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The Body’s Physical Systems
Chapter 2
1
The Neuron
2
Neural Communication
3
Neural Communication
Neurotransmitter
molecule
Receptor site on
receiving neuron
Receiving cell
membrane
Agonist mimics
Neurotransmitter
effects
Antagonist
blocks
Neurotransmitter
effects
4
5
CNS: Forebrain
Corpus callosum

Telencephalon



Limbic System
Cerebrum
Diencephalon

Thalamus &
Hypothalamus
6
The Limbic System
7
Brain stem
8
The Cerebral Cortex
9
The Nervous System
Nervous
system
Central
(brain and
spinal cord)
Peripheral
Autonomic (controls
self-regulated action of
internal organs and glands)
Skeletal (controls
voluntary movements of
skeletal muscles)
Sympathetic
(arousing)
Parasympathetic
(calming)
10
Sympathetic Nervous system
11
Parasympathetic Nervous System
12
The Endocrine System
13
The Digestive
System
14
The Digestive System Disorders

Peptic Ulcers


sores usually in the duodenum
Hepatitis

Viral inflammation of the liver
Cirrhosis
 Cancer

15
Metabolism
Basal Metabolic Rate
 Exercise Metabolic Rate
 Dietary Thermogenesis

16
The Cardiovascular System

Heart

Myocardium


Atria and Ventricles
Blood and Blood Flow
http://www.innerbody.com/image/card02.html
17
18
19
Blood Pressure

Systole & Diastole


Systolic: max force from  contraction
Diastolic: pressure between 
contractions

Fluid Dynamics





Cardiac output
Blood volume
Peripheral resistance
Elasticity of vessels
Viscosity of blood
20
Blood Pressure

Other factors that affect BP




Emotions: SNS
Environmental Temperature
Activity levels
Hypertension


<140 mmHg systolic, <90 mmHg diastolic
Risk factors





family Hx
body weight
age
gender
race
21
Diseases of the
Cardiovascular System
Atherosclerosis
 Ateriosclerosis
 Myocardial Infarction
 Angina Pectoris
 Stroke
 Aneurism

22
Immune System

Organs of the immune system

lymphocytes: white blood cells

from lymphatic or lymphoid organs:






bone marrow
thymus
lymph nodes
spleen
originate in bone marrow, migrate to thymus,
mature into leukocytes
lymph nodes capture antigens and hold
lymphocytes
 lymph vessels ultimately empty into blood supply
 can spread cancer cells

spleen filters blood
23
Soldiers of the Immune System


White blood cells

phagocytes: nonspecific immunity
 macrophages and monocytes

lymphocytes: respond to specific antigens
T-cells: cell-mediated immunity




Killer T cells
Helper T cells
Memory T cells
Suppressor T cells
24
Soldiers of the Immune System

B-cells: antibody-mediated immunity


B-cells become plasma cells which produce
antibodies (immunoglobulins - Ig)
 Ig’s attach to antigen and identify it for
destruction
Memory B-cells
25
The Immune Response
 Primary
vs. Secondary Response
 First lines of defense


skin
mucous membranes of respiratory and
digestive tracts
 Next: non-specific and specific
immune processes

phagocytes, B-cells, helper T-cells
destroy antigen
 Finally: killer T-cells destroy
invaded cells
26
Auto-immune Diseases
Rheumatoid arthritis: joints
 Rheumatic fever: heart muscle
 Multiple Sclerosis: myelin
 Lupus erythematosus: skin and kidneys
 Narcolepsy: “sleep attacks”

27