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Transcript
Review Questions on Basic Pharmacology. Make a list of your answers & then check them against the Answer Key 1. An antagonist is a type of drug that: A.has maximal efficacy B.has affinity for a receptor but little efficacy C.binds to a receptor and activates it D.has efficacy but low affinity E.decreases the concentration of an agonist required to produce an effect _____________________________ 2. A partial agonist in Figure 1: A.Drug A B.Drug B C.Drug C D.Drug D (assuming that Drug D does not produce a measurable response) E.None of the above Figure 1: 3. Drug with the highest potency in Figure 1: A.Drug A B.Drug B C.Drug C D.Drug D E.None of the above 1 _____________________________________ Figure 2: 4. Drug with highest efficacy in Figure 2: A.Drug A B.Drug B C.Drug C D.Drug D E.None of the above 5. Drug with the greatest potency in Figure 2: A.Drug A B.Drug B C.Drug C D.Drug D E.None of the above 6. An agonist is a type of drug that: A.binds to a receptor without activating it B.prevents the metabolism of other drugs C.competes noncompetitively with antagonists D.binds to a receptor and activates it E.stimulates the metabolism of other drugs 2 ___________________________________________ Figure 3: 7. In Figure 3, the point or characteristic of the dose response curve that is used to define drug potency is: A.Point A B.Point B (slope) C.Point C D.Point D E.None of the above 8. In Figure 3, the point or characteristic of the dose response curve that is used to define drug efficacy is: A.Point A B.Point B (slope) C.Point C D.Point D E.None of the above 9. Drug affinity for a receptor is most closely associated with a drugs: A.potency B.efficacy C.selectivity D.toxicity E.safety 3