nomenclature, Week preparations, and properties), factors affecting on the acidity of acids Salts of Carboxylic Acids. (Amm., K+, Na+…..). Urea & Revision. General Scheme for Liquid Unknown 13th Derivatives of aliphatic of carboxylic acidsWeek amides, anhydrides, esters, acid halides, nitriles (nomenclature, preparations, and properties). 14th Aliphatic amines (nomenclature, week preparations, and properties) 15th Carbamide & Revision week General Scheme for Solid Unknown. Final Exam. Final Exam. 4. Teaching and Learning Methods 4.1-Lectures 4.2-Pactical sessions 5. Student Assessment Methods 5.1 practical examinations to assess practical and professional skills of the students 5.2 written exam to assess knowledge, comprehension and other intellectual skills. Assessment Schedule Assessment 1… quiz Week 4th Assessment 2 … midterm Week 8th Assessment 3… quiz Week 12th Assessment 4… final. Week 15th Weighing of Assessments Mid-Term Examination 20 % Final-term Examination 33.3% Practical Examination 33.3% Semester Work 13.33% Other types of assessment 0 % Total 100% 150 marks 6. List of References 6.1- Course Notes Lecture notes on Basic organic Chemistry CHEM 103 by Prof. Dr. Khadiga Mohamed Attia and Dr. Abd-Allah Shaaban El-Etrawy 6.2- Recommended Books Essential organic chemistry, Paula Yurkanis Bruice, (2006), Organic Chemistry, structure & reactivity, Seyhan Ege (2005), Advanced Organic Chemistry; March's, and qualitative organic analysis Vogel's 7. Facilities Required for Teaching and Learning Boards, overhead projector, and data show power points. Laboratories equipped by, chemicals and glasswares Course Coordinator: Dr/ Abd-Allah Shaaban El-Etrawy Course Coordinator: Prof.El-Zeiny Ebeid Date: January 2008