Download Module I: Metals in biology

Annexure ‘CD – 01’
Course Title : BIOINORGANIC AND ORGANOMETALLIC CHEMISTRY
Course Code: CHEM 612
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Course Objectives:
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TOTAL
CREDIT
UNITS
3
The proposed course work is an interdisciplinary paper which is optional for students, floated as per the interest area of students. The different aspects of chemistry can be
well understood by going through the detailed contents of this course. This lecture based course will cover the various aspects of pure and applied chemistry.
Pre-requisites:
Proper knowledge of basics of bio - inorganic chemistry taught at elementary level as well as complexes with metals. Spectroscopy will be introduced to the
students from the basic level.
Course Contents/Syllabus:
Weightage (%)
Module I: Metals in biology
25%
Descriptors/Topics
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Transport acrossmembranes
The sodium-potassium ATPase
Biological functions of iron-containing proteins
Cobalamine and cobalt proteins
The brain and blood barrier
Module II: Non-metals in biology
Descriptors/Topics
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The major biogeochemical cycles: carbon, hydrogen, oxygen,
15%
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The nitrogen cycle, sulfur, chlorine, iodine
Module III: Organometallic Chemistry
Descriptors/Topics
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25%
Introduction, definition and scope of organometallic Chemistry, valence electron count, 18 and 16 electron
complexes,
d-block carbonyls, coordination modes,
characterization, synthesis, reactions, carbonyl metallates, ligands related to CO,
Synthesis, bonding, Properties and applications of carbenes, carbynes
20%
Module IV: Clusters, Polyenes and Macrocycles:
Descriptors/Topics
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Metal-Metal Bonds and Transition Metal atom clusters,
carbocyclic polyenes: Synthesis, bonding, Properties and applications,
Transition Metal organometallic intermediates in organic synthesis.
Organometallic compounds with biological and environmental relevance.
15%
Module V: Applicatications of organometallics
Descriptors/Topics
 Applications of various organometallic
compounds in fields of medicine and other industrial applicatipons.
Student Learning Outcomes:
1. The student will be able to demonstrate the knowledge of some biologically important molecules
2. To explain their mechanistic pathways and to apply their potential applications in various aspects of life and bioinorganic chemistry.
Pedagogy for Course Delivery:
The course pedagogy will include lecture delivery as well as discussion of relevant and recent research papers. Assignments and tests will also be given
for continuous assessment.
(a) Lab/ Practicals: NA
List of Experiments
Assessment/ Examination Scheme:
Theory L/T (%)
100%
Lab/Practical/Studio
(%)
nil
Theory Assessment (L&T):
Continuous Assessment/Internal Assessment
Components (Drop
down)
End Term Examination
CT
Home Assignment
Viva
Attendance
10
7
8
5
Weightage (%): 100
70
Text & References:
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Advanced Practical Physical Chemistry, J.B. Yadav, Goel Publishing House,Meerut.
A Textbook of quantitative inorganic analysis including elementary instrumental analysis, IVth Edition Vogel, ELBS and Longman Publication
Advanced Practical Inorganic Chemistry, Gurdeep Raj, Goel Publishing House,Meerut.
Advanced Practical Organic Chemistry, O.P. Agarwal, Krishna Prakashan Meerut
Advanced Physical Chemistry Experiment, Gurtu and Gurtu, Pragati prakashan, Meerut.
A Textbook of quantitative chemical analysis, VIth Edition Vogel, Pearson Education Limited.