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Annexure ‘CD – 01’ Course Title : BIOINORGANIC AND ORGANOMETALLIC CHEMISTRY Course Code: CHEM 612 L T S SW/ FW P Course Objectives: 3 0 - - 0 TOTAL CREDIT UNITS 3 The proposed course work is an interdisciplinary paper which is optional for students, floated as per the interest area of students. The different aspects of chemistry can be well understood by going through the detailed contents of this course. This lecture based course will cover the various aspects of pure and applied chemistry. Pre-requisites: Proper knowledge of basics of bio - inorganic chemistry taught at elementary level as well as complexes with metals. Spectroscopy will be introduced to the students from the basic level. Course Contents/Syllabus: Weightage (%) Module I: Metals in biology 25% Descriptors/Topics Transport acrossmembranes The sodium-potassium ATPase Biological functions of iron-containing proteins Cobalamine and cobalt proteins The brain and blood barrier Module II: Non-metals in biology Descriptors/Topics The major biogeochemical cycles: carbon, hydrogen, oxygen, 15% The nitrogen cycle, sulfur, chlorine, iodine Module III: Organometallic Chemistry Descriptors/Topics 25% Introduction, definition and scope of organometallic Chemistry, valence electron count, 18 and 16 electron complexes, d-block carbonyls, coordination modes, characterization, synthesis, reactions, carbonyl metallates, ligands related to CO, Synthesis, bonding, Properties and applications of carbenes, carbynes 20% Module IV: Clusters, Polyenes and Macrocycles: Descriptors/Topics Metal-Metal Bonds and Transition Metal atom clusters, carbocyclic polyenes: Synthesis, bonding, Properties and applications, Transition Metal organometallic intermediates in organic synthesis. Organometallic compounds with biological and environmental relevance. 15% Module V: Applicatications of organometallics Descriptors/Topics Applications of various organometallic compounds in fields of medicine and other industrial applicatipons. Student Learning Outcomes: 1. The student will be able to demonstrate the knowledge of some biologically important molecules 2. To explain their mechanistic pathways and to apply their potential applications in various aspects of life and bioinorganic chemistry. Pedagogy for Course Delivery: The course pedagogy will include lecture delivery as well as discussion of relevant and recent research papers. Assignments and tests will also be given for continuous assessment. (a) Lab/ Practicals: NA List of Experiments Assessment/ Examination Scheme: Theory L/T (%) 100% Lab/Practical/Studio (%) nil Theory Assessment (L&T): Continuous Assessment/Internal Assessment Components (Drop down) End Term Examination CT Home Assignment Viva Attendance 10 7 8 5 Weightage (%): 100 70 Text & References: Advanced Practical Physical Chemistry, J.B. Yadav, Goel Publishing House,Meerut. A Textbook of quantitative inorganic analysis including elementary instrumental analysis, IVth Edition Vogel, ELBS and Longman Publication Advanced Practical Inorganic Chemistry, Gurdeep Raj, Goel Publishing House,Meerut. Advanced Practical Organic Chemistry, O.P. Agarwal, Krishna Prakashan Meerut Advanced Physical Chemistry Experiment, Gurtu and Gurtu, Pragati prakashan, Meerut. A Textbook of quantitative chemical analysis, VIth Edition Vogel, Pearson Education Limited.